Human splenic polymorphonuclear myeloid‐derived suppressor cells (PMN‐MDSC) are strategically located immune regulatory cells in cancer
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Immunology"
DOI: 10.1002/eji.202048666
Abstract: In contrast to the mouse, functional assets of polymorphonuclear myeloid‐derived suppressor cells (PMN‐MDSC) in the human spleen remain to be better elucidated. Here, we report that the spleen in gastric and pancreatic cancer adopts an… read more here.
Keywords: pmn mdsc; immune regulatory; polymorphonuclear myeloid; cancer ... See more keywords
The role of immune regulatory molecules in rheumatoid arthritis: Implication for etiopathogenesis and prospective for treatment
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30855
Abstract: Rheumatoid arthritis (RA) is considered an autoimmune chronic disorder and the most common inflammatory arthropathy. Disease progression in RA begins with asymptomatic autoimmune responses in cases with a genetic or environmental predisposition, that alters to… read more here.
Keywords: role immune; cell; immune regulatory; rheumatoid arthritis ... See more keywords
Human bone marrow adipocytes display distinct immune regulatory properties
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.07.023
Abstract: Background The bone marrow (BM) is a major reservoir of resting memory T cells and long-lived plasma cells, capable of providing protection against recurrent infections. Whether the age-related accumulation of adipose tissue in the BM… read more here.
Keywords: immune regulatory; fmat adipocytes; adipose tissue; marrow ... See more keywords
Role of Innate Immune Regulatory Genes, FOXP3 and FOS in Chronic Hepatitis B Infection.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2021.0145
Abstract: Persistence of hepatitis B virus (HBV) infection leading to chronic infection and its sequalae is responsible for over half a million deaths worldwide. The reason for persistence of chronic hepatitis B (CHB) infection is still… read more here.
Keywords: chb; immune regulatory; infection; chronic hepatitis ... See more keywords
The Role of Immune Regulatory Molecules in COVID-19.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2021.0211
Abstract: As the fifth pandemic in the 21st century, coronavirus 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become the most prominent global concern in the last 2 years. Variable manifestations characterize… read more here.
Keywords: role immune; role; immune regulatory; infection ... See more keywords
ImmuneRegulation: a web-based tool for identifying human immune regulatory elements
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz450
Abstract: Abstract Humans vary considerably both in their baseline and activated immune phenotypes. We developed a user-friendly open-access web portal, ImmuneRegulation, that enables users to interactively explore immune regulatory elements that drive cell-type or cohort-specific gene… read more here.
Keywords: immune regulatory; immuneregulation; gene expression; gene ... See more keywords
Immune regulatory cytokines in seminal plasma of healthy men: A scoping review and analysis of variance.
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DOI: 10.1111/andr.13424
Abstract: OBJECTIVE Seminal plasma cytokines are associated with fertility and reproductive health, but progressing their clinical utility is hampered by absence of reference data on concentration ranges of relevant cytokines in healthy men. We employed a… read more here.
Keywords: immune regulatory; healthy men; plasma; regulatory cytokines ... See more keywords
Immune regulatory and anti‐resorptive activities of tanshinone IIA sulfonate attenuates rheumatoid arthritis in mice
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DOI: 10.1111/bph.17312
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and painful joint destruction. Current treatments are helpful in RA remission, but strong immunosuppressive activity and patient resistance are clinical issues. This study explores… read more here.
Keywords: anti resorptive; regulatory anti; resorptive activities; immune regulatory ... See more keywords
Characterization of the immune regulatory property of CD22+ CD9+ B cells
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13539
Abstract: Immunodisruptive homeostasis is recognized in allergic disorders. The mechanism of restoration of immunologic homeostasis in the body is not fully understood. Galectin‐9 (Gal9) and CD22 have immune regulatory functions. The goal of this study is… read more here.
Keywords: cd22; b10 cells; cd22 cd9; immune regulatory ... See more keywords
The Immune Regulatory Functions in B Cells Are Restored by CpG to Reduce Experimental Food Allergy
Sign Up to like & getrecommendations! Published in 2024 at "Immunology"
DOI: 10.1111/imm.13868
Abstract: Dysfunctional immune regulation contributes to the pathogenesis of food allergy (FA). The mechanism behind regulatory B‐cell dysfunction is unclear. CpG has immune regulatory functions. The purpose of this study is to use CpG to recover… read more here.
Keywords: food allergy; functions cells; restored cpg; immune regulatory ... See more keywords
Abstract 907: Identification of a stem cell-specific secretory immune regulatory ligand
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DOI: 10.1158/1538-7445.am2025-907
Abstract: Immunotherapies have transformed cancer treatment, but subsets of patients experience differential responses. Patients with squamous cell carcinomas (SCCs) in various tissues exhibit a high rate of relapse after their initial response to immunotherapies. Recent research… read more here.
Keywords: stem cell; ctla2a; immune regulatory; cell ... See more keywords