Size and Charge Dual‐Switchable Nanoparticles for Achieving Chemosensitization and Immune Infiltration against Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202411643
Abstract: Pancreatic ductal adenocarcinoma (PDAC), one of the most challenging cancers, is uniquely characterized by a biological barrier composed of multiple components in the extracellular matrix, preventing penetration of chemotherapeutic agents and hindering clinical drug treatment.… read more here.
Keywords: ductal adenocarcinoma; immune infiltration; infiltration; charge ... See more keywords
Elevated expression of FREM1 in breast cancer indicates favorable prognosis and high‐level immune infiltration status
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3543
Abstract: Breast cancer (BC) poses one of the major threats to female's health worldwide. Immune infiltration in BC is a key representative of the tumor microenvironment and has been proven highly relevant for prognosis. The role… read more here.
Keywords: status; breast; expression; immune infiltration ... See more keywords
ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6044
Abstract: BACKGROUND Lung adenocarcinoma (LUAD) is a common subtype of non-small cell lung cancer with high morbidity and mortality rates and is usually detected at advanced stages because of the early onset of metastasis. Adenosine deaminase… read more here.
Keywords: lung adenocarcinoma; luad; immune infiltration; expression ... See more keywords
Fc receptor‐like A promotes malignant behavior in renal cell carcinoma and correlates with tumor immune infiltration
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Medicine"
DOI: 10.1002/cam4.70072
Abstract: Our study aims to investigate the mechanisms through which Fc receptor‐like A (FCRLA) promotes renal cell carcinoma (RCC) and to examine its significance in relation to tumor immune infiltration. read more here.
Keywords: tumor immune; receptor like; immune infiltration; cell carcinoma ... See more keywords
APOA1 as a Potential Therapeutic Target and Novel Biomarker in Lung Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.70142
Abstract: Apolipoprotein A1 (APOA1), the main structural protein of high‐density lipoprotein, has been implicated in cancer, but its role in lung adenocarcinoma (LUAD) remains unclear. Here, we integrate pan‐cancer and LUAD‐focused multi‐omics with patient‐serum validation, in‐vitro… read more here.
Keywords: lung; lung adenocarcinoma; immune infiltration; apoa1 potential ... See more keywords
BTN3A2 serves as a prognostic marker and favors immune infiltration in triple‐negative breast cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29485
Abstract: Immune infiltration is reported to be highly associated with tumor progress. Since butyrophilin subfamily 3 member A2 (BTN3A2) serves as a crucial mediator in immune activation, we aimed to investigate the correlation of BTN3A2 in… read more here.
Keywords: cancer; btn3a2; immune infiltration; breast cancer ... See more keywords
Downregulation of dermatopontin in cholangiocarcinoma cells suppresses CCL19 secretion of macrophages and immune infiltration
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-023-05532-1
Abstract: Objective The tumor microenvironment (TME) in cholangiocarcinoma (CHOL) is typically characterized by a low level of immune infiltration, which accounts for the dismal prognosis of this patient population. This study sought to investigate the mechanisms… read more here.
Keywords: immune infiltration; ccl19 secretion; dpt; chol ... See more keywords
Identifying the hub gene and immune infiltration of osteoarthritis by bioinformatical methods
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05311-0
Abstract: Nowadays, there are more and more people who have been diagnosed osteoarthritis (OA). However, due to the complex changes of OA, the treatment outcome is not very well. In order to improve this situation, I… read more here.
Keywords: hub gene; identifying hub; osteoarthritis; immune infiltration ... See more keywords
Letter to the editor comments on ʻPBK as a Novel Biomarker with Excellent Diagnostic and Prognostic Value in HCC Associated with Immune Infiltration and Methylationʼ
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Molecular Histology"
DOI: 10.1007/s10735-025-10651-9
Abstract: This manuscript presents a letter to the editor addressing the study by Lv et al. (J Mol Histol 56(2):129, 2025), which identifies PDZ-binding kinase (PBK) as a diagnostic and prognostic biomarker for hepatocellular carcinoma (HCC).… read more here.
Keywords: letter; infiltration methylation; immune infiltration; diagnostic prognostic ... See more keywords
Pathways‐ and epigenetic‐based assessment of relative immune infiltration in various types of solid tumors
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Cancer Research"
DOI: 10.1016/bs.acr.2019.01.003
Abstract: &NA; Recent clinical studies document the power of immunotherapy in treating subsets of patients with advanced cancers. In this context and with multiple cancer immunotherapeutics already evaluated in the clinic and a large number in… read more here.
Keywords: cancer; pathways epigenetic; cancer types; immune infiltration ... See more keywords
Analysis of genomics and immune infiltration patterns of epithelial-mesenchymal transition related to metastatic breast cancer to bone
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DOI: 10.1016/j.tranon.2020.100993
Abstract: Highlights • Differential expression analysis showed a total of 304 differentially expressed genes, which were mainly related to proteoglycans in cancer, the PI3K/Akt signaling pathway, and the TGF-beta signaling pathway.• The survival-related linear risk assessment… read more here.
Keywords: infiltration patterns; breast cancer; immune infiltration; cancer ... See more keywords