Navigating the diverse immune landscapes of psoriatic arthritis
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-021-00848-x
Abstract: The goal of remission in psoriatic arthritis (PsA) has remained elusive despite the influx of a range of new therapies over the last 20 years. In contrast, therapeutic responses to agents that inhibit IL-23 or… read more here.
Keywords: psoriatic arthritis; navigating diverse; immune landscapes; diverse immune ... See more keywords
The Genomic and Immune Landscapes of Lethal Metastatic Breast Cancer
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DOI: 10.1016/j.celrep.2019.04.098
Abstract: Summary The detailed molecular characterization of lethal cancers is a prerequisite to understanding resistance to therapy and escape from cancer immunoediting. We performed extensive multi-platform profiling of multi-regional metastases in autopsies from 10 patients with… read more here.
Keywords: immune landscapes; breast cancer; genomic immune; landscapes lethal ... See more keywords
Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms
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DOI: 10.1038/nm.4463
Abstract: Multiple immune-cell types can infiltrate tumors and promote progression and metastasis through different mechanisms, including immunosuppression. How distinct genetic alterations in tumors affect the composition of the immune landscape is currently unclear. Here, we characterized… read more here.
Keywords: immune landscapes; driven immune; diverse genetic; progression ... See more keywords
N6-methylandenosine-related immune genes correlate with prognosis and immune landscapes in gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1009881
Abstract: Objectives This study aimed to probe into the significance of N6-methyladenosine (m6A)-related immune genes (m6AIGs) in predicting prognoses and immune landscapes of patients with gastric cancer (GC). Methods The clinical data and transcriptomic matrix of… read more here.
Keywords: immune genes; risk; gastric cancer; related immune ... See more keywords
Identification of Novel Tumor Antigens and the Immune Landscapes of Bladder Cancer Patients for mRNA Vaccine Development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.921711
Abstract: Background mRNA vaccines are a novel technology that provide a potential strategy for cancer treatment. However, few studies exist that are focused on the application and development of mRNA vaccines in bladder cancer (BLCA). Therefore,… read more here.
Keywords: mrna vaccines; development; bladder cancer; immune landscapes ... See more keywords