High versus low dose irradiation for tumor immune reprogramming.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2020.08.001
Abstract: Local administration of ionizing radiation to tumors can promote anticancer immune responses that lead to the abscopal regression of distant metastases, especially in patients receiving systemic immune-checkpoint inhibitors. Growing preclinical evidence indicates that high-dose irradiation… read more here.
Keywords: irradiation; low dose; immune reprogramming; tumor immune ... See more keywords
Dedifferentiation of Epithelial Cells Incorporates Immune Reprogramming.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2021.01.007
Abstract: Recent innovations in immunotherapies have cured cancers but remain ineffective in pancreatic cancer, which exhibits intertwined dynamics of dedifferentiation of epithelium and reprogramming ofimmunosuppression. Emerging evidence reveals the biological mechanisms through which dedifferentiation recapitulates immune… read more here.
Keywords: epithelial cells; immune reprogramming; cells incorporates; incorporates immune ... See more keywords
Tumor-Homing and Immune-Reprogramming Cellular Nanovesicles for Photoacoustic Imaging-Guided Phototriggered Precise Chemoimmunotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c04983
Abstract: Many studies have focused on developing effective therapeutic strategies to selectively destroy primary tumors, eliminate metastatic lesions, and prevent tumor recurrence with minimal side effects on normal tissues. In this work, we synthesized engineered cellular… read more here.
Keywords: tumor homing; homing immune; cellular nanovesicles; immune reprogramming ... See more keywords