Identification of Caveolae-Associated Protein 4 Autoantibodies as a Biomarker of Immune-Mediated Rippling Muscle Disease in Adults
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2022.1357
Abstract: Key Points Question Is there an autoantibody biomarker of immune-mediated rippling muscle disease (iRMD)? Findings In this cohort study, autoantibodies to caveolae-associated protein 4 (cavin-4) were identified and orthogonally validated in 8 of 10 patients… read more here.
Keywords: biomarker immune; disease; immune mediated; muscle ... See more keywords
Association of Trauma With Long-Term Risk of Death and Immune-Mediated or Cancer Disease in Same-Sex Twins.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA surgery"
DOI: 10.1001/jamasurg.2023.1560
Abstract: Importance Immediate consequences of trauma include a rapid and immense activation of the immune system, whereas long-term outcomes include premature death, physical disability, and reduced workability. Objective To investigate if moderate to severe trauma is… read more here.
Keywords: twin; trauma; mediated cancer; immune mediated ... See more keywords
Preventing infectious complications when treating non‐malignant immune‐mediated hematologic disorders
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25642
Abstract: Immunosuppressants, targeted antibody therapies, and surgical splenectomy are amongst the treatment choices for immune‐mediated non‐malignant hematologic disorders, with infection being the most common non‐hematological adverse event from these therapies. Corticosteroids are associated with a length‐of‐treatment… read more here.
Keywords: preventing infectious; hematologic disorders; complications treating; immune mediated ... See more keywords
Major adverse cardiovascular events in Survivors of Immune-mediated Thrombotic Thrombocytopenic Purpura.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of hematology"
DOI: 10.1002/ajh.26341
Abstract: Cardiovascular disease is a leading cause of death in survivors of immune-mediated thrombotic thrombocytopenic purpura (iTTP), but the epidemiology of major adverse cardiovascular events (MACE) in iTTP survivors is unknown. We evaluated the prevalence and… read more here.
Keywords: survivors immune; thrombotic thrombocytopenic; immune mediated; major adverse ... See more keywords
siRNA‐based nanotherapeutics as emerging modalities for immune‐mediated diseases: A preliminary review
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DOI: 10.1002/cbin.11841
Abstract: Immune‐mediated diseases (IMDs) are chronic conditions that have an immune‐mediated etiology. Clinically, these diseases appear to be unrelated, but pathogenic pathways have been shown to connect them. While inflammation is a common occurrence in the… read more here.
Keywords: mediated diseases; review; based sirna; immune mediated ... See more keywords
The multiple faces of autoimmune/immune‐mediated myocarditis in children: a biopsy‐proven case series treated with immunosuppressive therapy
Sign Up to like & getrecommendations! Published in 2021 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13163
Abstract: The role of immunosuppressive therapy (IT) in paediatric autoimmune/immune‐mediated myocarditis remains poorly defined. To explore its role, we present a series of three consecutive paediatric patients with biopsy‐proven, virus negative, autoimmune/immune‐mediated myocarditis, with distinct clinical… read more here.
Keywords: immunosuppressive therapy; immune mediated; biopsy proven; mediated myocarditis ... See more keywords
A Case of Immune‐Mediated Liver Injury Induced by Olaparib
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DOI: 10.1002/hep.30119
Abstract: Immune-mediated drug-induced liver injury (IM-DILI) can be triggered by biologic agents, in addition to traditional drugs, including statins, minocycline, and nitrofurantoin. IM-DILI may be indistinguishable at presentation from autoimmune hepatitis (AIH) and cessation of the… read more here.
Keywords: case immune; injury induced; immune mediated; liver injury ... See more keywords
Psychiatric comorbidity in immune‐mediated inflammatory diseases
Sign Up to like & getrecommendations! Published in 2021 at "World Psychiatry"
DOI: 10.1002/wps.20873
Abstract: World Psychiatry 20:2 June 2021 into understanding the mechanisms underlying clinical features. For example, chronic stress, clinical depression, or a life-threatening traumatic experience that may lead to PTSD could profoundly dampen ventral vagal regulation of… read more here.
Keywords: ventral vagal; comorbidity immune; inflammatory diseases; psychiatric comorbidity ... See more keywords
Immune-mediated cytokine storm and its role in severe dengue
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-017-0625-1
Abstract: Dengue remains one of the most important mosquito-borne diseases worldwide. Infection with one of the serologically related dengue viruses (DENVs) can lead to a wide range of clinical manifestations and severity. Severe dengue is characterized… read more here.
Keywords: role severe; immune mediated; dengue; severe dengue ... See more keywords
IGRA testing in patients with immune-mediated inflammatory diseases: which factors influence the results?
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology International"
DOI: 10.1007/s00296-017-3852-9
Abstract: Diagnosis of latent tuberculosis infection in patients with immune-mediated inflammatory chronic diseases (IMIDs) can be challenged as diagnostic test reliability could be impaired by immunosuppression. We retrospectively analyzed the Quantiferon Gold-Test in-Tube (QFT-G-IT) results of… read more here.
Keywords: patients immune; qft results; indeterminate qft; immune mediated ... See more keywords
Pregnant women with immune mediated inflammatory diseases who discontinue biologics have higher rates of disease flare
Sign Up to like & getrecommendations! Published in 2022 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-022-06463-x
Abstract: Biologic agents have revolutionized treatment of immune mediated inflammatory diseases (IMIDs). However, despite the benefits of treatment, there is limited data on its use during pregnancy leading to significant variation in practices. We evaluated maternal,… read more here.
Keywords: pregnant women; exposure; pregnancy; immune mediated ... See more keywords