Understanding Immune Dynamics in Liver Transplant Through Mathematical Modeling
Sign Up to like & getrecommendations! Published in 2024 at "Bulletin of Mathematical Biology"
DOI: 10.1007/s11538-025-01480-8
Abstract: Liver transplant can be a life-saving procedure for patients with end-stage liver disease. With the introduction of modern immunosuppressive therapies, short-term survival has significantly improved. However, long-term survival has not substantially improved in decades. Consequently,… read more here.
Keywords: liver transplant; transplant mathematical; immune dynamics; model ... See more keywords
Impact of mild hyperthermia on tumor-immune dynamics explored through mathematical modeling.
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DOI: 10.1038/s41598-025-28719-7
Abstract: The immune system plays a vital role in cancer control, yet its efficacy is often compromised by tumor-induced immunosuppression. Moderate hyperthermia (\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$39-42^{\circ }$$\end{document}C) can enhance immune… read more here.
Keywords: tumor immune; immune dynamics; hyperthermia; tumor ... See more keywords
Human lymph node immune dynamics as driver of vaccine efficacy: an understudied aspect of immune responses.
Sign Up to like & getrecommendations! Published in 2022 at "Expert review of vaccines"
DOI: 10.1080/14760584.2022.2045198
Abstract: INTRODUCTION During the last century, changes in hygiene, sanitation, and the advent of childhood vaccination have resulted in profound reductions in mortality from infectious diseases. Despite this success, infectious diseases remain an enigmatic public health… read more here.
Keywords: human lymph; immune; infectious diseases; immune responses ... See more keywords
Modeling the Interplay Between Viral and Immune Dynamics in HIV: A Review and Mrgsolve Implementation and Exploration
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DOI: 10.1111/cts.70160
Abstract: Since its initial discovery, HIV has infected more than 70 million individuals globally, leading to the deaths of 35 million. At present, the annual number of deaths has significantly decreased due to 75% of HIV‐positive individuals being… read more here.
Keywords: interplay viral; modeling interplay; immune dynamics; exploration ... See more keywords
Immune dynamics in the CNS and its barriers during homeostasis and disease *
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DOI: 10.1111/imr.13066
Abstract: The central nervous system (CNS) has historically been viewed as an immunologically privileged site, but recent studies have uncovered a vast landscape of immune cells that reside primarily along its borders. While microglia are largely… read more here.
Keywords: immune dynamics; dynamics cns; barriers homeostasis; immune cells ... See more keywords
Virology and immune dynamics reveal high household transmission of ancestral SARS‐CoV‐2 strain
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Allergy and Immunology"
DOI: 10.1111/pai.13824
Abstract: Household studies are crucial for understanding the transmission of SARS‐CoV‐2 infection, which may be underestimated from PCR testing of respiratory samples alone. We aim to combine the assessment of household mitigation measures; nasopharyngeal, saliva, and… read more here.
Keywords: immune dynamics; virology; transmission; virology immune ... See more keywords
A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology.
Sign Up to like & getrecommendations! Published in 2025 at "Science translational medicine"
DOI: 10.1126/scitranslmed.adu6032
Abstract: Acute graft-versus-host disease (aGVHD) is a severe complication of allogeneic hematopoietic stem cell transplantation, driven by alloreactive donor T cells in the gut. However, the roles of additional donor and host cells in this process… read more here.
Keywords: disease; immune dynamics; spatial atlas; across individuals ... See more keywords
Abstract 4543: Local and systemic tumor-immune dynamics in metastatic cancer
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DOI: 10.1158/1538-7445.am2017-4543
Abstract: Despite decades of effort, most disseminated cancers remain incurable, and progression from localized to metastatic disease is largely responsible for cancer-related mortality. In metastatic disease, an ongoing battle between tumor and host occurs at each… read more here.
Keywords: disease; site; tumor immune; immune dynamics ... See more keywords
Abstract A007: Radiomics of anaplastic Wilms tumors: Unraveling oncogenic immune dynamics
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DOI: 10.1158/2326-6074.cimm25-a007
Abstract: This study investigates the intricate interplay between oncogenic pathways and the immune microenvironment in anaplastic Wilms tumors (AWTs) and explores its radiological implications. AWTs, characterized by complex genetic alterations including TP53 and CTNNB1 mutations, exhibit… read more here.
Keywords: wilms tumors; cancer; immune dynamics; radiomics anaplastic ... See more keywords
Image-based classification of lymphocyte subsets from routine blood smears reveals distinct immune dynamics after CAR-T infusion
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DOI: 10.1182/blood-2025-4354
Abstract: Background Chimeric antigen receptor T-cell (CAR-T) therapy is an established treatment for hematological malignancies, yet tools for immune monitoring remain limited. Current assays such as quantitative PCR and flow cytometry are costly and impractical for… read more here.
Keywords: immune dynamics; blood smears; infusion; car ... See more keywords
Immune dynamics shaping pre-metastatic and metastatic niches in liver metastases: from molecular mechanisms to therapeutic strategies
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DOI: 10.1186/s12943-024-02171-z
Abstract: Liver metastases are commonly detected in the advanced stages of various malignant tumors, representing a significant clinical challenge. Throughout the process of liver metastases formation, immune cells play a pivotal role, particularly in the pre-metastatic… read more here.
Keywords: pre metastatic; liver metastases; immune dynamics; metastatic metastatic ... See more keywords