No evidence of immune exhaustion after repeated SARS-CoV-2 vaccination in vulnerable and healthy populations
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DOI: 10.1038/s41467-025-60216-3
Abstract: Frequent SARS-CoV-2 vaccination in vulnerable populations has raised concerns that this may contribute to T cell exhaustion, which could negatively affect the quality of immune protection. Herein, we examined the impact of repeated SARS-CoV-2 vaccination… read more here.
Keywords: sars cov; cov vaccination; vaccination; repeated sars ... See more keywords
Colorectal Cancer-Associated Immune Exhaustion Involves T and B Lymphocytes and Conventional NK Cells and Correlates With a Shorter Overall Survival
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.778329
Abstract: Colorectal cancer (CRC) is one of the most common cancer worldwide, with a growing impact on public health and clinical management. Immunotherapy has shown promise in the treatment of advanced cancers, but needs to be… read more here.
Keywords: expression; immune exhaustion; cell markers; exhaustion ... See more keywords
Osteomyelitis is associated with increased anti-inflammatory response and immune exhaustion
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DOI: 10.3389/fimmu.2024.1396592
Abstract: Introduction Osteomyelitis (OMS) is a bone infection causing bone pain and severe complications. A balanced immune response is critical to eradicate infection without harming the host, yet pathogens manipulate immunity to establish a chronic infection.… read more here.
Keywords: regulatory cells; response; infection; associated increased ... See more keywords
Multiplex Immunofluorescence Captures Progressive Immune Exhaustion with Advancing Penile Squamous Cell Cancer Stage
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DOI: 10.3390/cancers16020303
Abstract: Simple Summary Penile cancer is a rare and aggressive disease. Current treatment options when the cancer is locally advanced are suboptimal and potentially mutilating. Insight into the immune dysregulation necessary for the emergence of penile… read more here.
Keywords: cancer; penile squamous; multiplex immunofluorescence; cell ... See more keywords