Multi-omics data identified TP53 and LRP1B as key regulatory gene related to immune phenotypes via EPCAM in HCC.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer medicine"
DOI: 10.1002/cam4.4594
Abstract: BACKGROUND Many studies showed that the prognosis of hepatocellular carcinoma (HCC) was significantly associated with the expressions of TP53 and LRP1B. However, the potential influence of the two genes on the malignant progression of HCC… read more here.
Keywords: analysis; multi omics; hcc; gene ... See more keywords
Integrative Analysis of Multi-omics Data Identified EGFR and PTGS2 as Key Nodes in a Gene Regulatory Network Related to Immune Phenotypes in Head and Neck Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-19-3997
Abstract: Purpose: Malignant progression exhibits a tightly orchestrated balance between immune effector response and tolerance. However, underlying molecular principles that drive the establishment and maintenance of the tumor immune phenotype remain to be elucidated. Experimental Design:… read more here.
Keywords: related immune; immune phenotypes; gene; integrative analysis ... See more keywords
Understanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistry
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-017-1311-8
Abstract: BackgroundUnderstanding immune phenotypes and human gastric disease in situ requires an approach that leverages multiplexed immunohistochemistry (mIHC) with multispectral imaging to facilitate precise image analyses.MethodsWe developed a novel 4-color mIHC assay based on tyramide signal… read more here.
Keywords: gastric disease; immune phenotypes; disease; phenotypes human ... See more keywords
Distinct Immune Phenotypes in Infants Developing Asthma During Childhood
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DOI: 10.1542/peds.2020-023861hhh
Abstract: AH Thysen, J Waage, JM Larsen. Sci Transl Med. 2020;12(529):eaaw0258 To address whether a deregulated immune response to generic microbial exposures in infancy is associated with later development of asthma. In this population-based birth cohort,… read more here.
Keywords: distinct immune; phenotypes infants; asthma childhood; immune phenotypes ... See more keywords
Immune phenotypes in lung cancer patients with COPD: potential implications for immunotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2018.06.143
Abstract: Lung cancer remains one of the most commonly diagnosed neoplasms, being responsible for the majority of cancer-related deaths worldwide (1,2). Chronic obstructive pulmonary disease (COPD) is also a major cause of morbidity and mortality globally.… read more here.
Keywords: patients copd; immune phenotypes; phenotypes lung; lung cancer ... See more keywords
Bovine Peripheral Blood Derived Lymphocyte Proteome and Secretome Show Divergent Reaction of Bovine Immune Phenotypes after Stimulation with Pokeweed Mitogen
Sign Up to like & getrecommendations! Published in 2022 at "Proteomes"
DOI: 10.3390/proteomes10010007
Abstract: We recently identified a deviant bovine immune phenotype characterized by hyperproliferation of lymphocytes after polyclonal stimulation. This phenotype was first discovered in dams that responded to PregSure BVD vaccination by producing pathological antibodies, triggering the… read more here.
Keywords: bovine immune; pokeweed mitogen; immune phenotypes; stimulation ... See more keywords