Transitions of blood immune endotypes and improved outcome by anakinra in COVID-19 pneumonia: an analysis of the SAVE-MORE randomized controlled trial
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DOI: 10.1186/s13054-024-04852-z
Abstract: Endotype classification may guide immunomodulatory management of patients with bacterial and viral sepsis. We aimed to identify immune endotypes and transitions associated with response to anakinra (human interleukin 1 receptor antagonist) in participants in the… read more here.
Keywords: trial; immune endotypes; covid pneumonia; blood ... See more keywords
High-Dimensional Analysis Reveals Distinct Endotypes in Patients With Idiopathic Inflammatory Myopathies
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DOI: 10.3389/fimmu.2022.756018
Abstract: The idiopathic inflammatory myopathies (IIM) are a rare clinically heterogeneous group of conditions affecting the skin, muscle, joint, and lung in various combinations. While myositis specific autoantibodies are well described, we postulate that broader immune… read more here.
Keywords: dimensional analysis; immune endotypes; idiopathic inflammatory; iim patients ... See more keywords