Articles with "immune infiltrates" as a keyword



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RHBDF2 is correlated with immune infiltrates in hepatocellular carcinoma and may have potential as a biomarker

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Published in 2023 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13598

Abstract: Immune checkpoint inhibitors have been approved for the treatment of advanced hepatocellular carcinoma (HCC). However, immunotherapy requires the identification of suitable biomarkers to guide treatment. The gene for rhomboid 5 homolog 2 (IRHom2), which encodes… read more here.

Keywords: hepatocellular carcinoma; rhbdf2; may potential; gene ... See more keywords
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Isolation of Microglia and Immune Infiltrates from Mouse and Primate Central Nervous System.

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Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-6786-5_23

Abstract: Microglia are the innate immune cells of the central nervous system (CNS) and play an important role in the maintenance of tissue homeostasis, providing neural support and neuroprotection. Microglia constantly survey their environment and quickly… read more here.

Keywords: immune infiltrates; nervous system; central nervous; microglia immune ... See more keywords
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The contribution of immune infiltrates and the local microenvironment in the pathogenesis of osteosarcoma.

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Published in 2017 at "Cellular immunology"

DOI: 10.1016/j.cellimm.2017.10.011

Abstract: Osteosarcoma is a rare primary bone cancer characterized by cancer cells producing calcified osteoid extracellular matrix and inducing lung metastases with a high frequency. The local microenvironment defined several tumor niches controlling the tumor growth… read more here.

Keywords: immune; contribution immune; immune infiltrates; osteosarcoma ... See more keywords
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SYT16 is a prognostic biomarker and correlated with immune infiltrates in glioma: A study based on TCGA data.

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Published in 2020 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2020.106490

Abstract: BACKGROUND Glioma is the most lethal primary brain tumor. Lower-grade glioma (LGG) is the crucial pathological type of Glioma. Immune-infiltration of the tumor microenvironment positively associated with overall survival in LGG. SYT16 is a gene… read more here.

Keywords: immune infiltrates; syt16 expression; lgg; analysis ... See more keywords
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Overexpression of P4HA1 Is Correlated with Poor Survival and Immune Infiltrates in Lung Adenocarcinoma

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Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/8024138

Abstract: Lung adenocarcinoma (LUAD) is a major pathological type of lung cancer. Understanding the mechanism of LUAD at the molecular level is important for a clinical decision. In this study, we use bioinformatic analysis to explore… read more here.

Keywords: lung adenocarcinoma; immune infiltrates; p4ha1; survival ... See more keywords
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Upregulated GSDMB in Clear Cell Renal Cell Carcinoma Is Associated with Immune Infiltrates and Poor Prognosis

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Published in 2021 at "Journal of Immunology Research"

DOI: 10.1155/2021/7753553

Abstract: Gasdermin B (GSDMB) is part of the gasdermin (GSDM) family, and they use varying means of domain interactions in molecules to adjust their pore-forming and lipid-binding actions. The GSDM family has roles in the regulation… read more here.

Keywords: analysis; expression; cell; ccrcc ... See more keywords
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IL1RN and PRRX1 as a Prognostic Biomarker Correlated with Immune Infiltrates in Colorectal Cancer: Evidence from Bioinformatic Analysis

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Published in 2022 at "International Journal of Genomics"

DOI: 10.1155/2022/2723264

Abstract: The extensive morbidity of colorectal cancer (CRC) and the inferior prognosis of terminal CRC urgently call for reliable prognostic biomarkers. For this, we identified 704 differentially expressed genes (DEGs) by intersecting three datasets, GSE41328, GSE37364,… read more here.

Keywords: il1rn prrx1; analysis; colorectal cancer; gene ... See more keywords
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High SIRPA Expression Predicts Poor Prognosis and Correlates with Immune Infiltrates in Patients with Esophageal Carcinoma

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Published in 2022 at "Journal of Healthcare Engineering"

DOI: 10.1155/2022/3565676

Abstract: Background Signal regulatory protein alpha (SIRPA) is an inhibitory receptor expressed in macrophages and a potential therapeutic target in cancers. This study aims to investigate the functional role of SIRPA in esophageal carcinoma (ESCA). Methods… read more here.

Keywords: immune infiltrates; expression; esophageal carcinoma; sirpa expression ... See more keywords
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Study on the Prognostic Values of TTC36 Correlated with Immune Infiltrates and Its Methylation in Hepatocellular Carcinoma

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Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/7267131

Abstract: Hepatocellular carcinoma (HCC) remains an incurable disease with a very poor clinical outcome. The purpose of this article was to investigate whether the expression or methylation of tetrapeptide repeat domain 36 (TTC36) could be used… read more here.

Keywords: hepatocellular carcinoma; hcc; ttc36; expression ... See more keywords
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TCR Repertoire Clonality Analysis and Transcriptome Analyses of Immune Infiltrates in Patients with Langerhans Cell Histiocytosis Can Define Prognostic Biomarkers for Future Therapeutic Development

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Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-129013

Abstract: Langerhans Cell Histiocytosis (LCH) is a myeloproliferative disorder, most common in children, with an incidence of approximately 5 cases per million children and 1/10,000 live births per year - similar to the frequency of Hodgkin's… read more here.

Keywords: langerhans cell; immune infiltrates; cell histiocytosis; repertoire ... See more keywords
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Chemokine CCL14 affected the clinical outcome and correlated with immune infiltrates in thyroid carcinoma.

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Published in 2022 at "Histology and histopathology"

DOI: 10.14670/hh-18-548

Abstract: BACKGROUND As an important member of the chemokines, CCL14 plays a vital role in cancer progression. However, the role of CCL14 in THCA has not been investigated. This study aimed to reveal the clinical significance… read more here.

Keywords: ccl14 thca; ccl14; ccl14 immune; thca ... See more keywords