The spinal cord-gut-immune axis as a master regulator of health and neurological function after spinal cord injury
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2019.113085
Abstract: Most spinal cord injury (SCI) research programs focus only on the injured spinal cord with the goal of restoring locomotor function by overcoming mechanisms of cell death or axon regeneration failure. Given the importance of… read more here.
Keywords: cord; immune axis; cord gut; gut immune ... See more keywords
Citrullinated human fibrinogen triggers arthritis through an inflammatory response mediated by IL-23/IL-17 immune axis.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108363
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease that causes joint destruction. Although its etiology remains unknown, citrullinated proteins have been considered as an auto-antigen able to trigger an inflammatory response in RA. Herein, we modified… read more here.
Keywords: mediated immune; citrullinated human; response; inflammatory response ... See more keywords
The spinal cord-gut-immune axis and its implications on therapeutic development for spinal cord injury.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurotrauma"
DOI: 10.1089/neu.2022.0264
Abstract: Spinal cord injury (SCI) affects approximately 1.3 million people living in the United States. Most research efforts have been focused on reversing paralysis, as this is arguably the most defining feature of SCI. The damage… read more here.
Keywords: cord; immune axis; cord gut; gut immune ... See more keywords
Gut Microbiota-Immune Axis in the Regulation of Rheumatoid Arthritis: From Mechanism to Precision Probiotic Strategies.
Sign Up to like & getrecommendations! Published in 2025 at "Modern rheumatology"
DOI: 10.1093/mr/roaf081
Abstract: Rheumatoid Arthritis (RA) is a progressive autoimmune disorder with substantial global health and economic impacts. Despite advancements in conventional therapies, biologics, and targeted drugs, challenges such as adverse effects, cost, and interindividual heterogeneity underscore the… read more here.
Keywords: precision; gut microbiota; microbiota immune; immune ... See more keywords
Role of altered IL‐33/ST2 immune axis in the immunobiology of Guillain‐Barré syndrome
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15334
Abstract: The IL‐33/ST2 immune axis plays crucial roles in infection and immunity. A dysregulated IL‐33/ST2 axis can induce autoimmune reaction and inflammatory responses. Guillain‐Barré syndrome (GBS) is an acute peripheral neuropathy, mostly caused by post‐infection autoimmunity.… read more here.
Keywords: immune axis; role; st2 immune; barr syndrome ... See more keywords
Impacts of foodborne inorganic nanoparticles on the gut microbiota-immune axis: potential consequences for host health
Sign Up to like & getrecommendations! Published in 2020 at "Particle and Fibre Toxicology"
DOI: 10.1186/s12989-020-00349-z
Abstract: Background In food toxicology, there is growing interest in studying the impacts of foodborne nanoparticles (NPs, originating from food additives, food supplements or food packaging) on the intestinal microbiome due to the important and complex… read more here.
Keywords: immune axis; gut microbiota; microbiota immune; health ... See more keywords
Metabolic-Inflammatory Syndrome: Decoding the Metabolic-Immune Axis for Precision Intervention.
Sign Up to like & getrecommendations! Published in 2025 at "Aging and disease"
DOI: 10.14336/ad.2025.1125
Abstract: Metabolic-inflammatory syndrome represents a major global health challenge, closely linked to diabetes, cardiovascular disease, obesity, and non-alcoholic fatty liver disease. The core of these disorders involves remodeling of metabolic pathways under nutritional stress and the… read more here.
Keywords: metabolic immune; metabolic inflammatory; inflammatory syndrome; immune axis ... See more keywords
Beyond viral suppression: decoding the mitochondrial-immune axis in HIV-associated inflammation and immune dysfunction
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2025.1686785
Abstract: Antiretroviral therapy (ART) has transformed HIV into a chronic, manageable condition, yet people living with HIV (PLWH) continue to experience persistent immune activation and systemic inflammation that drive long-term comorbidities, including neurocognitive impairment and cardiovascular… read more here.
Keywords: hiv; beyond viral; inflammation; axis hiv ... See more keywords
Neuro-immune axis in atherosclerosis: mechanisms of regulation and therapeutic opportunities
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1619338
Abstract: Atherosclerosis, the leading cause of cardiovascular morbidity and mortality worldwide, is now firmly established as a chronic immune-mediated disorder rather than a purely lipid-storage disease. Accumulating evidence has uncovered a previously underappreciated dimension of atherogenesis:… read more here.
Keywords: atherosclerosis; axis atherosclerosis; regulation; atherosclerosis mechanisms ... See more keywords
The innate immune axis drives aortic dissection pathogenesis through inflammation and presents novel therapeutic targets
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1654622
Abstract: Acute aortic dissection (AAD) is a life-threatening cardiovascular emergency characterized by aortic layer separation and false lumen formation, with high mortality rates. Emerging evidence highlights the critical role of innate immunity in AD pathogenesis. Innate… read more here.
Keywords: aortic dissection; innate immune; inflammation; pathogenesis ... See more keywords
Infections in the Developing Brain: The Role of the Neuro-Immune Axis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.805786
Abstract: Central nervous system (CNS) infections occur more commonly in young children than in adults and pose unique challenges in the developing brain. This review builds on the distinct vulnerabilities in children's peripheral immune system (outlined… read more here.
Keywords: developing brain; neuro immune; immune axis; role ... See more keywords