Construction of a cuproptosis‐related lncRNA signature for predicting prognosis and immune landscape in osteosarcoma patients
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5214
Abstract: Long noncoding RNAs (lncRNAs) influence the onset of osteosarcoma. Cuproptosis is a novel cell death mechanism. We attempted to identify a cuproptosis‐related lncRNA signature to predict the prognosis and immune landscape in osteosarcoma patients. read more here.
Keywords: related lncrna; cuproptosis; lncrna signature; immune landscape ... See more keywords
The prognostic effect of PNN in digestive tract cancers and its correlation with the tumor immune landscape in colon adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24327
Abstract: The present study investigated the expression, mutation, and methylation profile of PNN and its prognostic value in digestive tract cancers. The disparities in signaling pathways and the immune landscape in colon adenocarcinoma (COAD) based on… read more here.
Keywords: pnn; digestive tract; landscape colon; colon adenocarcinoma ... See more keywords
Immune landscape of viral cancers: Insights from single‐cell sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28348
Abstract: Viral infections trigger a wide range of immune responses thought to drive tumorigenesis and malignant progression. Dissecting virus‐induced changes in the tumor immune microenvironment (TIME) is therefore crucial to identify key leukocyte populations that may… read more here.
Keywords: cell; cell sequencing; single cell; immune landscape ... See more keywords
The Immune Landscape in Women Cancers.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer treatment and research"
DOI: 10.1007/978-3-030-38862-1_8
Abstract: In this chapter, we summarize the latest findings in the field of immuno-oncology of women cancers, particularly ovarian and breast tumors. We describe the relationship between immune parameters and clinical outcomes by evaluating the contribution… read more here.
Keywords: immune landscape; landscape women; women cancers; breast ... See more keywords
Comprehensive characterization of tumor immune landscape following oncolytic virotherapy by single-cell RNA sequencing
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-03084-2
Abstract: An important mechanism of oncolytic virotherapy in ameliorating cancer immunotherapy is by inducing significant changes in the immune landscape in the tumor microenvironment (TME). Despite this notion and the potential therapeutic implications, a comprehensive analysis… read more here.
Keywords: immune landscape; single cell; oncolytic virotherapy; virotherapy ... See more keywords
Understanding the impact of chemotherapy on the immune landscape of high-grade serous ovarian cancer
Sign Up to like & getrecommendations! Published in 2022 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2022.100926
Abstract: Highlights • Neoadjuvant chemotherapy induces heterogeneous changes in the tumor microenvironment.• Macrophages are a significant component of the TME PD-L1 expression enriched in a subset of patients.• Alteration in T cell ratios after chemotherapy indicate… read more here.
Keywords: chemotherapy immune; chemotherapy; impact chemotherapy; understanding impact ... See more keywords
An immune landscape based prognostic signature predicts the immune status and immunotherapeutic responses of patients with colorectal cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118368
Abstract: AIMS Colorectal cancer (CRC) is one of the most common cancers with poor prognosis worldwide. The advent of immunotherapy has greatly improved survival in refractory patients of CRC. In this study, we aimed to identify… read more here.
Keywords: prognostic signature; immunotherapeutic responses; crc; immune landscape ... See more keywords
Immune sunrise: from the immunome to the cancer immune landscape
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2021.2019896
Abstract: ABSTRACT The complex dynamics of the tumor-immune interaction during tumor progression have been characterized by integrating genomic and proteomic experiments. The Immunome, a reference compendium of markers for the majority of immune cell subpopulations was… read more here.
Keywords: immune sunrise; sunrise immunome; cancer; immune landscape ... See more keywords
NIMG-39. REVEALING THE TUMOR-IMMUNE LANDSCAPE THROUGH SPATIALLY-RESOLVED RADIOMICS: CASE STUDIES
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.709
Abstract: Conventional magnetic resonance imaging (MR) guides patient care in GBM. However, there is mounting awareness that MR enhancement is non-specific reflecting either tumor progression or non-tumoral inflammatory changes. Histological evaluation of GBM is held as… read more here.
Keywords: revealing tumor; landscape spatially; nimg revealing; tumor immune ... See more keywords
The immune landscape in BCR-ABL negative myeloproliferative neoplasms: inflammation, infections and opportunities for immunotherapy.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of haematology"
DOI: 10.1111/bjh.17850
Abstract: Breakpoint cluster region-Abelson (BCR-ABL) negative myeloproliferative neoplasms (MPNs) are chronic myeloid neoplasms initiated by the acquisition of gene mutation(s) in a haematopoietic stem cell, leading to clonal expansion and over-production of blood cells and their… read more here.
Keywords: negative myeloproliferative; inflammation; bcr abl; abl negative ... See more keywords
Characterizing the Molecular and Immune Landscape of Canine Bladder Cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary and comparative oncology"
DOI: 10.1111/vco.12740
Abstract: Transitional cell carcinoma (TCC), also known as urothelial carcinoma, is the most common bladder cancer in humans and dogs. Approximately one-quarter of human TCCs are muscle-invasive and associated with a high risk of death from… read more here.
Keywords: bladder cancer; bladder; ctcc tumors; immune landscape ... See more keywords