Ginsenoside Rb1 is an immune-stimulatory agent with antiviral activity against enterovirus 71.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113401
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE According to the theory of traditional Chinese medicine, the main pathogenesis of severe hand, foot and mouth disease (HFMD) is that the heat and wet poisons are deeply trapped in the viscera, which… read more here.
Keywords: rb1 immune; antiviral activity; ginsenoside rb1; immune stimulatory ... See more keywords
Synthesis of All Possible Canonical (3'-5'-Linked) Cyclic Dinucleotides and Evaluation of Riboswitch Interactions and Immune-Stimulatory Effects.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b06141
Abstract: The cyclic dinucleotides (CDNs) c-di-GMP, c-di-AMP, and c-AMP-GMP are widely utilized as second messengers in bacteria, where they signal lifestyle changes such as motility and biofilm formation, cell wall and membrane homeostasis, virulence, and exo-electrogenesis.… read more here.
Keywords: cyclic dinucleotides; immune stimulatory; synthesis possible; possible canonical ... See more keywords
A balance score between immune stimulatory and suppressive microenvironments identifies mediators of tumour immunity and predicts pan-cancer survival
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DOI: 10.1038/s41416-020-01145-4
Abstract: Background The balance between immune-stimulatory and immune-suppressive mechanisms in the tumour microenvironment is associated with tumour rejection and can predict the efficacy of immune checkpoint-inhibition therapies. Methods We consider the observed differences between the transcriptional… read more here.
Keywords: immune stimulatory; miracle; cancer; balance ... See more keywords
Post-hoc assessment of the immunogenicity of three antibodies reveals distinct immune stimulatory mechanisms
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DOI: 10.1080/19420862.2020.1764829
Abstract: ABSTRACT Biologics have the potential to induce an immune response when used therapeutically. A number of in vitro assays are currently used preclinically to predict the risk of immunogenicity, but the validation of these preclinical… read more here.
Keywords: post hoc; distinct immune; immunogenicity; immune stimulatory ... See more keywords