Downregulation of Three Immune-Specific Core Genes and the Regulatory Pathways in Children and Adult Friedreich's Ataxia: A Comprehensive Analysis Based on Microarray
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DOI: 10.3389/fneur.2021.816393
Abstract: Background Friedreich's ataxia (FRDA) is a familial hereditary disorder that lacks available therapy. Therefore, the identification of novel biomarkers and key mechanisms related to FRDA progression is urgently required. Methods We identified the up-regulated and… read more here.
Keywords: child adult; adult frda; immune specific; analysis ... See more keywords
The Prognostic and Predictive Role of Xeroderma Pigmentosum Gene Expression in Melanoma
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DOI: 10.3389/fonc.2022.810058
Abstract: Background Assessment of immune-specific markers is a well-established approach for predicting the response to immune checkpoint inhibitors (ICIs). Promising candidates as ICI predictive biomarkers are the DNA damage response pathway genes. One of those pathways,… read more here.
Keywords: gene; xeroderma pigmentosum; immune specific; expression ... See more keywords