Ultrasound Tissue Engineering Technology for Regulating Immune Microenvironment
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DOI: 10.1002/adfm.202400656
Abstract: The immune microenvironment is critical for the occurrence, progression, and treatment of diseases. Ultrasound tissue engineering technology utilizes ultrasound and the principles of tissue engineering to repair, regenerate, and functionally reconstruct biological tissues. Ultrasound therapy… read more here.
Keywords: engineering technology; tissue engineering; microenvironment; ultrasound tissue ... See more keywords
Metabolic‐Efferocytosis Enabled Hydrogel Synergism Reprograms Immune Microenvironment for Promoting Diabetic Wound Repair
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202420079
Abstract: Diabetic wound healing remains a significant challenge, due to chronic inflammatory apoptotic cells accumulation. Herein, an immuno‐bioenergy regulated hydrogel (CCE) is reported, which converts apoptotic cells into cytokines that facilitate tissue repair. The CCE consisted… read more here.
Keywords: diabetic wound; repair; efferocytosis; citrate ... See more keywords
Ultrasmall Nanoparticles Regulate Immune Microenvironment by Activating IL‐33/ST2 to Alleviate Renal Ischemia‐Reperfusion Injury
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DOI: 10.1002/adhm.202303276
Abstract: Renal ischemia‐reperfusion injury (IRI) is a common disease with high morbidity and mortality. Renal IRI can cause the disorder of immune microenvironment and reprograming the immune microenvironment to alleviate excessive inflammatory response is crucial for… read more here.
Keywords: renal ischemia; ischemia reperfusion; iri; microenvironment ... See more keywords
Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening
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DOI: 10.1002/adma.202108084
Abstract: Immunotherapy has emerged as one of the most powerful anti‐cancer therapies but is stymied by the limits of existing preclinical models with respect to disease latency and reproducibility. Additionally, the influence of differing immune microenvironments… read more here.
Keywords: tumor; immunotherapy; tumor immune; immune microenvironment ... See more keywords
Synergistic Modulating of Mitochondrial Transfer and Immune Microenvironment to Attenuate Discogenic Pain
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DOI: 10.1002/advs.202500128
Abstract: Discogenic pain, caused by intervertebral disc degeneration (IVDD), is a prevalent and challenging condition to treat effectively. Macrophage infiltration with neural ectopic in‐growth resulting from structural disturbances within the intervertebral disc (IVD) is a major… read more here.
Keywords: pain; attenuate discogenic; discogenic pain; immune microenvironment ... See more keywords
Spatial Transcriptomics Reveals Transcriptomic and Immune Microenvironment Reprogramming during Thyroid Carcinoma Dedifferentiation
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DOI: 10.1002/advs.202506925
Abstract: Anaplastic thyroid carcinoma (ATC) is one of the most lethal human malignancies, often evolving from differentiated thyroid carcinoma (DTC) through a poorly understood dedifferentiation process. To elucidate this transition, spatial transcriptomic sequencing (spRNAseq) is performed… read more here.
Keywords: carcinoma; thyroid carcinoma; atc regions; immune microenvironment ... See more keywords
Lutetium‐Based Nanoprobes for Radiosensitization with Immune Microenvironment Remodeling and NIR‐II Fluorescence Imaging‐Guided Surgery in Colorectal Cancer
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DOI: 10.1002/advs.202510136
Abstract: Colorectal cancer (CRC) is among the top five leading cancers worldwide. Preoperative concurrent chemoradiotherapy is recommended for locally advanced CRC. Radiotherapy (RT), a traditional cancer treatment, not only controls local tumor growth but also potentially… read more here.
Keywords: colorectal cancer; cancer; nir fluorescence; crc ... See more keywords
Tumor immune microenvironment in therapy‐naive esophageal adenocarcinoma could predict the nodal status
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DOI: 10.1002/cam4.5386
Abstract: Currently, preoperative staging of esophageal adenocarcinoma (EAC) has modest reliability and accuracy for pT and pN stages prediction, which heavily affects overall survival. The interplay among immune checkpoints, oncogenes, and intratumoral and peritumoral immune infiltrating… read more here.
Keywords: therapy naive; immune microenvironment; tumor immune; microenvironment therapy ... See more keywords
Genetic and immune microenvironment characterization of HER2‐positive gastric cancer: Their association with response to trastuzumab‐based treatment
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DOI: 10.1002/cam4.5769
Abstract: We aimed to determine the molecular and immune microenvironment characteristics of HER2‐positive gastric cancer (GC) related to the patient's response to first‐line trastuzumab‐based treatment. read more here.
Keywords: positive gastric; immune microenvironment; trastuzumab based; gastric cancer ... See more keywords
Effective Antiviral Therapy Improves Immunosuppressive Activities in the Immune Microenvironment of Hepatocellular Carcinoma by Alleviating Inflammation and Fibrosis
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DOI: 10.1002/cam4.70459
Abstract: The immune microenvironment (IME) plays a crucial role in the progression of hepatocellular carcinoma (HCC). In HCC, the IME is often compromised by hepatitis B virus (HBV) infection, chronic inflammation, and fibrosis. Both antiviral therapy… read more here.
Keywords: hepatocellular carcinoma; inflammation fibrosis; inflammation; immune microenvironment ... See more keywords
The exploration of new therapeutic targets for HPV‐negative head and neck squamous cell cancer through the construction of a ceRNA network and immune microenvironment analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29615
Abstract: Previous studies have shown that human papillomavirus (HPV)‐negative patients with head and neck squamous cell cancer (HNSCC) suffer from an unsatisfactory prognosis. Long noncoding RNAs (lncRNAs) have been verified to participate in many biological processes,… read more here.
Keywords: network; analysis; cerna network; immune microenvironment ... See more keywords