An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.07.009
Abstract: Virulent pathogens often cause the release of host-derived damage-associated molecular patterns (DAMPs) from infected cells. During encounters with immune-evasive viruses that block inflammatory gene expression, preformed DAMPs provide backup inflammatory signals that ensure protective immunity.… read more here.
Keywords: branch signaling; virus replication; evasive virus; signaling pathway ... See more keywords
Immune evasive human islet-like organoids ameliorate diabetes
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DOI: 10.1038/s41586-020-2631-z
Abstract: Islets derived from stem cells hold promise as a therapy for insulin-dependent diabetes, but there remain challenges towards achieving this goal 1 – 6 . Here we generate human islet-like organoids (HILOs) from induced pluripotent… read more here.
Keywords: islet; human islet; islet like; like organoids ... See more keywords
Glioblastoma Embryonic-like Stem Cells Exhibit Immune-Evasive Phenotype.
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DOI: 10.3390/cancers14092070
Abstract: BACKGROUND Glioma stem cells (GSCs) have self-renewal and tumor-initiating capacities involved in drug resistance and immune evasion mechanisms in glioblastoma (GBM). METHODS Core-GSCs (c-GSCs) were identified by selecting cells co-expressing high levels of embryonic stem… read more here.
Keywords: glioblastoma; phenotype; immune evasive; gscs ... See more keywords