Immune regulator ABIN1 suppresses HIV-1 transcription by negatively regulating the ubiquitination of Tat
Sign Up to like & getrecommendations! Published in 2017 at "Retrovirology"
DOI: 10.1186/s12977-017-0338-5
Abstract: BackgroundA20-binding inhibitor of NF-κB activation (ABIN1), an important immune regulator, was previously shown to be involved in HIV-1 replication. However, the reported studies done with overexpressed ABIN1 provided controversial results.ResultsHere we identified ABIN1 as a… read more here.
Keywords: transcription; hiv transcription; abin1; immune regulator ... See more keywords
Machine learning-based identification of SOX10 as an immune regulator of macrophage in gliomas
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1007461
Abstract: Gliomas, originating from the glial cells, are the most lethal type of primary tumors in the central nervous system. Standard treatments like surgery have not significantly improved the prognosis of glioblastoma patients. Recently, immune therapy… read more here.
Keywords: macrophage gliomas; regulator macrophage; machine learning; immune regulator ... See more keywords
CD96 as a Potential Immune Regulator in Cancers
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021303
Abstract: The discovery of CTLA-4 and PD-1 checkpoints has prompted scientific researchers and the pharmaceutical industry to develop and conduct extensive research on tumor-specific inhibitors. As a result, the list of potential immune checkpoint molecules is… read more here.
Keywords: cd96 potential; potential immune; immune; immune regulator ... See more keywords