Immune-Based Therapy for COVID-19.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-63761-3_26
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel zoonotic virus identified as the cause of coronavirus disease 2019 (COVID-19) that has crossed species and infected humans. In order to develop new insights on… read more here.
Keywords: covid; sars cov; immune based; immune response ... See more keywords
Establishment and validation of an immune-based prognostic score model in glioblastoma.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106636
Abstract: BACKGROUND Immune escape is one of the landmark features of glioblastoma (GBM). Immunotherapy is undoubtedly a revolution in the field of tumor treatment, especially the application of immune checkpoint inhibitors and CAR-T cells, which have… read more here.
Keywords: gbm; model; immune based; score model ... See more keywords
Two immune-based methods using immortalized porcine kidney macrophages for quantifying neutralizing activity against porcine reproductive and respiratory syndrome virus-2.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2022.114494
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) causes a serious infectious disease in pigs in farms worldwide. Neutralizing antibody titer is an effective index for evaluating immunity to PRRSV; however, PRRSV has different neutralizing cross-reactivity… read more here.
Keywords: immune based; based methods; neutralizing activity; activity porcine ... See more keywords
CTLA-4 (CD152): A versatile receptor for immune-based therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in immunology"
DOI: 10.1016/j.smim.2019.101298
Abstract: Coreceptor-based immunotherapy is a rapidly developing approach to treat cancer patients. Among those targeted receptors, CTLA-4 is the primary attenuator of adaptive immune responses and the most prominent and extensively investigated molecule in this field.… read more here.
Keywords: immune; ctla cd152; versatile receptor; cd152 versatile ... See more keywords
Emerging immune-based technologies for high-grade gliomas
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2022.2110072
Abstract: ABSTRACT Introduction The selection of a tailored and successful strategy for high-grade gliomas (HGGs) treatment is still a concern. The abundance of aberrant mutations within the heterogenic genetic landscape of glioblastoma strongly influences cell expansion,… read more here.
Keywords: grade gliomas; emerging immune; immune based; high grade ... See more keywords
Integrative transcriptome analysis of malignant pleural mesothelioma reveals a clinically relevant immune-based classification
Sign Up to like & getrecommendations! Published in 2021 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2020-001601
Abstract: Background Malignant pleural mesothelioma (MPM) is a rare and aggressive neoplasia affecting the lung mesothelium. Immune checkpoint inhibitors (ICI) in MPM have not been extremely successful, likely due to poor identification of suitable candidate patients… read more here.
Keywords: classification; pleural mesothelioma; malignant pleural; clinically relevant ... See more keywords
Integrated Analysis Identifies an Immune-Based Prognostic Signature for the Mesenchymal Identity in Gastric Cancer
Sign Up to like & getrecommendations! Published in 2020 at "BioMed Research International"
DOI: 10.1155/2020/9780981
Abstract: Background Gastric cancer (GC) has been divided into four molecular subtypes, of which the mesenchymal subtype has the poorest survival. Our goal is to develop a prognostic signature by integrating the immune system and molecular… read more here.
Keywords: prognostic signature; gastric cancer; analysis; based prognostic ... See more keywords
Development and Verification of an Immune-Based Gene Signature for Risk Stratification and Immunotherapeutic Efficacy Assessment in Gastric Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Disease Markers"
DOI: 10.1155/2021/4251763
Abstract: Objective Due to the molecular heterogeneity of gastric cancer, only minor patients respond to immunotherapeutic schemes. This study is aimed at developing an immune-based gene signature for risk stratification and immunotherapeutic efficacy assessment in gastric… read more here.
Keywords: risk; gastric cancer; based gene; signature ... See more keywords
The Predictive Value of Three Variables in Patients with Metastatic Renal Cell Carcinoma Treated with Immune-Based Combination Therapies in Randomized Clinical Trials: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/7733251
Abstract: Background Sex, age, and International Metastatic Renal-Cell Carcinoma Database Consortium (IMDC) prognostic risk may influence the immune response. Nonetheless, the correlation between these factors and the survival benefits of immune-based combination therapies in patients with… read more here.
Keywords: combination therapies; renal cell; based combination; metastatic renal ... See more keywords
Recent Advances in Immune-based Therapies for Type 1 Diabetes.
Sign Up to like & getrecommendations! Published in 2022 at "Hormone research in paediatrics"
DOI: 10.1159/000524866
Abstract: BACKGROUND Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by progressive destruction of the pancreatic beta-cells leading to a lifelong dependence on insulin. It is associated with an increased morbidity and mortality from… read more here.
Keywords: disease; type diabetes; advances immune; beta cell ... See more keywords
Treatment duration with immune-based therapies in Cancer: an enigma
Sign Up to like & getrecommendations! Published in 2018 at "Journal for Immunotherapy of Cancer"
DOI: 10.1186/s40425-018-0465-0
Abstract: Unlike chemotherapy treatments that target the tumor itself (rather nonspecifically), immune-based therapies attempt to harness the power of an individual patient’s immune system to combat cancer. Similar to chemotherapeutic agents, the dosage and Administration section… read more here.
Keywords: immune; based therapies; treatment; duration ... See more keywords