Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202108084
Abstract: Immunotherapy has emerged as one of the most powerful anti‐cancer therapies but is stymied by the limits of existing preclinical models with respect to disease latency and reproducibility. Additionally, the influence of differing immune microenvironments… read more here.
Keywords: tumor; immunotherapy; tumor immune; immune microenvironment ... See more keywords
Tumor immune microenvironment in therapy‐naive esophageal adenocarcinoma could predict the nodal status
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5386
Abstract: Currently, preoperative staging of esophageal adenocarcinoma (EAC) has modest reliability and accuracy for pT and pN stages prediction, which heavily affects overall survival. The interplay among immune checkpoints, oncogenes, and intratumoral and peritumoral immune infiltrating… read more here.
Keywords: therapy naive; immune microenvironment; tumor immune; microenvironment therapy ... See more keywords
Genetic and immune microenvironment characterization of HER2‐positive gastric cancer: Their association with response to trastuzumab‐based treatment
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5769
Abstract: We aimed to determine the molecular and immune microenvironment characteristics of HER2‐positive gastric cancer (GC) related to the patient's response to first‐line trastuzumab‐based treatment. read more here.
Keywords: positive gastric; immune microenvironment; trastuzumab based; gastric cancer ... See more keywords
The exploration of new therapeutic targets for HPV‐negative head and neck squamous cell cancer through the construction of a ceRNA network and immune microenvironment analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29615
Abstract: Previous studies have shown that human papillomavirus (HPV)‐negative patients with head and neck squamous cell cancer (HNSCC) suffer from an unsatisfactory prognosis. Long noncoding RNAs (lncRNAs) have been verified to participate in many biological processes,… read more here.
Keywords: network; analysis; cerna network; immune microenvironment ... See more keywords
Adenylate kinase 2 is a biomarker related to the prognosis of glioma and the immune microenvironment.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24892
Abstract: BACKGROUND Among the brain and the other central nervous system, gliomas are the most prevalent malignant primary tumors. Adenylate kinase 2 (AK2) is generally thought to be crucial for energy metabolism and signal transduction. Several… read more here.
Keywords: immune microenvironment; expression; glioma; ak2 expression ... See more keywords
The neuro‐immune microenvironment of acupoints—initiation of acupuncture effectiveness
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ab0420-361rr
Abstract: Acupuncture is a centuried and unfading treatment of traditional Chinese medicine, which has been proved to exert curative effects on various disorders. Numerous works have been put in to uncover the effective mechanisms of acupuncture.… read more here.
Keywords: acupoints initiation; immune microenvironment; microenvironment; microenvironment acupoints ... See more keywords
Heterogeneity in the immune microenvironment of bone metastasis in driver-positive non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular carcinogenesis"
DOI: 10.1002/mc.23541
Abstract: Mutations in epidermal growth factor receptor and anaplastic lymphoma kinase are common driver events in non-small cell lung cancer (NSCLC), which are associated with a high frequency of bone metastases (BMs). While the bone marrow… read more here.
Keywords: cell; bms; immune microenvironment; bone ... See more keywords
Noninvasive evaluation of tumor immune microenvironment in patients with clear cell renal cell carcinoma using metabolic parameter from preoperative 2-[18F]FDG PET/CT
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-021-05399-9
Abstract: Nowadays, it is necessary to explore effective biomarkers associated with tumor immune microenvironment (TIME) noninvasively. Here, we investigated whether the metabolic parameter from preoperative 2-[18F]FDG PET/CT could provide information related to TIME in patients with… read more here.
Keywords: immune microenvironment; tumor immune; 18f fdg; fdg pet ... See more keywords
Identification of KRAS G12V associated clonal neoantigens and immune microenvironment in long-term survival of pancreatic adenocarcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-03012-4
Abstract: To investigate the molecular characteristics in tumor immune microenvironment that affect long-term survival of patients with pancreatic adenocarcinoma (PAAD). The tumor related genetic features of a female PAAD patient (over 13-year survival) who suffered from… read more here.
Keywords: long term; immune microenvironment; clonal neoantigens; term survival ... See more keywords
Targeting the tumour immune microenvironment for cancer therapy in human gastrointestinal malignancies.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2019.05.017
Abstract: Gastrointestinal (GI) cancer is a malignancy of the GI tract and accessory digestive organs. GI cancer patients develop resistance to chemotherapy, targeted therapy drugs and immune therapies. Although immune checkpoint inhibitors have shown promising clinical… read more here.
Keywords: therapy; time; tumour immune; immune microenvironment ... See more keywords
Genetic Alterations Impact Immune Microenvironment Interactions in Follicular Lymphoma.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer cell"
DOI: 10.1016/j.ccell.2020.04.008
Abstract: Interactions between germinal center B cells and immune cells in the microenvironment can play integral roles in transformation and growth of follicular lymphoma (FL). Three recent studies, two in this issue of Cancer Cell and… read more here.
Keywords: follicular lymphoma; genetic alterations; immune microenvironment; impact immune ... See more keywords