Selenium metabolism and regulation of immune cells in immune‐associated diseases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30824
Abstract: Selenium, as one of the essential microelements, plays an irreplaceable role in metabolism regulation and cell survival. Selenium metabolism and regulation have great effects on physiological systems especially the immune system. Therefore, selenium is tightly… read more here.
Keywords: metabolism; immune associated; metabolism regulation; selenium metabolism ... See more keywords
Integrative multiomics analysis highlights immune-cell regulatory mechanisms and shared genetic architecture for 14 immune-associated diseases and cancer outcomes.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2021.10.003
Abstract: Developing functional insight into the causal molecular drivers of immunological disease is a critical challenge in genomic medicine. Here, we systematically apply Mendelian randomization (MR), genetic colocalization, immune-cell-type enrichment, and phenome-wide association methods to investigate… read more here.
Keywords: immune cell; immune associated; cancer; cell ... See more keywords
Immune and associated molecular markers - their role in fibrotic dermal scarring.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental dermatology"
DOI: 10.1111/exd.14734
Abstract: INTRODUCTION Raised dermal scars including hypertrophic, keloid and scalp-associated fibrosing Folliculitis Keloidalis Nuchae (FKN) are fibrotic disorders that mostly occur following cutaneous injury. They are characterized by increased extracellular matrix (ECM) deposition, primarily excessive collagen… read more here.
Keywords: immune associated; dermal scarring; molecular markers; associated molecular ... See more keywords
Bioinformatics analysis identifies immune-related gene signatures and subtypes in diabetic nephropathy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1048139
Abstract: Background Systemic inflammation and immune response are involved in the pathogenesis of diabetic nephropathy (DN). However, the specific immune-associated signature during DN development is unclear. Our study aimed to reveal the roles of immune-related genes… read more here.
Keywords: immune associated; immune related; analysis; immune ... See more keywords
A Novel Framework to Predict Breast Cancer Prognosis Using Immune-Associated LncRNAs
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DOI: 10.3389/fgene.2020.634195
Abstract: Background: Breast cancer (BC) is one of the most frequently diagnosed malignancies among females. As a huge heterogeneity of malignant tumor, it is important to seek reliable molecular biomarkers to carry out the stratification for… read more here.
Keywords: analysis; associated lncrnas; breast cancer; immune associated ... See more keywords
Immune-associated pivotal biomarkers identification and competing endogenous RNA network construction in post-operative atrial fibrillation by comprehensive bioinformatics and machine learning strategies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.974935
Abstract: Background Atrial fibrillation (AF) is the most common arrhythmia. Previous studies mainly focused on identifying potential diagnostic biomarkers and treatment strategies for AF, while few studies concentrated on post-operative AF (POAF), particularly using bioinformatics analysis… read more here.
Keywords: network; immune associated; machine learning; competing endogenous ... See more keywords
Development and Verification of the Amino Metabolism-Related and Immune-Associated Prognosis Signature in Gliomas
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.774332
Abstract: Aberrant reprogramming of metabolism has been considered a hallmark in various malignant tumors. The metabolic changes of amino acid not only have dramatic effects in cancer cells but also influence their immune-microenvironment in gliomas. However,… read more here.
Keywords: risk; metabolism; metabolism related; immune associated ... See more keywords