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   Articles with "immune profiling" as a keyword



OMIP‐111: Immune‐Profiling of T Helper 1 (Th1), Th2, and Th17 Signatures in Murine Splenocytes by Targeting Intracellular Cytokines

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recommendations! Published in 2025 at "Cytometry Part A"

DOI: 10.1002/cyto.a.24926

Abstract: Functional cytokines shape both innate and adaptive immune responses in the host after infection or immunization. Deep immunophenotyping of the key functional cytokine signatures associated with T cells in murine lymphoid tissue, especially in the… read more here.

Keywords: panel; functional cytokines; murine splenocytes; cell ... See more keywords

Immune profiling of premalignant lesions in patients with Peutz‐Jeghers syndrome

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recommendations! Published in 2024 at "United European Gastroenterology Journal"

DOI: 10.1002/ueg2.12650

Abstract: Abstract Background Peutz‐Jeghers syndrome (PJS), is a rare autosomal dominant hereditary disease characterized by an elevated risk of various cancers. Serine/Threonine Kinase 11 (STK11) gene is a major tumor suppressor crucial for immune evasion with… read more here.

Keywords: jeghers syndrome; pjs polyps; immune profiling; immune evasion ... See more keywords

Immune profiling of melanoma tumors reflecting aggressiveness in a preclinical model

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recommendations! Published in 2017 at "Cancer Immunology, Immunotherapy"

DOI: 10.1007/s00262-017-2056-1

Abstract: Melanoma, like most solid tumors, is highly heterogeneous in terms of invasive, proliferative, and tumor-initiating potential. This heterogeneity is the outcome of differential gene expression resulting from conditions in the tumor microenvironment and the selective… read more here.

Keywords: melanoma; melanoma tumors; profiling melanoma; preclinical model ... See more keywords

Dynamics and correlations in multiplex immune profiling reveal persistent immune inflammation in male drug users after withdrawal.

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recommendations! Published in 2022 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2022.108696

Abstract: Drug withdrawal elicits immune responses that contribute to the development of withdrawal symptoms and relapse. The understanding of the immunologic dynamics after drug withdrawal is limited, precluding the finding of promising immune intervention measures. Here,… read more here.

Keywords: immune profiling; drug; withdrawal; users withdrawal ... See more keywords

Single-cell approaches to immune profiling

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recommendations! Published in 2018 at "Nature"

DOI: 10.1038/d41586-018-05214-w

Abstract: Protein- and sequencing-based technologies are helping researchers to profile immune cells ever more deeply.Protein- and sequencing-based technologies are helping researchers to profile immune cells ever more deeply. read more here.

Keywords: immune profiling; cell approaches; ingle cell; approaches immune ... See more keywords

Deep immune profiling of patients treated with lenalidomide and dexamethasone with or without daratumumab

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recommendations! Published in 2020 at "Leukemia"

DOI: 10.1038/s41375-020-0855-4

Abstract: CD38-targeted antibody, daratumumab, is approved for the treatment of multiple myeloma (MM). Phase 1/2 studies GEN501/SIRIUS revealed a novel immunomodulatory mechanism of action (MOA) of daratumumab that enhanced the immune response, reducing natural killer (NK)… read more here.

Keywords: profiling patients; deep immune; dexamethasone; immune profiling ... See more keywords

Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis

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recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-65561-x

Abstract: Our understanding of the immune response in tuberculosis (TB) remains incomplete. This applies in particular to extrapulmonary TB (EPTB), a highly heterogeneous disease affecting up to 30% of patients in certain regions. Based on data-driven… read more here.

Keywords: extrapulmonary tuberculosis; tuberculosis; profiling delineates; deep immune ... See more keywords

Ex vivo immune profiling in patient blood enables quantification of innate immune effector functions

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recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-91362-5

Abstract: The assessment of a patient’s immune function is critical in many clinical situations. In complex clinical immune dysfunction like sepsis, which results from a loss of immune homeostasis due to microbial infection, a plethora of… read more here.

Keywords: profiling patient; vivo immune; blood; quantification ... See more keywords

Use of Immune Profiling Panel to assess the immune response of septic patients for prediction of worsening as a composite endpoint

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-62202-z

Abstract: Sepsis induces intense, dynamic and heterogeneous host response modulations. Despite improvement of patient management, the risk of mortality and healthcare-associated infections remains high. Treatments to counterbalance immune response are under evaluation, but effective biomarkers are… read more here.

Keywords: composite endpoint; response; worsening composite; immune response ... See more keywords

The evolution of immune profiling: will there be a role for nanoparticles?

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recommendations! Published in 2024 at "Nanoscale horizons"

DOI: 10.1039/d4nh00279b

Abstract: Immune profiling provides insights into the functioning of the immune system, including the distribution, abundance, and activity of immune cells. This understanding is essential for deciphering how the immune system responds to pathogens, vaccines, tumors,… read more here.

Keywords: profiling role; medicine; immune system; immune profiling ... See more keywords

Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up

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recommendations! Published in 2017 at "Annals of Oncology"

DOI: 10.1093/annonc/mdw436

Abstract: Background Lung adenocarcinomas (LUADs) lead to the majority of deaths attributable to lung cancer. We performed whole-exome sequencing (WES) and immune profiling analyses of a unique set of clinically annotated early-stage LUADs to better understand… read more here.

Keywords: exome sequencing; immune profiling; early stage; whole exome ... See more keywords