Pharmaco-Immunomodulatory Therapy in COVID-19
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DOI: 10.1007/s40265-020-01367-z
Abstract: The severe acute respiratory syndrome coronavirus 2 associated coronavirus disease 2019 (COVID-19) illness is a syndrome of viral replication in concert with a host inflammatory response. The cytokine storm and viral evasion of cellular immune… read more here.
Keywords: cytokine storm; covid; pharmaco immunomodulatory; immunomodulatory therapy ... See more keywords
Estimating the impact of biosimilar entry on prices and expenditures in rheumatoid arthritis: a case study of targeted immune modulators
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DOI: 10.1080/13696998.2022.2113252
Abstract: Abstract Objective To model changes in prices, utilization, and expenditures of targeted immune modulators (TIMs) for rheumatoid arthritis, accounting for biosimilar entry. Methods Using IQVIA National Sales Perspective data between 2013 and 2019, we examined… read more here.
Keywords: entry; targeted immune; immune modulators; exclusivity milestones ... See more keywords
Anthelmintic Drugs as Emerging Immune Modulators in Cancer
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DOI: 10.3390/ijms24076446
Abstract: Despite recent advances in treatment approaches, cancer is still one of the leading causes of death worldwide. Restoration of tumor immune surveillance represents a valid strategy to overcome the acquired resistance and cytotoxicity of conventional… read more here.
Keywords: emerging immune; modulators cancer; immune modulators; anthelmintic drugs ... See more keywords
Polysaccharides—Naturally Occurring Immune Modulators
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DOI: 10.3390/polym15102373
Abstract: The prevention of disease and infection requires immune systems that operate effectively. This is accomplished by the elimination of infections and abnormal cells. Immune or biological therapy treats disease by either stimulating or inhibiting the… read more here.
Keywords: immune modulators; occurring immune; naturally occurring; polysaccharides naturally ... See more keywords
Combination of Innate Immune Modulators as Vaccine Adjuvants in Mice
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DOI: 10.3390/vaccines8040569
Abstract: The development of new, effective, and safe vaccines necessarily requires the identification of new adjuvant(s) to enhance the potency and longevity of antigen-specific immune responses. In the present study, we compare the antibody-mediated and cell-mediated… read more here.
Keywords: modulators vaccine; arc4 arc7; vaccine adjuvants; combination innate ... See more keywords
Role of relevant immune-modulators and cytokines in hepatocellular carcinoma and premalignant hepatic lesions
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DOI: 10.3748/wjg.v24.i11.1228
Abstract: AIM To assess the levels of different immune modulators in patients with hepatocellular carcinoma (HCC), in relation to other hepatic diseases. METHODS Eighty-eight patients were included in the current study and represented patients with HCC… read more here.
Keywords: hepatocellular carcinoma; mdcs cd1c; cells cd56; hcc patients ... See more keywords
Role of inflammasome regulation on immune modulators
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DOI: 10.7555/jbr.32.20170120
Abstract: Inflammatory responses are essential in eliminating harmful substrates from damaged tissue and inducing recovery. Several cytokines participate in and facilitate this response. Certain cytokines such as interleukin (IL)-1β and IL-18 are initially produced in precursor… read more here.
Keywords: production; inflammasome regulation; regulation immune; role inflammasome ... See more keywords