Identification of Caveolae-Associated Protein 4 Autoantibodies as a Biomarker of Immune-Mediated Rippling Muscle Disease in Adults
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2022.1357
Abstract: Key Points Question Is there an autoantibody biomarker of immune-mediated rippling muscle disease (iRMD)? Findings In this cohort study, autoantibodies to caveolae-associated protein 4 (cavin-4) were identified and orthogonally validated in 8 of 10 patients… read more here.
Keywords: biomarker immune; disease; immune mediated; muscle ... See more keywords
Association of Trauma With Long-Term Risk of Death and Immune-Mediated or Cancer Disease in Same-Sex Twins.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA surgery"
DOI: 10.1001/jamasurg.2023.1560
Abstract: Importance Immediate consequences of trauma include a rapid and immense activation of the immune system, whereas long-term outcomes include premature death, physical disability, and reduced workability. Objective To investigate if moderate to severe trauma is… read more here.
Keywords: twin; trauma; mediated cancer; immune mediated ... See more keywords
Autologous Organoid‐T Cell Co‐Culture Platform for Modeling of Immune‐Mediated Drug‐Induced Liver Injury
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202508584
Abstract: Modeling adaptive immune responses in induced pluripotent stem cell (iPSC)‐derived liver systems remains a critical barrier for studying immune‐mediated hepatic diseases, including idiosyncratic drug‐induced liver injury (iDILI). Conventional hepatotoxicity models lack the components required to… read more here.
Keywords: immune mediated; culture; drug; cell ... See more keywords
Preventing infectious complications when treating non‐malignant immune‐mediated hematologic disorders
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25642
Abstract: Immunosuppressants, targeted antibody therapies, and surgical splenectomy are amongst the treatment choices for immune‐mediated non‐malignant hematologic disorders, with infection being the most common non‐hematological adverse event from these therapies. Corticosteroids are associated with a length‐of‐treatment… read more here.
Keywords: preventing infectious; hematologic disorders; complications treating; immune mediated ... See more keywords
Major adverse cardiovascular events in Survivors of Immune-mediated Thrombotic Thrombocytopenic Purpura.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of hematology"
DOI: 10.1002/ajh.26341
Abstract: Cardiovascular disease is a leading cause of death in survivors of immune-mediated thrombotic thrombocytopenic purpura (iTTP), but the epidemiology of major adverse cardiovascular events (MACE) in iTTP survivors is unknown. We evaluated the prevalence and… read more here.
Keywords: survivors immune; thrombotic thrombocytopenic; immune mediated; major adverse ... See more keywords
The Role of Chimeric Antigen Receptor T‐Cell Therapy in Immune‐Mediated Neurological Diseases
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DOI: 10.1002/ana.27029
Abstract: Despite the use of ‘high efficacy’ disease‐modifying therapies, disease activity and clinical progression of different immune‐mediated neurological diseases continue for some patients, resulting in accumulating disability, deteriorating social and mental health, and high economic cost… read more here.
Keywords: immune mediated; therapy; neurological diseases; mediated neurological ... See more keywords
siRNA‐based nanotherapeutics as emerging modalities for immune‐mediated diseases: A preliminary review
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11841
Abstract: Immune‐mediated diseases (IMDs) are chronic conditions that have an immune‐mediated etiology. Clinically, these diseases appear to be unrelated, but pathogenic pathways have been shown to connect them. While inflammation is a common occurrence in the… read more here.
Keywords: mediated diseases; review; based sirna; immune mediated ... See more keywords
The multiple faces of autoimmune/immune‐mediated myocarditis in children: a biopsy‐proven case series treated with immunosuppressive therapy
Sign Up to like & getrecommendations! Published in 2021 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13163
Abstract: The role of immunosuppressive therapy (IT) in paediatric autoimmune/immune‐mediated myocarditis remains poorly defined. To explore its role, we present a series of three consecutive paediatric patients with biopsy‐proven, virus negative, autoimmune/immune‐mediated myocarditis, with distinct clinical… read more here.
Keywords: immunosuppressive therapy; immune mediated; biopsy proven; mediated myocarditis ... See more keywords
Long‐term efficacy and safety of tailored immunosuppressive therapy in immune‐mediated biopsy‐proven myocarditis: A propensity‐weighted study
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.3220
Abstract: Standardized immunosuppressive therapy (IS) had been previously investigated in biopsy‐proven (BP) lymphocytic myocarditis with heart failure (HF). This study evaluated efficacy and safety of tailored IS in BP immune‐mediated myocarditis, irrespective of histology and clinical… read more here.
Keywords: immunosuppressive therapy; immune mediated; biopsy proven; safety tailored ... See more keywords
γδ T cells in immune‐mediated kidney disease
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DOI: 10.1002/eji.202451069
Abstract: Immune‐mediated kidney diseases, including glomerulonephritis (GN), represent a diverse spectrum of disorders characterized by inflammation within the glomerulus and other renal compartments. Despite recent advances, the immunopathogenesis of these diseases remains incompletely understood. Current therapeutic… read more here.
Keywords: immune mediated; mediated kidney; kidney disease; cell ... See more keywords
A Case of Immune‐Mediated Liver Injury Induced by Olaparib
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30119
Abstract: Immune-mediated drug-induced liver injury (IM-DILI) can be triggered by biologic agents, in addition to traditional drugs, including statins, minocycline, and nitrofurantoin. IM-DILI may be indistinguishable at presentation from autoimmune hepatitis (AIH) and cessation of the… read more here.
Keywords: case immune; injury induced; immune mediated; liver injury ... See more keywords