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Published in 2023 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13598
Abstract: Immune checkpoint inhibitors have been approved for the treatment of advanced hepatocellular carcinoma (HCC). However, immunotherapy requires the identification of suitable biomarkers to guide treatment. The gene for rhomboid 5 homolog 2 (IRHom2), which encodes…
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Keywords:
hepatocellular carcinoma;
rhbdf2;
may potential;
gene ... See more keywords
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Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6786-5_23
Abstract: Microglia are the innate immune cells of the central nervous system (CNS) and play an important role in the maintenance of tissue homeostasis, providing neural support and neuroprotection. Microglia constantly survey their environment and quickly…
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Keywords:
immune infiltrates;
nervous system;
central nervous;
microglia immune ... See more keywords
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Published in 2017 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2017.10.011
Abstract: Osteosarcoma is a rare primary bone cancer characterized by cancer cells producing calcified osteoid extracellular matrix and inducing lung metastases with a high frequency. The local microenvironment defined several tumor niches controlling the tumor growth…
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Keywords:
immune;
contribution immune;
immune infiltrates;
osteosarcoma ... See more keywords
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Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106490
Abstract: BACKGROUND Glioma is the most lethal primary brain tumor. Lower-grade glioma (LGG) is the crucial pathological type of Glioma. Immune-infiltration of the tumor microenvironment positively associated with overall survival in LGG. SYT16 is a gene…
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Keywords:
immune infiltrates;
syt16 expression;
lgg;
analysis ... See more keywords
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Published in 2020 at "BioMed Research International"
DOI: 10.1155/2020/8024138
Abstract: Lung adenocarcinoma (LUAD) is a major pathological type of lung cancer. Understanding the mechanism of LUAD at the molecular level is important for a clinical decision. In this study, we use bioinformatic analysis to explore…
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Keywords:
lung adenocarcinoma;
immune infiltrates;
p4ha1;
survival ... See more keywords
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Published in 2021 at "Journal of Immunology Research"
DOI: 10.1155/2021/7753553
Abstract: Gasdermin B (GSDMB) is part of the gasdermin (GSDM) family, and they use varying means of domain interactions in molecules to adjust their pore-forming and lipid-binding actions. The GSDM family has roles in the regulation…
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Keywords:
analysis;
expression;
cell;
ccrcc ... See more keywords
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Published in 2022 at "International Journal of Genomics"
DOI: 10.1155/2022/2723264
Abstract: The extensive morbidity of colorectal cancer (CRC) and the inferior prognosis of terminal CRC urgently call for reliable prognostic biomarkers. For this, we identified 704 differentially expressed genes (DEGs) by intersecting three datasets, GSE41328, GSE37364,…
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Keywords:
il1rn prrx1;
analysis;
colorectal cancer;
gene ... See more keywords
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Published in 2022 at "Journal of Healthcare Engineering"
DOI: 10.1155/2022/3565676
Abstract: Background Signal regulatory protein alpha (SIRPA) is an inhibitory receptor expressed in macrophages and a potential therapeutic target in cancers. This study aims to investigate the functional role of SIRPA in esophageal carcinoma (ESCA). Methods…
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Keywords:
immune infiltrates;
expression;
esophageal carcinoma;
sirpa expression ... See more keywords
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Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/7267131
Abstract: Hepatocellular carcinoma (HCC) remains an incurable disease with a very poor clinical outcome. The purpose of this article was to investigate whether the expression or methylation of tetrapeptide repeat domain 36 (TTC36) could be used…
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Keywords:
hepatocellular carcinoma;
hcc;
ttc36;
expression ... See more keywords
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Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-129013
Abstract: Langerhans Cell Histiocytosis (LCH) is a myeloproliferative disorder, most common in children, with an incidence of approximately 5 cases per million children and 1/10,000 live births per year - similar to the frequency of Hodgkin's…
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Keywords:
langerhans cell;
immune infiltrates;
cell histiocytosis;
repertoire ... See more keywords
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Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-548
Abstract: BACKGROUND As an important member of the chemokines, CCL14 plays a vital role in cancer progression. However, the role of CCL14 in THCA has not been investigated. This study aimed to reveal the clinical significance…
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Keywords:
ccl14 thca;
ccl14;
ccl14 immune;
thca ... See more keywords