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Iminosugar-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Potential Anti-Pancreatic Cancer Agents

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2 Published in 2023 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics15051472

Abstract: The nicotinamide phosphoribosyltransferase (NAMPT) is considered a very promising therapeutic target because it is overexpressed in pancreatic cancer. Although many inhibitors have been prepared and tested, clinical trials have shown that NAMPT inhibition may result… read more here.

Keywords: pancreatic cancer; nicotinamide phosphoribosyltransferase; phosphoribosyltransferase nampt; iminosugar based ... See more keywords