Clinical evaluation of switching from immediate‐release to prolonged‐release lithium in bipolar patients, poorly tolerant to lithium immediate‐release treatment: A randomized clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2485
Abstract: The effect of switching from lithium immediate release (Li‐IR) to lithium prolonged release (Li‐PR) on lithium‐induced tremor after 1 and 12 weeks of treatment was evaluated in a randomized, multicenter, open trial, in bipolar patients… read more here.
Keywords: immediate release; release; lithium; lithium immediate ... See more keywords
Pharmacokinetics and Pharmacodynamics of Lansoprazole/Sodium Bicarbonate Immediate-release Capsules in Healthy Chinese Subjects: An Open, Randomized, Controlled, Crossover, Single-, and Multiple-dose Trial.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.1251
Abstract: Proton pump inhibitors (PPIs) differ in onset of action and bioavailability. This trial was conducted to investigate the pharmacokinetics and pharmacodynamics of an immediate-release capsule formulation containing lansoprazole 30 mg and sodium bicarbonate 1100 mg (T preparation)… read more here.
Keywords: lansoprazole sodium; single multiple; pharmacokinetics pharmacodynamics; preparation ... See more keywords
Extended release versus immediate release tacrolimus in kidney transplant recipients: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-018-2512-7
Abstract: PurposeTo compare the estimated glomerular filtration rate (eGFR) at 12 months together with other outcomes among adult kidney transplant recipients (KTRs) who received extended release, once daily tacrolimus (ER-Tac) compared to those who received the immediate… read more here.
Keywords: extended release; immediate release; kidney transplant; transplant recipients ... See more keywords
Phase II/III, randomized, double-blind, parallel-group study of monthly delayed-release versus daily immediate-release risedronate tablets in Japanese patients with involutional osteoporosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Metabolism"
DOI: 10.1007/s00774-019-01031-x
Abstract: Absorption of oral immediate-release (IR) risedronate tablets is reduced by food intake, thus a delayed-release (DR) tablet has been developed to overcome the necessity of taking IR tablets under fasting conditions. This randomized, double-blind, phase… read more here.
Keywords: phase; immediate release; breakfast; following breakfast ... See more keywords
Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Proguanil Hydrochloride.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2018.03.009
Abstract: Literature data relevant to the decision to waive in vivo bioequivalence testing for the approval of generic immediate release solid oral dosage forms of proguanil hydrochloride are reviewed. To elucidate the Biopharmaceutics Classification System (BCS) classification,… read more here.
Keywords: hydrochloride; immediate release; solid oral; release solid ... See more keywords
Preparation and evaluation of 1-deoxynojirimycin sustained-release pellets vs conventional immediate-release tablets
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2017.1321694
Abstract: Abstract 1-Deoxynojirimycin sustained-release pellets, which exhibit known release and absorption profiles, are used for the treatment of diabetes mellitus. In this study, a fluidised bed coater was employed to prepare new, drug-loaded pellets. In the… read more here.
Keywords: immediate release; release pellets; deoxynojirimycin sustained; sustained release ... See more keywords
Cost-effectiveness of tapentadol immediate release versus oxycodone immediate release for acute post-operative pain after major hip surgeries.
Sign Up to like & getrecommendations! Published in 2021 at "Current medical research and opinion"
DOI: 10.1080/03007995.2021.1993161
Abstract: OBJECTIVE To evaluate the cost-effectiveness of tapentadol immediate release (IR) versus oxycodone IR for post-operative pain after major hip surgery. METHODS This study has been conducted using an Australian societal perspective, focusing on adult patients… read more here.
Keywords: immediate release; major hip; cost effectiveness; oxycodone ... See more keywords
Directly compressible formulation of immediate release rosuvastatin calcium tablets stabilized with tribasic calcium phosphate
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2073370
Abstract: Abstract Reliable and stable tablet formulations for rosuvastatin calcium (RSC) in four strengths: 5 mg, 10 mg, 20 mg, and 40 mg have been developed. Rosuvastatin is a cholesterol-lowering statin drug and is known to be unstable during storage.… read more here.
Keywords: calcium; calcium phosphate; directly compressible; tribasic calcium ... See more keywords
A Randomized, Double-Blind, Crossover Study to Investigate the Pharmacokinetics of Extended-Release Melatonin Compared to Immediate-Release Melatonin in Healthy Adults.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of dietary supplements"
DOI: 10.1080/19390211.2023.2206475
Abstract: Exogenous melatonin can be helpful for treatment of some sleep disorders. However, immediate-release formulations are rapidly absorbed and cleared from the body making it difficult to provide coverage for an entire sleep period. Extended-release melatonin… read more here.
Keywords: compared immediate; release; immediate release; extended release ... See more keywords
Diabetes is a significant and independent predictor for tacrolimus immediate release and LCP‐tacrolimus conversion ratios
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Transplantation"
DOI: 10.1111/ctr.14944
Abstract: Diabetes (DM) is a common comorbidity in transplant patients with known effects on gastrointestinal (GI) motility and absorption; however, DM's impact on immediate release (IR) tacrolimus to LCP‐tacrolimus (LCP) conversion ratios has not been studied.… read more here.
Keywords: conversion ratios; conversion; lcp conversion; immediate release ... See more keywords
Overdosing on immediate-release morphine solution has predictable adverse effects
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/13993003.01091-2017
Abstract: Prescribing responsibility inherently includes adequate ongoing monitoring for medication. The adverse effects of an overdose of immediate-release morphine in a recent letter to the ERJ are well known http://ow.ly/71D130dMLYd read more here.
Keywords: morphine solution; immediate release; release morphine; overdosing immediate ... See more keywords