Cobalt chloride-simulated hypoxia elongates primary cilia in immortalized human retina pigment epithelial-1 cells.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.03.097
Abstract: Primary cilia are microtubule-based organelles that are involved in sensing micro-environmental cues and regulating cellular homeostasis via triggering signaling cascades. Hypoxia is one of the most common environmental stresses that organ and tissue cells may… read more here.
Keywords: cobalt chloride; human retina; immortalized human; simulated hypoxia ... See more keywords
Sulfur mustard analog 2-chloroethyl ethyl sulfide increases triglycerides by activating DGAT1-dependent biogenesis and inhibiting PGC1ɑ-dependent fat catabolism in immortalized human bronchial epithelial cells
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2022.2124898
Abstract: Abstract Using sulfur mustard analog 2-chloroethyl ethyl sulfide (CEES), we established an in vitro model by poisoning cultured immortalized human bronchial epithelial cells. Nile Red staining revealed lipids accumulated 24 h after a toxic dose of… read more here.
Keywords: ethyl sulfide; mustard analog; immortalized human; sulfur mustard ... See more keywords
Identification of an Immortalized Human Airway Epithelial Cell Line with Dyskinetic Cilia
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2017-0188oc
Abstract: Abstract Primary ciliary dyskinesia is an inherited, currently incurable condition. In the respiratory system, primary ciliary dyskinesia causes impaired functioning of the mucociliary escalator, leading to nasal congestion, cough, and recurrent otitis media, and commonly… read more here.
Keywords: epithelial cell; cell line; immortalized human; cilia ... See more keywords
The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells
Sign Up to like & getrecommendations! Published in 2017 at "Drug Metabolism Letters"
DOI: 10.2174/1872312811666170127160931
Abstract: Objective: Drug therapy is occasionally accompanied by an idiosyncratic severe toxicity, which occurs very rarely, but can lead to patient mortality. Methazolamide, an anti-glaucomatous agent, could cause severe skin eruptions called Stevens-Johnson syndrome/toxic epidermal necrolyis… read more here.
Keywords: metabolism; immortalized human; hacat cells; human keratinocytes ... See more keywords
Pro-Inflammatory Activation of a New Immortalized Human Microglia Cell Line
Sign Up to like & getrecommendations! Published in 2019 at "Brain Sciences"
DOI: 10.3390/brainsci9050111
Abstract: The characterization of human microglia has been hampered by poor availability of human cell sources. However, microglia is involved in the physiopathology of multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, HIV dementia, retinal degenerative diseases, cancer,… read more here.
Keywords: human microglia; cell line; cell; immortalized human ... See more keywords