Bayesian analysis of cytokines and chemokine identifies immune pathways of HBsAg loss during chronic hepatitis B treatment
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-86836-5
Abstract: Our objective was to examine differences in cytokine/chemokine response in chronic hepatitis B(CHB) patients to understand the immune mechanism of HBsAg loss (functional cure) during antiviral therapy. We used an unbiased machine learning strategy to… read more here.
Keywords: immune pathways; hbsag loss; analysis; treatment ... See more keywords
Differential immune pathways in classic and mixed variants of anaplastic thyroid cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e18579
Abstract: e18579Background: Patients with anaplastic thyroid cancer (ATC) have poor outcomes due to treatment resistance with an estimated 5-year survival rate of 7%. Although “classic” ATC can arise de novo... read more here.
Keywords: anaplastic thyroid; immune pathways; pathways classic; thyroid cancer ... See more keywords
An in vitro study to elucidate the effects of Septilin TM on immune pathways
Sign Up to like & getrecommendations! Published in 2018 at "Bangladesh Journal of Medical Science"
DOI: 10.3329/bjms.v17i2.35877
Abstract: Objective: The use of herbal immunomodulatory preparations to prevent and treat immunological complications is increasing in popularity. Rigorous in vitro, in vivo and clinical trial studies are needed to ensure safety, quality and efficacy for… read more here.
Keywords: effects septilin; immune pathways; across concentrations; unstimulated wbc ... See more keywords
Dysregulation of Placental Functions and Immune Pathways in Complete Hydatidiform Moles
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DOI: 10.3390/ijms20204999
Abstract: Gene expression studies of molar pregnancy have been limited to a small number of candidate loci. We analyzed high-dimensional RNA and protein data to characterize molecular features of complete hydatidiform moles (CHMs) and corresponding pathologic… read more here.
Keywords: immune pathways; complete hydatidiform; placental functions; dysregulation placental ... See more keywords
A Chemical Proteomics Approach to Discover Regulators of Innate Immune Signaling
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DOI: 10.3390/v15051112
Abstract: Innate immune pathways are tightly regulated to balance an appropriate response to infectious agents and tolerable levels of inflammation. Dysregulation of innate immune pathways can lead to severe autoinflammatory disorders or susceptibility to infections. Here,… read more here.
Keywords: immune pathways; proteomics approach; kinase inhibitors; innate immune ... See more keywords