Articles with "immune complex" as a keyword



Immune Complex Vaccination.

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Published in 2019 at "Current topics in microbiology and immunology"

DOI: 10.1007/82_2019_153

Abstract: Antibody/antigen binding results in immune complexes (IC) that have a variety of regulatory functions. One important feature is the enhanced host immune activation against antigen contained in the complex. ICs play important roles at several… read more here.

Keywords: immune; complex vaccination; immune complex; microbiology ... See more keywords

STK4 Deficiency in a Patient with Immune Complex Glomerulonephritis, Salt-Losing Tubulopathy, and Castleman’s-Like Disease

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Published in 2019 at "Journal of Clinical Immunology"

DOI: 10.1007/s10875-019-00682-9

Abstract: To the Editor: Combined immunodeficiency diseases (CID) are a heterogeneous group of disorders which all share profound T cell dysfunction. The presence of autologous T cells complicates diagnosis as these exhibit varying degrees of functionality,… read more here.

Keywords: salt losing; losing tubulopathy; castleman like; immune complex ... See more keywords

The immune complex transfer enzyme immunoassay: Mechanism of improved sensitivity compared with conventional sandwich enzyme immunoassay.

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Published in 2018 at "Journal of immunological methods"

DOI: 10.1016/j.jim.2018.05.010

Abstract: Immune complex transfer enzyme immunoassay (ICT-EIA) is one of the technologies which enables ultrasensitive measurements of protein biomarkers. The ICT-EIA uses two types of beads and sandwich-shaped immune complexes are transferred from the 1st bead… read more here.

Keywords: ict eia; complex transfer; transfer enzyme; immune complex ... See more keywords

Preclinical assessment of two FcγRI-specific antibodies that competitively inhibit immune complex-FcγRI binding to suppress autoimmune responses

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-65133-z

Abstract: Overactivation of FcγRI by immune complexes (IC) is implicated in various autoimmune disorders and neuropathies. Currently, no effective FcγRI-specific blocking antibodies are available. Here we report preclinical data revealing two anti-FcγRI antibodies, C01 and C04,… read more here.

Keywords: immune complex; c01 c04; autoimmune; assessment two ... See more keywords

Skin testing might have a diagnostic role in immune complex-mediated hypersensitivity reactions.

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Published in 2022 at "Clinical and experimental dermatology"

DOI: 10.1093/ced/llac003

Abstract: Clinical applications of skin testing are known to help diagnose IgE-mediated and T-cell-mediated delayed cutaneous reactions. By contrast, drug-induced immune complex-mediated vasculitis is primarily diagnosed based on medical history, clinical setting and laboratory evidence of… read more here.

Keywords: complex mediated; skin testing; immune complex; mediated hypersensitivity ... See more keywords

#1517 Glomerular immune complex deposits on electron microscopy in ANCA associated vasculitis: clinical and outcomes features

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Published in 2024 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfae069.395

Abstract: Glomerulonephritis related to antineutrophil cytoplasmic autoantibodies (ANCA) is typically referred to as “pauci-immune”, however, it is not unusual for kidney biopsies to exhibit some immune complex deposition within glomeruli on electron microscopic study. Such deposits… read more here.

Keywords: complex deposits; anca associated; immune complex; electron microscopy ... See more keywords
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IgA vasculitis and anti-GBM disease: two ends of a spectrum of immune complex vasculitis.

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Published in 2020 at "Rheumatology"

DOI: 10.1093/rheumatology/kez540

Abstract: Two immune complex vasculitides, IgA vasculitis (IgAV) and anti-GBM disease, represent polar extremes with regard to our understanding of disease pathogenesis, standardized management protocols and outcomes. This report compares our current approach to these uncommon… read more here.

Keywords: vasculitis; anti gbm; gbm disease; disease ... See more keywords

Analysis of the ZAR1 Immune Complex Reveals Determinants for Immunity and Molecular Interactions1[OPEN]

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Published in 2017 at "Plant Physiology"

DOI: 10.1104/pp.17.00441

Abstract: Deciphering the molecular interactions within the ZAR1-ZED1 immune complex that lead to the induction of plant immunity. Plants depend on innate immunity to prevent disease. Plant pathogenic bacteria, like Pseudomonas syringae and Xanthomonas campestris, use… read more here.

Keywords: immunity; plant; immune complex; zar1 ... See more keywords

Enhanced uptake of blood coagulation factor VIII containing immune complexes by antigen presenting cells

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Published in 2017 at "Journal of Thrombosis and Haemostasis"

DOI: 10.1111/jth.13570

Abstract: Essentials Anti‐factor (F) VIII antibody formation is a major complication in the treatment of hemophilia A. We investigated uptake of FVIII and FVIII immune complex by bone marrow derived dendritic cells. Immune complex formation increased… read more here.

Keywords: immune; uptake blood; factor viii; immune complex ... See more keywords

Kidney Transplantation in Children and Adolescents With C3 Glomerulopathy or Immune Complex Membranoproliferative Glomerulonephritis: An International Survey of Current Practice

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Published in 2025 at "Pediatric Transplantation"

DOI: 10.1111/petr.70048

Abstract: Approximately 50% of patients with chronic kidney disease due to C3 glomerulopathy (C3G) or primary immune‐complex membranoproliferative glomerulonephritis (IC‐MPGN) will require dialysis and/or kidney transplantation (KTx) within the first 10 years of disease onset. Currently, there… read more here.

Keywords: kidney transplantation; complex membranoproliferative; immune complex; membranoproliferative glomerulonephritis ... See more keywords

Morphological Changes in the Saw-Tooth Pattern of Cuticular Drusen Associated with Immune Complex-Mediated Membranous Proliferative Glomerulonephritis Type III: A Case Report

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Published in 2025 at "Case Reports in Ophthalmology"

DOI: 10.1159/000547059

Abstract: Abstract Introduction: Patients with membranoproliferative glomerulonephritis (MPGN) type III may exhibit the saw-tooth pattern of cuticular drusen. This study reports a four-and-a-half-year retrospective time-dependent observation of cuticular drusen associated with immune complex-mediated MPGN type III… read more here.

Keywords: complex mediated; type iii; cuticular drusen; immune complex ... See more keywords