The in vitro effects of trimethyltin on the androgen biosynthesis of rat immature Leydig cells.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology"
DOI: 10.1016/j.tox.2020.152577
Abstract: Trimethyltin (TMT) is widely used in industry and agriculture. The present study aims to clarify the effects of in vitro TMT exposure on androgen biosynthesis and metabolism in immature Leydig cells (ILCs), and to unveil… read more here.
Keywords: androgen biosynthesis; leydig cells; immature leydig;
Flurbiprofen inhibits androgen productions in rat immature Leydig cells.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.8b00404
Abstract: Flurbiprofen is one of the nonsteroidal anti-inflammatory drugs. Whether flurbiprofen affects androgen biosynthesis in Leydig cells is still unknown. Immature Leydig cells (ILCs) isolated from 35-day-old male Sprague Dawley rats were cultured with 0-100 µM… read more here.
Keywords: inhibits androgen; flurbiprofen inhibits; leydig; 100 flurbiprofen ... See more keywords
Butorphanol inhibits androgen biosynthesis and metabolism in rat immature Leydig cells in vitro.
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DOI: 10.1139/cjpp-2023-0191
Abstract: Butorphanol is a synthetic opioid analgesic medication that is primarily used for the management of pain. Butorphanol may have an inhibitory effect on androgen biosynthesis and metabolism in rat immature Leydig cells. The objective of… read more here.
Keywords: immature leydig; biosynthesis metabolism; androgen biosynthesis; butorphanol ... See more keywords