Articles with "immune libraries" as a keyword



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Rapid Generation of Chicken Immune Libraries for Yeast Surface Display.

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Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9853-1_16

Abstract: Fluorescence-activated cell sorting (FACS) in combination with yeast surface display has emerged as a vital tool for the isolation and engineering of antibodies and antibody-derived fragments from synthetic, naïve, and immune libraries. However, the generation… read more here.

Keywords: generation; surface display; immune libraries; yeast surface ... See more keywords
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Streamlining the Transition From Yeast Surface Display of Antibody Fragment Immune Libraries to the Production as IgG Format in Mammalian Cells

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Published in 2022 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2022.794389

Abstract: Yeast-surface display (YSD) is commonly applied to screen Fab immune or naïve libraries for binders of predefined target molecules. However, reformatting of isolated variants represents a time-intensive bottleneck. Herein, we present a novel approach to… read more here.

Keywords: yeast surface; surface display; immune libraries; antibody ... See more keywords