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Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113401
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE According to the theory of traditional Chinese medicine, the main pathogenesis of severe hand, foot and mouth disease (HFMD) is that the heat and wet poisons are deeply trapped in the viscera, which…
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Keywords:
rb1 immune;
antiviral activity;
ginsenoside rb1;
immune stimulatory ... See more keywords
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Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b06141
Abstract: The cyclic dinucleotides (CDNs) c-di-GMP, c-di-AMP, and c-AMP-GMP are widely utilized as second messengers in bacteria, where they signal lifestyle changes such as motility and biofilm formation, cell wall and membrane homeostasis, virulence, and exo-electrogenesis.…
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Keywords:
cyclic dinucleotides;
immune stimulatory;
synthesis possible;
possible canonical ... See more keywords
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Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-01145-4
Abstract: Background The balance between immune-stimulatory and immune-suppressive mechanisms in the tumour microenvironment is associated with tumour rejection and can predict the efficacy of immune checkpoint-inhibition therapies. Methods We consider the observed differences between the transcriptional…
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Keywords:
immune stimulatory;
miracle;
cancer;
balance ... See more keywords
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Published in 2020 at "mAbs"
DOI: 10.1080/19420862.2020.1764829
Abstract: ABSTRACT Biologics have the potential to induce an immune response when used therapeutically. A number of in vitro assays are currently used preclinically to predict the risk of immunogenicity, but the validation of these preclinical…
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Keywords:
post hoc;
distinct immune;
immunogenicity;
immune stimulatory ... See more keywords