Immune profiling of melanoma tumors reflecting aggressiveness in a preclinical model
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-017-2056-1
Abstract: Melanoma, like most solid tumors, is highly heterogeneous in terms of invasive, proliferative, and tumor-initiating potential. This heterogeneity is the outcome of differential gene expression resulting from conditions in the tumor microenvironment and the selective… read more here.
Keywords: melanoma; melanoma tumors; profiling melanoma; preclinical model ... See more keywords
Dynamics and correlations in multiplex immune profiling reveal persistent immune inflammation in male drug users after withdrawal.
Sign Up to like & getrecommendations! Published in 2022 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2022.108696
Abstract: Drug withdrawal elicits immune responses that contribute to the development of withdrawal symptoms and relapse. The understanding of the immunologic dynamics after drug withdrawal is limited, precluding the finding of promising immune intervention measures. Here,… read more here.
Keywords: immune profiling; drug; withdrawal; users withdrawal ... See more keywords
Single-cell approaches to immune profiling
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/d41586-018-05214-w
Abstract: Protein- and sequencing-based technologies are helping researchers to profile immune cells ever more deeply.Protein- and sequencing-based technologies are helping researchers to profile immune cells ever more deeply. read more here.
Keywords: immune profiling; cell approaches; ingle cell; approaches immune ... See more keywords
Deep immune profiling of patients treated with lenalidomide and dexamethasone with or without daratumumab
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-0855-4
Abstract: CD38-targeted antibody, daratumumab, is approved for the treatment of multiple myeloma (MM). Phase 1/2 studies GEN501/SIRIUS revealed a novel immunomodulatory mechanism of action (MOA) of daratumumab that enhanced the immune response, reducing natural killer (NK)… read more here.
Keywords: profiling patients; deep immune; dexamethasone; immune profiling ... See more keywords
Ex vivo immune profiling in patient blood enables quantification of innate immune effector functions
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-91362-5
Abstract: The assessment of a patient’s immune function is critical in many clinical situations. In complex clinical immune dysfunction like sepsis, which results from a loss of immune homeostasis due to microbial infection, a plethora of… read more here.
Keywords: profiling patient; vivo immune; blood; quantification ... See more keywords
Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Oncology"
DOI: 10.1093/annonc/mdw436
Abstract: Background Lung adenocarcinomas (LUADs) lead to the majority of deaths attributable to lung cancer. We performed whole-exome sequencing (WES) and immune profiling analyses of a unique set of clinically annotated early-stage LUADs to better understand… read more here.
Keywords: exome sequencing; immune profiling; early stage; whole exome ... See more keywords
Single cell immune profiling in transplantation research
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Transplantation"
DOI: 10.1111/ajt.15316
Abstract: Recently developed single‐cell profiling technologies hold promise to provide new insights including analysis of population heterogeneity and linkage of antigen receptors with gene expression. These technologies produce complex data sets that require knowledge of bioinformatics… read more here.
Keywords: single cell; analysis; transplantation; cell immune ... See more keywords
Organ‐specific immune profiling of Leishmania donovani‐infected hamsters
Sign Up to like & getrecommendations! Published in 2022 at "Parasite Immunology"
DOI: 10.1111/pim.12964
Abstract: Visceral leishmaniasis (VL) is a neglected disease with a broad spectrum of clinical manifestations and involvement of visceral organs. Organ‐specific immune response against the Leishmania donovani (Ld) complex is not yet understood due to the… read more here.
Keywords: specific immune; organ specific; visceral organs; immune profiling ... See more keywords
Immune profiling of COVID-19 patients
Sign Up to like & getrecommendations! Published in 2020 at "Science"
DOI: 10.1126/science.369.6508.1203-l
Abstract: Coronavirus Coronavirus disease 2019 (COVID-19) has affected millions of people globally, yet how the human immune system responds to and influences COVID-19 severity remains unclear. Mathew et al. present a comprehensive atlas of immune modulation… read more here.
Keywords: covid patients; science; disease; covid ... See more keywords
Deep immune profiling uncovers novel associations with clinical phenotypes of multisystem inflammatory syndrome in children (MIS-C)
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-223269
Abstract: Multisystem inflammatory syndrome in children (MISC) is a systemic inflammatory condition seen in children following SARSCoV2 infection or exposure. Symptoms are highly variable and include fever, diarrhoea, cardiogenic shock, respiratory compromise and Kawasaki disease (KD)like… read more here.
Keywords: deep immune; immune profiling; inflammatory syndrome; syndrome children ... See more keywords
Cancer immune profiling unveils biomarkers, immunological pathways, and cell type score associated with glioblastoma patients’ survival
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359221127678
Abstract: Introduction: Glioblastoma (GBM), isocitrate dehydrogenase (IDH) wild-type (IDHwt), and grade 4 astrocytomas, IDH mutant (IDHmut), are the most common and aggressive primary malignant brain tumors in adults. A better understanding of the tumor immune microenvironment… read more here.
Keywords: oncology; immune profiling; cancer immune; idhwt gbm ... See more keywords