Targeted Modulation of Redox and Immune Homeostasis in Acute Lung Injury Using a Thioether-Functionalized Dendrimer.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202402146
Abstract: Acute lung injury (ALI) is the pathophysiological precursor of acute respiratory distress syndrome. It is characterized by increased oxidative stress and exaggerated inflammatory response that disrupts redox reactions and immune homeostasis in the lungs, thereby… read more here.
Keywords: redox; homeostasis; immune homeostasis; dendrimer ... See more keywords
Exposure to multiple heavy metals associate with aberrant immune homeostasis and inflammatory activation in preschool children.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.127257
Abstract: Heavy metals generate adverse health effects by interfering with immune homeostasis and promoting inflammation in individuals. Our objective was to explore the induction of immune and inflammatory responses by multiple heavy metals in children living… read more here.
Keywords: inflammatory; immune homeostasis; heavy metals; multiple heavy ... See more keywords
ATP-dependent one-dimensional movement maintains immune homeostasis by suppressing spontaneous MDA5 filament assembly
Sign Up to like & getrecommendations! Published in 2025 at "Cell Research"
DOI: 10.1038/s41422-025-01183-8
Abstract: MDA5 is a RIG-I-like receptor (RLR) that recognizes viral double-stranded RNA (dsRNA) to initiate the innate immune response. Its activation requires filament formation along the dsRNA, which triggers the oligomerization of N-terminal caspase activation and… read more here.
Keywords: mda5; immune homeostasis; one dimensional; filament assembly ... See more keywords
Mouse enteric neurons control intestinal plasmacytoid dendritic cell function via serotonin-HTR7 signaling
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DOI: 10.1038/s41467-024-53545-2
Abstract: Serotonergic neurons in the central nervous system control behavior and mood, but knowledge of the roles of serotonergic circuits in the regulation of immune homeostasis is limited. Here, we employ mouse genetics to investigate the… read more here.
Keywords: neurons control; serotonergic neurons; immune homeostasis; plasmacytoid dendritic ... See more keywords
SESN1 negatively regulates STING1 to maintain innate immune homeostasis
Sign Up to like & getrecommendations! Published in 2025 at "Autophagy"
DOI: 10.1080/15548627.2025.2463148
Abstract: ABSTRACT STING1 is a central hub protein of CGAS-STING1 signaling which is important signaling axis to sense DNA for the host against pathogens infection through regulating type I interferon (IFN-I) production. However, excessive STING1 activation-induced… read more here.
Keywords: sting1 maintain; sting1; immune homeostasis; interferon ... See more keywords
NF-κB/Relish readjusts miR-100 expression and recovers immune homeostasis in Drosophila melanogaster.
Sign Up to like & getrecommendations! Published in 2024 at "Insect science"
DOI: 10.1111/1744-7917.13484
Abstract: The regulation and maintenance of immune homeostasis are essential for animal survival, but the molecular mechanisms are not fully understood. Here, we used the model organism Drosophila melanogaster to uncover a potential mechanism by which… read more here.
Keywords: expression; mir 100; immune homeostasis; drosophila melanogaster ... See more keywords
Immune homeostasis in health and disease
Sign Up to like & getrecommendations! Published in 2018 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12043
Abstract: The immune system is one of the most dynamic in our bodies. The mechanisms that maintain immune homeostasis must contend with the constant churn of cell proliferation and death across a myriad of lineages at… read more here.
Keywords: homeostasis; cell homeostasis; immune homeostasis; health disease ... See more keywords
Biomarkers of Airway Immune Homeostasis Differ Significantly with Generation of E-Cigarettes.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202202-0373oc
Abstract: RATIONALE Numerous studies have demonstrated that e-cigarettes can impact respiratory immune homeostasis; however, the extent of these effects remains an active area of investigation, and most previous studies were conducted with model systems or subjects… read more here.
Keywords: generation cigarette; cigarette users; immune homeostasis; 4th generation ... See more keywords
NingXueShengBan Decoction Regulates Immune Homeostasis by PI3 K/Akt/mTOR and TLR4/NF-κB Signaling Pathways in Immune Thrombocytopenia Patients
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DOI: 10.1177/1934578x241276960
Abstract: Objective Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease. The immune imbalance of T cells is an essential pathological mechanism of ITP, more specific, the balance of Effector T cells (Teff)/Regulatory T cell (Treg) maintains… read more here.
Keywords: decoction; akt mtor; immune homeostasis; pi3 akt ... See more keywords
Cross-kingdom dialogs in the gut: Integrating bacterial pathogens, helminths, and microbiota interactions for immune homeostasis
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DOI: 10.1371/journal.ppat.1013494
Abstract: The interactions between bacterial pathogens, helminths, and commensal microbiota in the gut form a complex ecological network that profoundly impacts host immunity and health. Pathogens employ strategies such as type VI secretion systems (T6SS) and… read more here.
Keywords: bacterial pathogens; homeostasis; pathogens helminths; immune homeostasis ... See more keywords
Vitamin D3 Supplementation Promotes Regulatory T-Cells to Maintain Immune Homeostasis After Surgery for Early Stages of Colorectal Cancer
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DOI: 10.21873/invivo.13078
Abstract: Abstract Background/Aim: Vitamin D3 (VD3) affects the regulation of the immune system, including the differentiation and function of regulatory T-cells (Tregs). Tregs play an important role in maintaining immune homeostasis in patients with colorectal cancer… read more here.
Keywords: treated group; immune homeostasis; vd3 treated; group ... See more keywords