Cyclic stretch regulates immune responses via tank‐binding kinase 1 expression in macrophages
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13526
Abstract: Macrophages distributed in tissues throughout the body contribute to homeostasis. In the inflammatory state, macrophages undergo mechanical stress that regulates the signal transduction of immune responses and various cellular functions. However, the effects of the… read more here.
Keywords: stretch; immune responses; cyclic stretch; tank binding ... See more keywords
Hyperacute immune responses associate with immediate neuropathology and motor dysfunction in large vessel occlusions
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51719
Abstract: Despite successful endovascular therapy, a proportion of stroke patients exhibit long‐term functional decline, regardless of the cortical reperfusion. Our objective was to evaluate the early activation of the adaptive immune response and its impact on… read more here.
Keywords: large vessel; immediate neuropathology; responses associate; immune responses ... See more keywords
Engineered Ferritin Nanoparticle Vaccines Enable Rapid Screening of Antibody Functionalisation to Boost Immune Responses.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202202595
Abstract: Employing monoclonal antibodies to target vaccine antigens to different immune cells within lymph nodes where adaptive immunity is initiated can provide a mechanism to fine tune the magnitude of quality of immune responses. However, studying… read more here.
Keywords: engineered ferritin; ferritin nanoparticle; immune responses; rapid screening ... See more keywords
Toward a Better Regeneration through Implant‐Mediated Immunomodulation: Harnessing the Immune Responses
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DOI: 10.1002/advs.202100446
Abstract: Abstract Tissue repair/regeneration, after implantation or injury, involves comprehensive physiological processes wherein immune responses play a crucial role to enable tissue restoration, amidst the immune cells early‐stage response to tissue damages. These cells break down… read more here.
Keywords: immunomodulation; immune responses; regeneration; tissue ... See more keywords
Rational Nanomedicine Design Enhances Clinically Physical Treatment‐Inspired or Combined Immunotherapy
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DOI: 10.1002/advs.202203921
Abstract: Independent of tumor type and non‐invasive or minimally‐invasive feature, current physical treatments including ultrasound therapy, microwave ablation (MWA), and radiofrequency ablation (RFA) are widely used as the local treatment methods in clinics for directly killing… read more here.
Keywords: physical treatment; rational nanomedicine; immunotherapy; immune responses ... See more keywords
Antiviral Nanobiologic Therapy Remodulates Innate Immune Responses to Highly Pathogenic Coronavirus.
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DOI: 10.1002/advs.202207249
Abstract: Highly pathogenic coronavirus (CoV) infection induces a defective innate antiviral immune response coupled with the dysregulated release of proinflammatory cytokines and finally results in acute respiratory distress syndrome (ARDS). A timely and appropriate triggering of… read more here.
Keywords: immune responses; pathogenic coronavirus; antiviral nanobiologic; innate immune ... See more keywords
Eicosanoid mediation of immune responses at early bacterial infection stage and its inhibition by Photorhabdus temperata subsp. temperata, an entomopathogenic bacterium.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21502
Abstract: An entomopathogenic bacterium Photorhabdus temperata subsp. temperata (Ptt) infects insect hemocoel by the vectoring activity of its symbiotic nematode, Heterorhabditis megidis. The bacterium induces host immunosuppression by inhibiting eicosanoid biosynthesis. This study investigated the role… read more here.
Keywords: bacterium; infection stage; immune responses; infection ... See more keywords
Changes in immune responses of Helicoverpa armigera Hübner followed by feeding on Knotgrass, Polygonum persicaria agglutinin.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21543
Abstract: There is no study implying the effect of plant lectins on insect immune elements in both challenged and non-challenged conditions with entomopathogenic agents. Lectins may bind to immune receptors on the surface of insect hemocytes,… read more here.
Keywords: helicoverpa armigera; polygonum persicaria; control; immune responses ... See more keywords
Persistent human bocavirus 1 infection and tonsillar immune responses
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DOI: 10.1002/clt2.12030
Abstract: Abstract Background Persistent human bocavirus 1 (HBoV1) infection is a common finding in patients suffering from chronic tonsillar disease. However, the associations between HBoV1 infection and specific immune reactions are not completely known. We aimed… read more here.
Keywords: serology; infection; immune responses; hbov1 infection ... See more keywords
Crossroads between immune responses and physiological regulation: Metabolic control of resistance versus tolerance against disease
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DOI: 10.1002/eji.201948159
Abstract: If a threat cannot be avoided, the organism has two defense options: it can try to eliminate the threatening agent or boost physiological mechanisms to tolerate the challenge and its consequences. Both strategies can be… read more here.
Keywords: tolerance; control; immune responses; disease ... See more keywords
Tumor cell‐intrinsic RIG‐I signaling governs synergistic effects of immunogenic cancer therapies and checkpoint inhibitors in mice
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202049158
Abstract: Novel immunotherapeutic concepts, including immune checkpoint inhibitors of PD-1 and CTLA-4, have dramatically changed clinical practice in cancer treatment. These therapies (re)invigorate T-cell-based tumor immune responses. However, for many patients these therapies fail, as the… read more here.
Keywords: checkpoint inhibitors; immune responses; tumor cell; cancer ... See more keywords