Intrahepatic T‐Cell Receptor β Immune Repertoire Is Essential for Liver Regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30067
Abstract: T lymphocytes synergize with the cellular immune system to promote hepatocyte regeneration. The T‐cell receptor (TCR) immune repertoire is closely associated with the host immune response and regenerative proliferation. High‐throughput sequencing of TCR provides deep… read more here.
Keywords: immune repertoire; liver regeneration; regeneration; cell receptor ... See more keywords
High-throughput sequencing of the immune repertoire in oncology: Applications for clinical diagnosis, monitoring, and immunotherapies.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.12.017
Abstract: The diagnostic, monitoring and therapeutic options for cancers currently remain limited. These limitations represent a large threat to human health. Adaptive immunity, which is dependent on diverse repertoires of B cell receptors (BCRs) and T… read more here.
Keywords: cell; immune repertoire; oncology; sequencing immune ... See more keywords
Moringa oleifera polysaccharide regulates colonic microbiota and immune repertoire in C57BL/6 mice.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.12.085
Abstract: This study investigated the effects of Moringa oleifera polysaccharide (MOP) on serum immune indices, immune organ indices, colonic microflora and immune repertoire of mice. Forty male SPF C57BL/6 mice were randomly divided into four groups… read more here.
Keywords: moringa oleifera; immune repertoire; mice; c57bl mice ... See more keywords
High-throughput immune repertoire analysis with IGoR
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-02832-w
Abstract: High-throughput immune repertoire sequencing is promising to lead to new statistical diagnostic tools for medicine and biology. Successful implementations of these methods require a correct characterization, analysis, and interpretation of these data sets. We present… read more here.
Keywords: igor; throughput immune; immune repertoire; high throughput ... See more keywords
Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09930-3
Abstract: Studying immune repertoire in the context of organ transplant provides important information on how adaptive immunity may contribute and modulate graft rejection. Here we characterize the peripheral blood immune repertoire of individuals before and after… read more here.
Keywords: immune repertoire; rejection; transplant; cell ... See more keywords
PIRD: Pan immune repertoire database.
Sign Up to like & getrecommendations! Published in 2019 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz614
Abstract: MOTIVATION T and B cell receptors (TCRs and BCRs) play a pivotal role in the adaptive immune system by recognizing an enormous variety of external and internal antigens. Understanding these receptors is critical for exploring… read more here.
Keywords: pird; immune repertoire; pan immune; database ... See more keywords
B Cell Immune Repertoire Sequencing Identifies Pre-transplant Rejection Risk
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation"
DOI: 10.1097/01.tp.0000542591.08680.f3
Abstract: Background The diversity of the B cell immune repertoire may drive humoral injury and rejection in organ transplantation (tx). Methods We utilized advances in next-generation sequencing of B cells and custom computational pipelines to study… read more here.
Keywords: immune repertoire; diversity; rejection; repertoire ... See more keywords
Post-hospitalization rehabilitation alleviates long-term immune repertoire alteration in COVID-19 convalescent patients.
Sign Up to like & getrecommendations! Published in 2023 at "Cell proliferation"
DOI: 10.1111/cpr.13450
Abstract: The global pandemic of Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an once-in-a-lifetime public health crisis. Among hundreds of millions of people who have contracted with or are… read more here.
Keywords: convalescent patients; immune repertoire; hospitalization rehabilitation; repertoire ... See more keywords
Immune repertoire profiling for disease pathobiology
Sign Up to like & getrecommendations! Published in 2022 at "Pathology International"
DOI: 10.1111/pin.13284
Abstract: Lymphocytes consist of highly heterogeneous populations, each expressing a specific cell surface receptor corresponding to a particular antigen. Lymphocytes are both the cause and regulator of various diseases, including autoimmune/allergic diseases, lifestyle diseases, neurodegenerative diseases,… read more here.
Keywords: immune repertoire; repertoire sequencing; pathology; repertoire ... See more keywords
Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm0220
Abstract: Conventional approaches to isolate and characterize nanobodies are laborious. We combine phage display, multivariate enrichment, next-generation sequencing, and a streamlined screening strategy to identify numerous anti–severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nanobodies. We characterize… read more here.
Keywords: immune repertoire; multivariate mining; alpaca immune; mining alpaca ... See more keywords
PO-394 Performance of a targeted T cell receptor beta immune repertoire sequencing panel in several FFPE tissue types – a tool for interrogation of the tumour microenvironment
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.906
Abstract: Introduction T cell receptor beta (TCRβ) immune repertoire analysis by next-generation sequencing is a valuable tool for research studies of the tumour microenvironment and potential immune responses to cancer immunotherapy. Here we describe a TCRβ… read more here.
Keywords: immune repertoire; input; tissue; repertoire sequencing ... See more keywords