Bioinformatics Approaches for Analyzing Multigene Families Encoding Immune Receptors.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1944-5_11
Abstract: Genome sequences are quickly becoming available from a variety of organisms, providing researchers with an abundance of previously inaccessible information and an important source of insight into immune mechanisms. There are a variety of methods… read more here.
Keywords: immune receptors; genome sequences; approaches analyzing; bioinformatics approaches ... See more keywords
Plant immunity: Crosstalk between plant immune receptors
Sign Up to like & getrecommendations! Published in 2021 at "Current Biology"
DOI: 10.1016/j.cub.2021.04.080
Abstract: Plant immunity has long been divided into two 'tiers', involving cell-surface versus intracellular immune receptors. Although both systems can induce similar diagnostic responses, they have been considered independent pathways. Recent work challenges this view, showing… read more here.
Keywords: immunity crosstalk; crosstalk plant; plant; immune receptors ... See more keywords
Innate Immune Receptors as Competitive Determinants of Cell Fate.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2017.05.009
Abstract: Infections can cause a multitude of stresses on the host and microbe. To detect potential infections, the mammalian immune system utilizes several families of pattern recognition receptors, which survey the intracellular and extracellular environments for… read more here.
Keywords: immune receptors; family; cell fate; receptors competitive ... See more keywords
Transfer and engineering of immune receptors to improve recognition capacities in crops.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in plant biology"
DOI: 10.1016/j.pbi.2017.04.010
Abstract: Immune receptors are pivotal elements of the plant immune system that act as sentinels for microbial invasion. Knowingly or unknowingly, breeding for resistance has largely relied on the transfer of immune receptor recognition specificities between… read more here.
Keywords: plant; immune receptors; transfer engineering; engineering immune ... See more keywords
Impact of intracellular innate immune receptors on immunometabolism
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-021-00780-y
Abstract: Immunometabolism, which is the metabolic reprogramming of anaerobic glycolysis, oxidative phosphorylation, and metabolite synthesis upon immune cell activation, has gained importance as a regulator of the homeostasis, activation, proliferation, and differentiation of innate and adaptive… read more here.
Keywords: immune receptors; immune; innate; innate immune ... See more keywords
A cell-free approach to identify binding hotspots in plant immune receptors
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-021-04259-8
Abstract: Plant immune receptors are often difficult to express heterologously, hindering study of direct interactions between these receptors and their targets with traditional biochemical approaches. The cell-free method ribosome display (RD) enables expression of such recalcitrant… read more here.
Keywords: immune receptors; cell free; binding hotspots; plant immune ... See more keywords
Direct recognition of pathogen effectors by plant NLR immune receptors and downstream signalling
Sign Up to like & getrecommendations! Published in 2022 at "Essays in Biochemistry"
DOI: 10.1042/ebc20210072
Abstract: Abstract Plants deploy extracellular and intracellular immune receptors to sense and restrict pathogen attacks. Rapidly evolving pathogen effectors play crucial roles in suppressing plant immunity but are also monitored by intracellular nucleotide-binding, leucine-rich repeat immune… read more here.
Keywords: direct recognition; plant; immune receptors; pathogen effectors ... See more keywords
Effector Identification in Plant Pathogens.
Sign Up to like & getrecommendations! Published in 2023 at "Phytopathology"
DOI: 10.1094/phyto-09-22-0337-kd
Abstract: Effectors play a central role in determining the outcome of plant-pathogen interactions. As key virulence proteins, effectors are collectively indispensable for disease development. By understanding the virulence mechanisms of effectors, fundamental knowledge of microbial pathogenesis… read more here.
Keywords: effector identification; plant; immune receptors; effector ... See more keywords
Enzyme formation by immune receptors
Sign Up to like & getrecommendations! Published in 2020 at "Science"
DOI: 10.1126/science.abf2833
Abstract: Upon pathogen recognition, some plant immune receptors assemble into active enzyme complexes Higher plants have evolved complex immune systems. Intracellular immune receptors known as nucleotide-binding leucine-rich repeat (NLR) proteins are present in both plants and… read more here.
Keywords: immune receptors; formation immune; enzyme formation; recognition ... See more keywords
Bacteroides fragilis outer membrane vesicles preferentially activate innate immune receptors compared to their parent bacteria
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.970725
Abstract: The release of bacterial membrane vesicles (BMVs) has become recognized as a key mechanism used by both pathogenic and commensal bacteria to activate innate immune responses in the host and mediate immunity. Outer membrane vesicles… read more here.
Keywords: cargo; parent bacteria; compared parent; innate immune ... See more keywords
The Emergence of Universal Immune Receptor T Cell Therapy for Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.00176
Abstract: Chimeric antigen receptor (CAR) T cells have shown great success in the treatment of CD19+ hematological malignancies, leading to their recent approval by the FDA as a new cancer treatment modality. However, their broad use… read more here.
Keywords: immune receptors; universal immune; antigen; receptor ... See more keywords