AMBRA1 controls the translation of immune-specific genes in T lymphocytes
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2416722121
Abstract: Significance Understanding the molecular control of protein expression after TCR stimulation, including the role of translation, is crucial for developing immunological treatments for autoimmune diseases and cancers. In this study, we identified an unexpected role… read more here.
Keywords: immune specific; translation; controls translation; ambra1 controls ... See more keywords
Downregulation of Three Immune-Specific Core Genes and the Regulatory Pathways in Children and Adult Friedreich's Ataxia: A Comprehensive Analysis Based on Microarray
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2021.816393
Abstract: Background Friedreich's ataxia (FRDA) is a familial hereditary disorder that lacks available therapy. Therefore, the identification of novel biomarkers and key mechanisms related to FRDA progression is urgently required. Methods We identified the up-regulated and… read more here.
Keywords: child adult; adult frda; immune specific; analysis ... See more keywords
The Prognostic and Predictive Role of Xeroderma Pigmentosum Gene Expression in Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.810058
Abstract: Background Assessment of immune-specific markers is a well-established approach for predicting the response to immune checkpoint inhibitors (ICIs). Promising candidates as ICI predictive biomarkers are the DNA damage response pathway genes. One of those pathways,… read more here.
Keywords: gene; xeroderma pigmentosum; immune specific; expression ... See more keywords