Intravesical Immunomodulatory Imiquimod Enhances Bacillus Calmette‐Guérin Downregulation of Nonmuscle‐invasive Bladder Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2017.10.019
Abstract: &NA; The Toll‐like receptor (TLR)2/4 agonist bacillus Calmette‐Guérin (BCG) is the most efficient immunomodulatory treatment of nonmuscle‐invasive bladder cancer (NMIBC). BCG modulation by the TLR7 agonist imiquimod was evaluated in an immunocompetent animal model. We… read more here.
Keywords: bladder; histopathology; immunomodulatory; cancer ... See more keywords
Selective hemangioma cell dysfunction and apoptosis triggered by in vitro treatment with imiquimod.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2018.01.016
Abstract: Infantile hemangiomas are the most common benign tumors of infancy, characterized by unregulated angiogenesis and endothelial cells with high mitotic rate. Although spontaneous regression occurs, sometimes treatment is required and alternatives to corticosteroids should be… read more here.
Keywords: treatment; endothelial cells; imiquimod; hemangioma ... See more keywords
Transcriptomic analysis identifies differences in gene expression in actinic keratoses after treatment with imiquimod and between responders and non responders
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-88424-z
Abstract: The presence of actinic keratoses (AKs) increases a patient’s risk of developing squamous cell carcinoma by greater than six-fold. We evaluated the effect of topical treatment with imiquimod on the tumor microenvironment by measuring transcriptomic… read more here.
Keywords: treatment imiquimod; treatment; gene expression; imiquimod ... See more keywords
A case of topical imiquimod induced fatigue
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2022.2125266
Abstract: Abstract Topical imiquimod is used for a variety of common dermatologic lesions, including melanoma in-situ. As an immunomodulator, it is relatively well tolerated with minimal side effects, including scaling, erythema, and edema. Here we present… read more here.
Keywords: imiquimod induced; induced fatigue; imiquimod; topical imiquimod ... See more keywords
Chromoblastomycosis Treated With Posaconazole and Adjunctive Imiquimod: Lending Innate Immunity a Helping Hand
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DOI: 10.1093/ofid/ofad124
Abstract: Abstract Chromoblastomycosis (CBM) is a difficult-to-treat, chronic fungal infection of the skin and subcutaneous tissue. The evidence base for treatment is scarce, with no standardized therapeutic approach. Chronicity of CBM infection is postulated to be… read more here.
Keywords: chromoblastomycosis; hand; immunity; posaconazole adjunctive ... See more keywords
News and Notices
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DOI: 10.1097/01.hp.0000473560.81700.64
Abstract: word count. The seven comparisons we selected for the review were Mohs micrographic surgery vs. surgical excision, imiquimod vs. surgical excision, radiotherapy vs. surgical excision, methyl aminolaevulinate photodynamic therapy (MAL-PDT) vs. surgical excision, aminolaevulinic acid… read more here.
Keywords: cochrane review; news notices; surgical excision; imiquimod ... See more keywords
Topical Imiquimod Treatment of High-grade Cervical Intraepithelial Neoplasia (TOPIC-3): A Nonrandomized Multicenter Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunotherapy (Hagerstown, Md. : 1997)"
DOI: 10.1097/cji.0000000000000414
Abstract: Topical imiquimod could be an alternative, noninvasive, treatment modality for high-grade cervical intraepithelial neoplasia (CIN). However, evidence is limited, and there are no studies that compared treatment effectiveness and side effects of topical imiquimod cream… read more here.
Keywords: imiquimod treatment; high grade; imiquimod; treatment ... See more keywords
An extremely rare association of multiple familial trichoepitheliomas and hereditary multiple osteochondromas
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Dermatology"
DOI: 10.1111/ijd.14251
Abstract: References 1 Brenner S, Wolf R, Ruocco V. Contact pemphigus: a subgroup of induced pemphigus. Int J Dermatol 1994; 33: 843–845. 2 Sebaratnam DF, Martin LK, Rubin AI, et al. Reversible relapse of pemphigus foliaceus… read more here.
Keywords: topical imiquimod; dermatology; contact pemphigus; pemphigus foliaceus ... See more keywords
Extramammary Paget’s disease of the scrotum with complete response to imiquimod and photodynamic therapy
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DOI: 10.1136/bcr-2017-221696
Abstract: Extramammary Paget’s disease (EMPD) is a rare intraepithelial neoplasm with an extremely variable clinical course. The objective of this study was to determine if combination imiquimod and photodynamic therapy could induce remission of EMPD. A… read more here.
Keywords: photodynamic therapy; extramammary paget; therapy; imiquimod ... See more keywords
Topical Imiquimod as a Treatment Option for Nodular Basal Cell Carcinoma: A Systematic Review
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cutaneous Medicine and Surgery"
DOI: 10.1177/1203475420931770
Abstract: Background Surgical excision is considered standard treatment for nodular basal cell carcinoma (nBCC). However, patients who reject or are unsuited for surgery may benefit from imiquimod (IMQ) 5% cream as an alternative treatment. Objectives The… read more here.
Keywords: cell carcinoma; treatment; basal cell; imiquimod ... See more keywords
Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24634
Abstract: As a topical cancer immunotherapy, the toll-like receptor 7 ligand imiquimod activates tumor regression via stimulation of immune cell infiltration and cytotoxic responses. Imiquimod also exerts direct pro-apoptotic effects on tumor cells in vitro, but… read more here.
Keywords: cell; tasmanian devil; expression; imiquimod ... See more keywords