Immune stimulation during chemotherapy increases incidence of acute graft versus host disease in acute myeloid leukemia: A study on behalf of SFGM-TC and ALFA.
Sign Up to like & getrecommendations! Published in 2017 at "Leukemia research"
DOI: 10.1016/j.leukres.2017.01.002
Abstract: 60-70% of AML patients have an indication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) during their treatment. Graft versus host disease (GvHD), the major cause of mortality and comorbidities post-transplantation, develops by immunological mechanism and… read more here.
Keywords: incidence; versus host; graft versus; immune stimulation ... See more keywords
Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-1098
Abstract: Systemic immune stimulation has been associated with increased risk of myeloid malignancies, but the pathogenic link is unknown. We demonstrate in animal models that experimental systemic immune activation alters the bone marrow stromal microenvironment, disarranging… read more here.
Keywords: persistent immune; exacerbates genetically; stimulation; stimulation exacerbates ... See more keywords
Metabolomic and transcriptomic profiles after immune stimulation in the zebrafish testes.
Sign Up to like & getrecommendations! Published in 2023 at "Genomics"
DOI: 10.2139/ssrn.4247250
Abstract: Fish farms are prone to disease outbreaks and stress due to high-density rearing conditions in tanks and sea cages, adversely affecting growth, reproduction, and metabolism. To understand the molecular mechanisms affected in the gonads of… read more here.
Keywords: profiles immune; immune stimulation; metabolomic transcriptomic; transcriptomic profiles ... See more keywords
Exposure to Antibiotics Affects Saponin Immersion-Induced Immune Stimulation and Shift in Microbial Composition in Zebrafish Larvae
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.02588
Abstract: In the last decades, pollution of the environment by large scale use of antibiotics in agriculture and human medicine have led to increased antimicrobial resistance in both the environment and the host animal microbiome. Disturbances… read more here.
Keywords: zebrafish larvae; exposure; induced immune; larvae ... See more keywords
The Poly I:C maternal immune stimulation model shows unique patterns of brain metabolism, morphometry, and plasticity in female rats
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.1022622
Abstract: Introduction: Prenatal infections are associated with an increased risk of the onset of schizophrenia. Rodent models of maternal immune stimulation (MIS) have been extensively used in preclinical studies. However, many of these studies only include… read more here.
Keywords: metabolism; female rats; brain; maternal immune ... See more keywords
Innate Immune Stimulation Should not be Overlooked in Post-exposure Prophylaxis and Early Therapy for Coronavirus Infections.
Sign Up to like & getrecommendations! Published in 2022 at "MEDICC review"
DOI: 10.37757/mr2022.v24.n1.5
Abstract: We discuss the suitability of innate immune stimulation in acute respiratory infection post-exposure prophylaxis. The induction of innate immunity can be used to reduce susceptibility to immune-evasive pathogens (coronavirus, influenza virus, respiratory syncytial virus and… read more here.
Keywords: immune stimulation; exposure prophylaxis; post exposure; innate immune ... See more keywords