Systemic immune mediators reflect tumour‐infiltrating lymphocyte intensity and predict therapeutic response in triple‐negative breast cancer
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DOI: 10.1111/imm.13627
Abstract: Triple‐negative breast cancer (TNBC) is an aggressive form of breast cancer (BC). Neoadjuvant chemotherapy has proven efficacy in its treatment, and a pathological complete response (pCR) to therapy is predictive of improved long‐term survival. The… read more here.
Keywords: breast cancer; response; immune mediators; systemic immune ... See more keywords
Plasma proteomics reveals early, broad release of chemokine, cytokine, TNF, and interferon mediators following trauma with delayed increases in a subset of chemokines and cytokines in patients that remain critically ill
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1038086
Abstract: Severe injury is known to cause a systemic cytokine storm that is associated with adverse outcomes. However, a comprehensive assessment of the time-dependent changes in circulating levels of a broad spectrum of protein immune mediators… read more here.
Keywords: cytokine; immune mediators; injury; release ... See more keywords
Exploring Urinary Extracellular Vesicles and Immune Mediators as Biomarkers of Kidney Injury in COVID-19 Hospitalized Patients
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DOI: 10.3390/diagnostics12112600
Abstract: Kidney injury is an important outcome associated with COVID-19 severity. In this regard, alterations in urinary extracellular vesicles (uEVs) could be detected in the early phases of renal injury and may be reflective of the… read more here.
Keywords: extracellular vesicles; kidney injury; immune mediators; urinary extracellular ... See more keywords
Identifying Rare Genetic Variants of Immune Mediators as Risk Factors for Autism Spectrum Disorder
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DOI: 10.3390/genes13061098
Abstract: Autism spectrum disorder (ASD) affects more than 1% of children, and there is no viable pharmacotherapeutic agent to treat the core symptoms of ASD. Studies have shown that children with ASD show changes in their… read more here.
Keywords: genetic variants; variants immune; autism spectrum; immune mediators ... See more keywords
Responses of Humoral and Cellular Immune Mediators in BALB/c Mice to LipX (PE11) as Seed Tuberculosis Vaccine Candidates
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DOI: 10.3390/genes13111954
Abstract: A member of the pe/ppe gene family, lipX (pe11), is capable of directing persistent Mycobacterium tuberculosis and avoiding host immune responses. Some studies have indicated that LipX (PE11) can detect humoral antibodies in tuberculosis patients.… read more here.
Keywords: tuberculosis; seed; immune mediators; lipx pe11 ... See more keywords
Metformin Treatment of Hidradenitis Suppurativa: Effect on Metabolic Parameters, Inflammation, Cardiovascular Risk Biomarkers, and Immune Mediators
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24086969
Abstract: Hidradenitis suppurativa (HS) is a common cutaneous and systemic inflammatory disease with a significant impact on mental health and quality of life. It is associated with obesity, insulin resistance, metabolic syndrome, cardiovascular (CV) disease, and… read more here.
Keywords: immune mediators; risk biomarkers; risk; hidradenitis suppurativa ... See more keywords
Starting to have sexual intercourse is associated with increases in cervicovaginal immune mediators in young women: a prospective study and meta-analysis
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DOI: 10.7554/elife.78565
Abstract: Background: Adolescent girls and young women (AGYW) are at high risk of sexually transmitted infections (STIs). It is unknown whether beginning to have sexual intercourse results in changes to immune mediators in the cervicovaginal tract… read more here.
Keywords: meta analysis; immune mediators; sexual intercourse; first sex ... See more keywords