Enhanced Immune Modulation and Bone Tissue Regeneration through an Intelligent Magnetic Scaffold Targeting Macrophage Mitochondria
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202500163
Abstract: During the bone tissue repair process, the highly dynamic interactions between the host and materials hinder precise, stable, and sustained immune modulation. Regulating the immune response based on potential mechanisms of macrophage phenotypic changes may… read more here.
Keywords: bone; macrophage; bone tissue; immune modulation ... See more keywords
The immune modulation effects of gemcitabine plus cisplatin induction chemotherapy in nasopharyngeal carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4705
Abstract: Studies are trying to add immunotherapy to gemcitabine and cisplatin (GP) induction chemotherapy, the standard therapy, in nasopharyngeal carcinoma (NPC) patients with locoregionally advanced disease. However, how the immune system responds to GP remains unknown. read more here.
Keywords: nasopharyngeal carcinoma; induction chemotherapy; immune modulation; cisplatin induction ... See more keywords
Immune modulation through secretory autophagy.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30427
Abstract: Autophagy is a central mechanism of cellular homeostasis through the degradation of a wide range of cellular constituents. However, recent evidence suggests that autophagy actively provides information to neighboring cells via a process called secretory… read more here.
Keywords: modulation secretory; secretory; secretory autophagy; homeostasis ... See more keywords
Immune Modulation in Heart Failure: the Promise of Novel Biologics
Sign Up to like & getrecommendations! Published in 2018 at "Current Treatment Options in Cardiovascular Medicine"
DOI: 10.1007/s11936-018-0617-z
Abstract: Purpose of reviewImmune system activation plays a central role in heart failure progression. Large-scale immune modulatory clinical trials targeting tumor necrosis factor-α and broad spectrum immune modulation have been negative. The objective of this review… read more here.
Keywords: clinical trials; heart; immune modulation; heart failure ... See more keywords
Immune modulation by a cellular network of mesenchymal stem cells and breast cancer cell subsets: Implication for cancer therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2017.07.011
Abstract: The immune modulatory properties of mesenchymal stem cells (MSCs) are mostly controlled by the particular microenvironment. Cancer stem cells (CSCs), which can initiate a clinical tumor, have been the subject of intense research. This review… read more here.
Keywords: immune modulation; cancer; modulation cellular; stem cells ... See more keywords
Mucin 1 antigen mimetic functionalized mannosylated peptide nanofibers for antigen uptake and immune modulation.
Sign Up to like & getrecommendations! Published in 2025 at "Biomaterials science"
DOI: 10.1039/d5bm00304k
Abstract: In this work, immune modulation of monocyte-derived dendritic cells was studied using in vitro cell culture and organ-on-chip models. Self-assembled mannosylated peptide nanofibers were prepared and integrated with the MUC1 TnThr mimetic Tn-MIM, to stimulate… read more here.
Keywords: antigen; peptide nanofibers; immune modulation; antigen mimetic ... See more keywords
Immune modulation by curcumin: The role of interleukin-10
Sign Up to like & getrecommendations! Published in 2019 at "Critical Reviews in Food Science and Nutrition"
DOI: 10.1080/10408398.2017.1358139
Abstract: ABSTRACT Cytokines are small secreted proteins released by different types of cells with specific effects on cellular signaling and communication via binding to their receptors on the cell surface. IL-10 is known to be a… read more here.
Keywords: immune modulation; disease; curcumin role; modulation curcumin ... See more keywords
OLMESARTAN FOR IMMUNE MODULATION AND ATTENUATION OF MYOCARDIAL FIBROSIS IN OBESITY-INDUCED CARDIAC DYSFUNCTION
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0001117136.51830.17
Abstract: Conclusions: Patients with exogenous constitutional obesity and arterial hypertension have complex disorders on the part of most systems, including changes in metabolism, lipid peroxidation, and the exchange of trace elements. read more here.
Keywords: olmesartan immune; modulation attenuation; myocardial fibrosis; obesity ... See more keywords
Insights into the Impact of CD8+ Immune Modulation on Human Immunodeficiency Virus Evolutionary Dynamics in Distinct Anatomical Compartments by Using Simian Immunodeficiency Virus-Infected Macaque Models of AIDS Progression
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.01162-17
Abstract: ABSTRACT A thorough understanding of the role of human immunodeficiency virus (HIV) intrahost evolution in AIDS pathogenesis has been limited by the need for longitudinally sampled viral sequences from the vast target space within the… read more here.
Keywords: immunodeficiency; immune modulation; infection; anatomical compartments ... See more keywords
The role of immune checkpoint molecules in PRRSV-2-induced immune modulation: insights from comparative in vivo evaluation including NADC34-like PRRSV
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Virology"
DOI: 10.1128/jvi.02298-24
Abstract: ABSTRACT The emergence of genetically diverse PRRSV-2 lineages, including the NADC34-like virus, presents significant challenges to the swine industry due to their variable pathogenicity and impact on immune modulation. However, the precise mechanisms underlying virus-induced… read more here.
Keywords: immune modulation; expression; nadc34 like; prrsv ... See more keywords
Abstract 6705: An integratedin vitroandin vivoapproach providing insights in immune modulation
Sign Up to like & getrecommendations! Published in 2020 at "Immunology"
DOI: 10.1158/1538-7445.am2020-6705
Abstract: In order to exploit the complex tumour microenvironment, immunoreactivity in a multitude of cell-based assays is required to predict mode of action (MOA), pharmacodynamics, and efficacy downstream. We have developed an integrated approach starting with… read more here.
Keywords: insights immune; immune modulation; target; oncology ... See more keywords