The immune modulation effects of gemcitabine plus cisplatin induction chemotherapy in nasopharyngeal carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4705
Abstract: Studies are trying to add immunotherapy to gemcitabine and cisplatin (GP) induction chemotherapy, the standard therapy, in nasopharyngeal carcinoma (NPC) patients with locoregionally advanced disease. However, how the immune system responds to GP remains unknown. read more here.
Keywords: nasopharyngeal carcinoma; induction chemotherapy; immune modulation; cisplatin induction ... See more keywords
Immune modulation through secretory autophagy.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30427
Abstract: Autophagy is a central mechanism of cellular homeostasis through the degradation of a wide range of cellular constituents. However, recent evidence suggests that autophagy actively provides information to neighboring cells via a process called secretory… read more here.
Keywords: modulation secretory; secretory; secretory autophagy; homeostasis ... See more keywords
Immune Modulation in Heart Failure: the Promise of Novel Biologics
Sign Up to like & getrecommendations! Published in 2018 at "Current Treatment Options in Cardiovascular Medicine"
DOI: 10.1007/s11936-018-0617-z
Abstract: Purpose of reviewImmune system activation plays a central role in heart failure progression. Large-scale immune modulatory clinical trials targeting tumor necrosis factor-α and broad spectrum immune modulation have been negative. The objective of this review… read more here.
Keywords: clinical trials; heart; immune modulation; heart failure ... See more keywords
Immune modulation by a cellular network of mesenchymal stem cells and breast cancer cell subsets: Implication for cancer therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2017.07.011
Abstract: The immune modulatory properties of mesenchymal stem cells (MSCs) are mostly controlled by the particular microenvironment. Cancer stem cells (CSCs), which can initiate a clinical tumor, have been the subject of intense research. This review… read more here.
Keywords: immune modulation; cancer; modulation cellular; stem cells ... See more keywords
Immune modulation by curcumin: The role of interleukin-10
Sign Up to like & getrecommendations! Published in 2019 at "Critical Reviews in Food Science and Nutrition"
DOI: 10.1080/10408398.2017.1358139
Abstract: ABSTRACT Cytokines are small secreted proteins released by different types of cells with specific effects on cellular signaling and communication via binding to their receptors on the cell surface. IL-10 is known to be a… read more here.
Keywords: immune modulation; disease; curcumin role; modulation curcumin ... See more keywords
Insights into the Impact of CD8+ Immune Modulation on Human Immunodeficiency Virus Evolutionary Dynamics in Distinct Anatomical Compartments by Using Simian Immunodeficiency Virus-Infected Macaque Models of AIDS Progression
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.01162-17
Abstract: ABSTRACT A thorough understanding of the role of human immunodeficiency virus (HIV) intrahost evolution in AIDS pathogenesis has been limited by the need for longitudinally sampled viral sequences from the vast target space within the… read more here.
Keywords: immunodeficiency; immune modulation; infection; anatomical compartments ... See more keywords
Abstract 6705: An integratedin vitroandin vivoapproach providing insights in immune modulation
Sign Up to like & getrecommendations! Published in 2020 at "Immunology"
DOI: 10.1158/1538-7445.am2020-6705
Abstract: In order to exploit the complex tumour microenvironment, immunoreactivity in a multitude of cell-based assays is required to predict mode of action (MOA), pharmacodynamics, and efficacy downstream. We have developed an integrated approach starting with… read more here.
Keywords: insights immune; immune modulation; target; oncology ... See more keywords
Abstract 2421: WST-11 vascular-targeted photodynamic therapy induced immune modulation in upper tract urothelial cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2421
Abstract: Introduction: Vascular-targeted photodynamic therapy (VTP) with the photosensitizing agent padeliporfin (WST-11/TOOKAD Soluble; STEBA Biotech) has been approved for treating men with low-risk prostate cancer. A phase 1 trial of VTP evaluating treatment of upper tract… read more here.
Keywords: vtp; upper tract; treatment; cancer ... See more keywords
Immune Modulation in Chronic Respiratory Diseases: The Path to Precision Medicine
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DOI: 10.1159/000509648
Abstract: In the last 50 years, there have been major advances in the understanding of the pathophysiology and, more recently, the pathobiology of chronic respiratory diseases. A deeper understanding of the immune system has significantly advanced… read more here.
Keywords: medicine; immune modulation; disease; respiratory diseases ... See more keywords
Immune Modulation in Lung Cancer: Current Concepts and Future Strategies
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DOI: 10.1159/000510385
Abstract: Cancer immunotherapy represents the most dynamic field of biomedical research currently, with thoracic immuno-oncology as a forerunner. PD-(L)1 inhibitors are already part of standard first-line treatment for both non-small-cell and small-cell lung cancer, while unprecedented… read more here.
Keywords: cell; immune modulation; lung cancer; cancer ... See more keywords
Immune modulation after Toca 511 and Toca FC treatment of colorectal cancer patients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.4_suppl.186
Abstract: 186Background: Toca 511 (vocimagene amiretrorepvec) is a cancer-selective, retroviral replicating vector encoding yeast cytosine deaminase that converts 5-fluorocytosine (5-FC) into 5-fluorouracil ... read more here.
Keywords: modulation toca; immune modulation; toca 511; 511 toca ... See more keywords