Maximizing insights from monogenic immune disorders.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2021.09.008
Abstract: Monogenic immune disorders provide unprecedented insights into the consequences of disrupting single genes in humans, thereby informing our understanding of fundamental immune function and disease. Genomics has accelerated monogenic disease discovery while also revealing the… read more here.
Keywords: disease; maximizing insights; monogenic immune; immune disorders ... See more keywords
Mesenchymal stromal cell based therapies for the treatment of immune disorders: recent milestones and future challenges
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2020.1714587
Abstract: ABSTRACT Introduction: Mesenchymal stromal cells (MSCs) present unique immunomodulatory properties that make them promising candidates for the treatment of inflammatory and immune disorders. MSC-mediated immunomodulation is a complex combination of mechanisms, in which the secretome… read more here.
Keywords: mesenchymal stromal; stromal cell; based therapies; treatment ... See more keywords
Allergen immunotherapy, cancer, and immune disorders
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000858
Abstract: Purpose of review The purpose of this review is to provide an update on the intriguing relationships between allergies, allergen immunotherapy, cancer, and immune disorders. Allergic diseases and cancer are increasing in incidence and prevalence… read more here.
Keywords: immunotherapy cancer; cancer immune; immune disorders; allergen immunotherapy ... See more keywords
Cardiovascular Implications of Immune Disorders in Women
Sign Up to like & getrecommendations! Published in 2022 at "Circulation Research"
DOI: 10.1161/circresaha.121.319877
Abstract: Supplemental Digital Content is available in the text. Immune responses differ between men and women, with women at higher risk of developing chronic autoimmune diseases and having more robust immune responses to many viruses, including… read more here.
Keywords: implications immune; cardiovascular implications; disorders women; risk ... See more keywords
Therapeutic Potential of microRNA Against Th2-associated Immune Disorders.
Sign Up to like & getrecommendations! Published in 2021 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026621666210303150235
Abstract: MicroRNAs (miRNAs) are short ~18-22 nucleotide, single-stranded, non-coding RNA molecules playing a crucial role in regulating diverse biological processes, and are frequently dysregulated during disease pathogenesis. Thus, targeting miRNA could be a potential candidate for… read more here.
Keywords: th2 associated; associated immune; microrna th2; therapeutic potential ... See more keywords
Roles of BTLA in Immunity and Immune Disorders
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.654960
Abstract: B and T lymphocyte attenuator (BTLA) is one of the most important cosignaling molecules. It belongs to the CD28 superfamily and is similar to programmed cell death-1 (PD-1) and cytotoxic T lymphocyte associated antigen-4 (CTLA-4)… read more here.
Keywords: immunity immune; roles btla; immune disorders; btla immunity ... See more keywords
Editorial: alternative antigen processing and presentation in immune disorders
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.993393
Abstract: COPYRIGHT © 2022 Alvarez, Antón and James. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided… read more here.
Keywords: presentation immune; processing presentation; alternative antigen; antigen processing ... See more keywords
Moringa oleifera Lam and its Therapeutic Effects in Immune Disorders
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.566783
Abstract: Moringa oleifera Lam., a plant native to tropical forests of India, is characterized by its versatile application as a food additive and supplement therapy. Accumulating evidence shows that Moringa plays a critical role in immune-related… read more here.
Keywords: moringa oleifera; therapeutic effects; immune disorders; oleifera lam ... See more keywords
Cysteine Cathepsins as Therapeutic Targets in Immune Regulation and Immune Disorders
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11020476
Abstract: Cysteine cathepsins, as the most abundant proteases found in the lysosomes, play a vital role in several processes—such as protein degradation, changes in cell signaling, cell morphology, migration and proliferation, and energy metabolism. In addition… read more here.
Keywords: cathepsins therapeutic; cysteine cathepsins; immune disorders; targets immune ... See more keywords
Immune disorders in sepsis and their treatment as a significant problem of modern intensive care.
Sign Up to like & getrecommendations! Published in 2017 at "Postepy higieny i medycyny doswiadczalnej"
DOI: 10.5604/01.3001.0010.3849
Abstract: Despite the great advances in the treatment of sepsis over the past 20 years, sepsis remains the main cause of death in intensive care units. In the context of new possibilities of treating sepsis, a… read more here.
Keywords: sepsis; treatment; intensive care; disorders sepsis ... See more keywords