Risk Factors for the Development of Bullous Pemphigoid in US Patients Receiving Immune Checkpoint Inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.0354
Abstract: Importance De novo bullous pemphigoid (BP) is a rare immune-mediated adverse event from immune checkpoint inhibitors (ICIs) that can necessitate permanent discontinuation of the anticancer therapy, but the risk factors for developing this toxic effect… read more here.
Keywords: bullous pemphigoid; immune checkpoint; ici; risk factors ... See more keywords
Psoriasis Risk With Immune Checkpoint Inhibitors.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2024.4129
Abstract: Importance Immune checkpoint inhibitors (ICIs) are recognized as revolutionary cancer therapies but have raised concerns about immune-related adverse events, including the development of autoimmune diseases. Objective To evaluate the psoriasis risk associated with the use… read more here.
Keywords: psoriasis risk; cancer; immune checkpoint; risk ... See more keywords
Comparison of Long-term Survival Benefits in Trials of Immune Checkpoint Inhibitor vs Non–Immune Checkpoint Inhibitor Anticancer Agents Using ASCO Value Framework and ESMO Magnitude of Clinical Benefit Scale
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DOI: 10.1001/jamanetworkopen.2019.6803
Abstract: Key Points Question How frequently do immune checkpoint inhibitor (ICI) agents vs non-ICI agents qualify for American Society of Clinical Oncology Value Framework version 2 (ASCO-VF v2) tail-of-the-curve bonuses or European Society of Medical Oncology… read more here.
Keywords: immune checkpoint; oncology; checkpoint inhibitor; long term ... See more keywords
Immune Checkpoint Inhibitors and Immune-Related Adverse Events in Patients With Advanced Melanoma
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DOI: 10.1001/jamanetworkopen.2020.1611
Abstract: This systematic review and meta-analysis evaluates the immune checkpoint inhibitor regimens used along with the incidence of adverse events reported in randomized clinical trials for treatment of advanced melanoma. read more here.
Keywords: immune checkpoint; advanced melanoma; checkpoint inhibitors; inhibitors immune ... See more keywords
Assessment of Trends in Second Primary Cancers in Patients With Metastatic Melanoma From 2005 to 2016
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DOI: 10.1001/jamanetworkopen.2020.28627
Abstract: Key Points Question When compared with prior therapies, are immune checkpoint inhibitors for metastatic melanoma associated with development of second primary cancers? Findings In this cohort study of 5016 patients with metastatic melanoma between 2005… read more here.
Keywords: immune checkpoint; second primary; primary cancers; checkpoint inhibitors ... See more keywords
Association of Anticancer Immune Checkpoint Inhibitors With Patient-Reported Outcomes Assessed in Randomized Clinical Trials
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.26252
Abstract: This systematic review and meta-analysis of randomized clinical trials involving patients with solid tumors assesses the association of immune checkpoint inhibitors with patient-reported quality of life. read more here.
Keywords: inhibitors patient; immune checkpoint; checkpoint inhibitors; clinical trials ... See more keywords
Analysis of Cancer Survival Associated With Immune Checkpoint Inhibitors After Statistical Adjustment
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DOI: 10.1001/jamanetworkopen.2022.27211
Abstract: Key Points Question Is there a difference in survival outcomes associated with immune checkpoint inhibitor therapy compared with chemotherapy when corrected for error introduced by Cox proportional hazards analysis? Findings In this systematic review and… read more here.
Keywords: immune checkpoint; survival; analysis; adjustment ... See more keywords
Accuracy of a Text Intervention to Minimize the Burden of Cancer Care Among Patients Treated With Immune Checkpoint Inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.28452
Abstract: This cross-sectional study examines whether patients with cancer without symptoms of immune checkpoint inhibitor toxic effects can be accurately identified using a text message–based triage instrument and safely proceed to treatment. read more here.
Keywords: immune checkpoint; intervention minimize; text intervention; cancer ... See more keywords
Comparative Effectiveness of Immune Checkpoint Inhibitors vs Chemotherapy in Patients With Metastatic Colorectal Cancer With Measures of Microsatellite Instability, Mismatch Repair, or Tumor Mutational Burden
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.52244
Abstract: This comparative effectiveness research study compares outcomes of first-line therapy with immune checkpoint inhibitors vs chemotherapy among patients who have metastatic colorectal cancer with high microsatellite instability, mismatch repair deficiency, and/or high tumor mutational burden. read more here.
Keywords: checkpoint inhibitors; immune checkpoint; metastatic colorectal; inhibitors chemotherapy ... See more keywords
Immune Checkpoint Inhibitors and Long-term Survival of Patients With Metastatic Urothelial Cancer
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.7444
Abstract: This cohort study uses published clinical trial data to assess long-term survival of patients with metastatic urothelial carcinoma who are treated with immune checkpoint inhibitors. read more here.
Keywords: long term; immune checkpoint; metastatic urothelial; term survival ... See more keywords
Encephalitis Induced by Immune Checkpoint Inhibitors: A Systematic Review.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2021.0249
Abstract: Importance Encephalitis is a severe immune-related adverse event secondary to treatment with immune checkpoint inhibitors (ICIs). The spectrum of ICI-induced encephalitis (ICI-iE) ranges from disease that resolves fully to lethal forms. Moreover, ICIs may unmask… read more here.
Keywords: immune checkpoint; checkpoint inhibitors; ici; prognosis ... See more keywords