Resolving the Mutually Exclusive Immune Responses of Chitosan with Nanomechanics and Immunological Assays
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102667
Abstract: Multifaceted functions displayed by both pro‐ and anti‐inflammatory properties of chitosan hinder its effective development as an immunomodulatory agent. Herein, the contributions of the bending stiffness of chitosan with regard to its immune regulatory properties… read more here.
Keywords: anti inflammatory; mutually exclusive; resolving mutually; immunological assays ... See more keywords
Ferroptosis Signature Shapes the Immune Profiles to Enhance the Response to Immune Checkpoint Inhibitors in Head and Neck Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202204514
Abstract: As a type of immunogenic cell death, ferroptosis participates in the creation of immunoactive tumor microenvironments. However, knowledge of spatial location of tumor cells with ferroptosis signature in tumor environments and the role of ferroptotic… read more here.
Keywords: head neck; ferroptosis signature; hnscc; immune ... See more keywords
Immune signaling pathways in the endoparasitoid, Pteromalus puparum.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21629
Abstract: Parasitoids serve as effective biocontrol agents for agricultural pests. However, they face constant challenges from host immune defense and numerous pathogens and must develop potent immune defense against these threats. Despite the recent advances in… read more here.
Keywords: immune; immune related; pteromalus puparum; endoparasitoid pteromalus ... See more keywords
Progression-free survival assessed per immune-related or conventional response criteria, which is the better surrogate endpoint for overall survival in trials of immune-checkpoint inhibitors in lung cancer: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer medicine"
DOI: 10.1002/cam4.4347
Abstract: Progression-free survival (PFS) has been used as a surrogate endpoint for overall survival (OS) in lung cancer trials. The pattern of response to immune-checkpoint inhibitors (ICIs) differs from that to conventional chemotherapy, so immune-related response… read more here.
Keywords: immune; response; lung cancer; cancer ... See more keywords
Development and validation of an immune‐related prognosis signature associated with hypoxia and ferroptosis in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4556
Abstract: Hypoxia and ferroptosis are crucial in the occurrence and development of hepatocellular carcinoma (HCC), and they both affect the immune status of the tumor microenvironment. Previous studies have also shown a link between hypoxia and… read more here.
Keywords: hepatocellular carcinoma; development; hypoxia ferroptosis; immune ... See more keywords
Identification of a combined apoptosis and hypoxia gene signature for predicting prognosis and immune infiltration in breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer medicine"
DOI: 10.1002/cam4.4755
Abstract: BACKGROUND Breast cancer (BC) is the most common malignant tumor worldwide. Apoptosis and hypoxia are involved in the progression of BC, but reliable biomarkers for these have not been developed. We hope to explore a… read more here.
Keywords: prognosis; cancer; signature; gene ... See more keywords
Five EMT‐related genes signature predicts overall survival and immune environment in microsatellite instability‐high gastric cancer
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DOI: 10.1002/cam4.4975
Abstract: Microsatellite instability‐high (MSI‐H) subgroup of gastric cancer (GC) is characterized by a high tumor mutational burden, increased lymphocytic infiltration, and enhanced inflammatory cytokines. GC patients with MSI‐H status have a good response to immune checkpoint… read more here.
Keywords: microsatellite instability; instability high; gastric cancer; immune ... See more keywords
Self‐Assembled Nano‐Immunostimulant for Synergistic Immune Activation
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DOI: 10.1002/cbic.201700246
Abstract: Immunotherapy has become one of the most promising therapies for the treatment of diseases. Synthetic immunostimulants and nanomaterial immunostimulant systems are indispensable for the activation of the immune system in cancer immunotherapy. Herein, a strategy… read more here.
Keywords: immune; immune activation; synergistic immune; self assembled ... See more keywords
In‐silico generation of high‐dimensional immune response data in patients using a deep neural network
Sign Up to like & getrecommendations! Published in 2022 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24709
Abstract: Technologies for single‐cell profiling of the immune system have enabled researchers to extract rich interconnected networks of cellular abundance, phenotypical and functional cellular parameters. These studies can power machine learning approaches to understand the role… read more here.
Keywords: immune response; high dimensional; immune; silico generation ... See more keywords
Immune and environment‐driven gene expression during invasion: An eco‐immunological application of RNA‐Seq
Sign Up to like & getrecommendations! Published in 2019 at "Ecology and Evolution"
DOI: 10.1002/ece3.5249
Abstract: Abstract Host–pathogen associations change rapidly during a biological invasion and are predicted to impose strong selection on immune function. It has been proposed that the invader may experience an abrupt reduction in pathogen‐mediated selection (“enemy… read more here.
Keywords: immune; invasion; selection; expression ... See more keywords
Tryptophan and the innate intestinal immunity: Crosstalk between metabolites, host innate immune cells and microbiota.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of immunology"
DOI: 10.1002/eji.202149401
Abstract: The intestinal mucosal barrier is critical for the absorption of nutrients and the health of both humans and animals. Recent publications from clinical and experimental studies have shown the importanceof the nutrients-bacteria-host interaction for the… read more here.
Keywords: immune; tryptophan innate; host; intestinal homeostasis ... See more keywords