Modelling Immune Memory Development.
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin of mathematical biology"
DOI: 10.1007/s11538-021-00949-6
Abstract: The cellular adaptive immune response to influenza has been analyzed through several recent mathematical models. In particular, Zarnitsyna et al. (Front Immunol 7:1-9, 2016) show how central memory CD8+ T cells reach a plateau after… read more here.
Keywords: memory development; immune memory; immune response; modelling immune ... See more keywords
Long noncoding RNAs: Emerging players regulating innate immune memory in the red flour beetle.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2021.104304
Abstract: A variety of strategies have been evolved to eradicate invading microbes. Phagocytes have developed in vertebrates and invertebrates to confer a non-specific immune response to pathogens. Besides, vertebrates have evolved lymphocytes to develop memory cells… read more here.
Keywords: long noncoding; memory red; immune memory; noncoding rnas ... See more keywords
Measles erases immune 'memory' for other diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Nature"
DOI: 10.1038/d41586-019-03324-7
Abstract: Results from tests of unvaccinated children and monkeys come as measles cases spike around the world. Results from tests of unvaccinated children and monkeys come as measles cases spike around the world. read more here.
Keywords: erases immune; memory diseases; immune memory; measles erases ... See more keywords
Immune memory limits human longevity: the role of memory СD4+ T cells in age-related immune abnormalities
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2020.1745638
Abstract: ABSTRACT Introduction: With age, the proportion of memory T cells increases, while the proportion and number of naive T cell decreases. Memory T cells are more sensitive to antigenic stimulation and less dependent on co-stimulation… read more here.
Keywords: age related; memory cells; immune memory; cell ... See more keywords
Enhancing anti-tumor efficacy and immune memory by combining 3p-GPC-3 siRNA treatment with PD-1 blockade in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2021.2010894
Abstract: ABSTRACT Hepatocellular carcinoma (HCC) is associated with a high mortality rate and presents a major challenge for human health. Activation of multiple oncogenes has been reported to be strongly associated with the progression of HCC.… read more here.
Keywords: hepatocellular carcinoma; anti tumor; hcc; immune memory ... See more keywords
Innate immune memory in cardiometabolic disease.
Sign Up to like & getrecommendations! Published in 2023 at "Cardiovascular research"
DOI: 10.1093/cvr/cvad030
Abstract: Low-grade systemic inflammation is a key pathophysiological component of atherosclerotic cardiovascular disease (CVD), and long-term activation of myeloid cells is thought to be crucial for these effects. Obesity and associated metabolic complications including hyperglycaemia and… read more here.
Keywords: disease; immune memory; trained immunity; memory cardiometabolic ... See more keywords
Immune memory characteristics of innate lymphoid cells
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000540
Abstract: Purpose of review Immune memory is essential for host defense against invaders and it is also used as a basis for vaccine development. For these reasons, it is crucial to understand its molecular basis. In… read more here.
Keywords: memory characteristics; characteristics innate; immune memory; memory ... See more keywords
Persistence of HBsAg‐specific antibodies and immune memory two to three decades after hepatitis B vaccination in adults
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13125
Abstract: The duration of protection after hepatitis B vaccination is not exactly known. This phase IV study evaluated antibody persistence and immune memory 20‐30 years after adult immunization with recombinant hepatitis B vaccine (HBsAg vaccine, Engerix‐B)… read more here.
Keywords: hbsag specific; immune memory; hepatitis vaccination; memory ... See more keywords
Mycobacterium bovis BCG Given at Birth Followed by Inactivated Respiratory Syncytial Virus Vaccine Prevents Vaccine-Enhanced Disease by Promoting Trained Macrophages and Resident Memory T Cells
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.01764-22
Abstract: RSV is the leading cause of severe lower respiratory tract infection of infants. ERD, characterized by Th2-biased responses, inflammation, and poor immune memory, has been an obstacle to the development of safe and effective killed… read more here.
Keywords: bcg given; trained macrophages; immune memory; rsv ... See more keywords
Trained immunity: adaptation within innate immune mechanisms.
Sign Up to like & getrecommendations! Published in 2022 at "Physiological reviews"
DOI: 10.1152/physrev.00031.2021
Abstract: The mechanisms underlying innate immune memory have been extensively explored in the last decades but are in fact largely unknown. While the specificity of adaptive immune memory in vertebrates is ensured through the recombination of… read more here.
Keywords: immune memory; mechanisms trained; trained immunity; innate immune ... See more keywords
Molecular mechanisms of insect immune memory and pathogen transmission
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1010939
Abstract: Insect-borne diseases transmitted by mosquitoes, such as malaria, dengue, Zika, and lymphatic filariasis, remain among the most prevalent infectious diseases worldwide [1]. For example, the incidence of dengue infection has increased significantly in recent decades… read more here.
Keywords: insect immune; molecular mechanisms; immune memory; transmission ... See more keywords