Suppression of adenosine monophosphate-activated protein kinase selectively triggers apoptosis in activated T cells and ameliorates immune diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.04.038
Abstract: Deficient apoptosis of activated T cells can result in immunological disorders. Molecules associated with energy and metabolisms are suggested to be involved in pathogenesis of immune diseases, but remain uninvestigated. In the present study we… read more here.
Keywords: apoptosis activated; activated cells; monophosphate activated; adenosine monophosphate ... See more keywords
CP-25, a compound derived from paeoniflorin: research advance on its pharmacological actions and mechanisms in the treatment of inflammation and immune diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-020-00510-6
Abstract: Total glycoside of paeony (TGP) has been widely used to treat inflammation and immune diseases in China. Paeoniflorin (Pae) is the major active component of TGP. Although TGP has few adverse drug reactions, the slow… read more here.
Keywords: inflammation immune; treatment inflammation; inflammation; research advance ... See more keywords
BCG and protection against inflammatory and auto-immune diseases
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2017.1333906
Abstract: ABSTRACT Introduction: Bacillus Calmette-Guérin (BCG) is the only available vaccine against tuberculosis. Although its protective efficacy against pulmonary tuberculosis is still under debate, it provides protection against other mycobacterial diseases. BCG is also an effective… read more here.
Keywords: inflammatory auto; auto immune; bcg; immune diseases ... See more keywords
The tRNA‐associated dysregulation in immune responses and immune diseases
Sign Up to like & getrecommendations! Published in 2019 at "Acta Physiologica"
DOI: 10.1111/apha.13391
Abstract: Transfer RNA (tRNA), often considered as a housekeeping molecule, mainly participates in protein translation by transporting amino acids to the ribosome. Nevertheless, accumulating evidence has shown that tRNAs are closely related to various physiological and… read more here.
Keywords: immune; associated dysregulation; immune responses; trna associated ... See more keywords
Recent Advances in the Role of Arid5a in Immune Diseases and Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.827611
Abstract: AT-rich interactive domain 5a (Arid5a) is a nucleic acid binding protein. In this review, we highlight recent advances in the association of Arid5a with inflammation and human diseases. Arid5a is known as a protein that… read more here.
Keywords: advances role; immune diseases; diseases cancer; role arid5a ... See more keywords