Somatic-Immune Cells Crosstalk In-The-Making of Testicular Immune Privilege
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-021-00721-0
Abstract: Immunological infertility contributes significantly to the etiology of idiopathic male infertility. Shielding the spermatogenic cells from systemic immune responses is fundamental to secure normal production of spermatozoa. The body’s immune system is tuned with the… read more here.
Keywords: immune cells; immune privilege; testicular immune; somatic immune ... See more keywords
Uterine epithelial expression of the tumor necrosis factor superfamily: a strategy for immune privilege during pregnancy in a true epitheliochorial placentation species
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz233
Abstract: Abstract The maternal immune system tolerates semi-allogeneic placental tissues during pregnancy. Fas ligand (FASLG) and tumor necrosis factor superfamily 10 (TNFSF10) are known to be components of maternal immune tolerance in humans and mice. However,… read more here.
Keywords: immune privilege; pregnancy; conceptus; tnfsf10 ... See more keywords
Ocular immune privilege and retinal pigment epithelial cells.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiac016
Abstract: The ocular tissue microenvironment is immune-privileged and uses multiple immunosuppressive mechanisms to prevent the induction of inflammation. The retinal pigment epithelium plays an essential role in ocular immune privilege. In addition to serving as a… read more here.
Keywords: pigment; immune privilege; pigment epithelium; retinal pigment ... See more keywords
Pancreatic islets engineered with a FasL protein induce systemic tolerance at the induction phase that evolves into long‐term graft‐localized immune privilege
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Transplantation"
DOI: 10.1111/ajt.15747
Abstract: We have previously shown that pancreatic islets engineered to transiently display a modified form of FasL protein (SA‐FasL) on their surface survive indefinitely in allogeneic recipients without a need for chronic immunosuppression. Mechanisms that confer… read more here.
Keywords: protection; immune privilege; phase; fasl protein ... See more keywords
Immune privilege of skin stem cells: What do we know and what can we learn?
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Dermatology"
DOI: 10.1111/exd.14221
Abstract: The skin forms a barrier that prevents dehydration and keeps us safe from pathogens. To ensure proper function, the skin possesses a myriad of stem cell populations that are essential for maintenance and repair upon… read more here.
Keywords: skin stem; immune privilege; skin; stem ... See more keywords
Network meta‐analysis on the efficacy and safety of upadacitinib in adolescents and adults with moderate‐to‐severe atopic dermatitis
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Dermatology"
DOI: 10.1111/ijd.15850
Abstract: higher prevalence of smokers among patients with AA. Meta-analysis showed an association between ever smoking and AA, with a pooled OR of 1.12 (95% CI 1.10–1.14), Figure 1. Heterogeneity across studies was I = 48%.… read more here.
Keywords: analysis; hair; immune privilege; hair follicle ... See more keywords
Central nervous system zoning: How brain barriers establish subdivisions for CNS immune privilege and immune surveillance.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of internal medicine"
DOI: 10.1111/joim.13469
Abstract: The central nervous system (CNS) coordinates all our body functions. Neurons in the CNS parenchyma achieve this computational task by high speed communication via electrical and chemical signals and thus rely on a strictly regulated… read more here.
Keywords: system; cns immune; brain barriers; cns parenchyma ... See more keywords
A Fresh Glimpse into Cartilage Immune Privilege
Sign Up to like & getrecommendations! Published in 2022 at "Cartilage"
DOI: 10.1177/19476035221126349
Abstract: The increasing prevalence of degenerative cartilage disorders in young patients is a growing public concern worldwide. Cartilage’s poor innate regenerative capacity has inspired the exploration and development of cartilage replacement treatments such as tissue-engineered cartilages… read more here.
Keywords: fresh glimpse; cartilage; immune privilege; privilege ... See more keywords
Regulatory T Cells in Autoimmune Vasculitis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.844300
Abstract: Blood vessels are indispensable for host survival and are protected from inappropriate inflammation by immune privilege. This protection is lost in patients with autoimmune vasculitides, a heterogeneous group of diseases causing damage to arteries, arterioles,… read more here.
Keywords: cells autoimmune; immune privilege; regulatory cells; autoimmune vasculitis ... See more keywords
Photoreceptor Cells Constitutively Express IL-35 and Promote Ocular Immune Privilege
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158156
Abstract: Interleukin-27 is constitutively secreted by microglia in the retina or brain, and upregulation of IL-27 during neuroinflammation suppresses encephalomyelitis and autoimmune uveitis. However, while IL-35 is structurally and functionally similar to IL-27, the intrinsic roles… read more here.
Keywords: cells constitutively; immune privilege; photoreceptor cells; photoreceptor ... See more keywords
The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.42238
Abstract: The intervertebral disc (IVD) is the largest avascular organ of the body. It is composed of three parts: the nucleus pulposus (NP), the annulus fibrosus (AF) and the cartilaginous endplate (CEP). The central NP is… read more here.
Keywords: ivd; intervertebral disc; immune privilege; degeneration ... See more keywords