ORF45, a multifunctional immediate early and tegument protein of KSHV
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28659
Abstract: Kaposi sarcoma‐associated herpesvirus (KSHV) is the etiological agent of several human diseases, including Kaposi sarcoma, primary effusion lymphoma, and a subset of multicentric Castleman's disease. KSHV uses its gene products to manipulate many aspects of… read more here.
Keywords: tegument protein; multifunctional immediate; immediate early; kshv ... See more keywords
Perturbed expression pattern of the immediate early gene Arc in the dentate gyrus of GluA1 C‐terminal palmitoylation‐deficient mice
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12044
Abstract: AMPA receptors predominantly mediate fast excitatory synaptic transmission in the mammalian brain. Post‐translational protein S‐palmitoylation of AMPA receptor GluA subunits at their C‐termini reversibly controls the receptors trafficking to and from excitatory glutamatergic synapses. Excitatory… read more here.
Keywords: palmitoylation; dentate gyrus; immediate early; expression ... See more keywords
Increased herpes zoster risk associated with poor HLA-A immediate early 62 protein (IE62) affinity
Sign Up to like & getrecommendations! Published in 2017 at "Immunogenetics"
DOI: 10.1007/s00251-017-1047-x
Abstract: Around 30% of individuals will develop herpes zoster (HZ), caused by the varicella zoster virus (VZV), during their life. While several risk factors for HZ, such as immunosuppressive therapy, are well known, the genetic and… read more here.
Keywords: protein; risk; immediate early; herpes zoster ... See more keywords
Partial complementation between the immediate early proteins ICP4 of herpes simplex virus type 1 and IE180 of pseudorabies virus.
Sign Up to like & getrecommendations! Published in 2020 at "Virus research"
DOI: 10.1016/j.virusres.2020.197896
Abstract: We previously described that the immediate early (IE) IE180 protein of PRV can down-regulate the transactivation of the ICP4 promoter of HSV-1, and that the d120 virus (an ICP4-deficient HSV-1 strain) can partially replicate its… read more here.
Keywords: complementation immediate; immediate early; partial complementation; ie180 ... See more keywords
Neural activity mapping of bumble bee (Bombus ignitus) brains during foraging flight using immediate early genes
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-64701-1
Abstract: Honey bees and bumble bees belong to the same family (Apidae) and their workers exhibit a division of labor, but the style of division of labor differs between species. The molecular and neural bases of… read more here.
Keywords: bombus ignitus; immediate early; foraging flight; flight ... See more keywords
MED12-related XLID disorders are dose-dependent of immediate early genes (IEGs) expression
Sign Up to like & getrecommendations! Published in 2017 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddx099
Abstract: Mediator occupies a key role in protein coding genes expression in mediating the contacts between gene specific factors and the basal transcription machinery but little is known regarding the role of each Mediator subunits. Mutations… read more here.
Keywords: immediate early; expression; med12; genes iegs ... See more keywords
Immediate Early and Delayed Implants: A 2-Year Prospective Cohort Study of 131 Transmucosal Flapless Implants Placed in Sites With Different Pre-extractive Endodontic Infections
Sign Up to like & getrecommendations! Published in 2017 at "Implant Dentistry"
DOI: 10.1097/id.0000000000000666
Abstract: Introduction: To evaluate clinical outcome of early, immediate, and delayed transmucosal implants placed in patients affected by acute/chronic endodontic lesions. Materials and Methods: Eighty-five consecutive patients received 131 titanium implants with zirconium-oxide blasted surface. Pre-extractive… read more here.
Keywords: implants placed; transmucosal; immediate early; group ... See more keywords
Chromatin-Remodeling Factor SPOC1 Acts as a Cellular Restriction Factor against Human Cytomegalovirus by Repressing the Major Immediate Early Promoter
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.00342-18
Abstract: ABSTRACT The cellular protein SPOC1 (survival time-associated PHD [plant homeodomain] finger protein in ovarian cancer 1) acts as a regulator of chromatin structure and the DNA damage response. It binds H3K4me2/3-containing chromatin and promotes DNA… read more here.
Keywords: restriction factor; immediate early; hcmv; cytomegalovirus ... See more keywords
Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in OriLyt
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03144-22
Abstract: HCMV is an important human pathogen associated with complications in transplant patients and birth defects. The complex program of viral gene expression is regulated by both viral proteins and host factors. ABSTRACT Human cytomegalovirus (HCMV)… read more here.
Keywords: role; early proteins; immediate early; expression ... See more keywords
Antiviral activity of mitoxantrone dihydrochloride against human herpes simplex virus mediated by suppression of the viral immediate early genes
Sign Up to like & getrecommendations! Published in 2019 at "BMC Microbiology"
DOI: 10.1186/s12866-019-1639-8
Abstract: BackgroundHSV-1 is a common pathogen that infects 50–90% of the human population worldwide. HSV-1 causes numerous infection-related diseases, some of which are severely life-threatening. There are antiviral medications with activity against HSV-1. However, with the… read more here.
Keywords: hsv; immediate early; mitoxantrone dihydrochloride; early genes ... See more keywords
Retrosplenial cortex in spatial memory: focus on immediate early genes mapping
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Brain"
DOI: 10.1186/s13041-021-00880-w
Abstract: The ability to form, retrieve and update autobiographical memories is one of the most fascinating features of human behavior. Spatial memory, the ability to remember the layout of the external environment and to navigate within… read more here.
Keywords: retrosplenial cortex; early genes; cortex spatial; spatial memory ... See more keywords