Imaging phenotypes from MRI for the prediction of glioma immune subtypes from RNA sequencing: A multicenter study
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13380
Abstract: Tumor subtyping based on its immune landscape may guide precision immunotherapy. The aims of this study were to identify immune subtypes of adult diffuse gliomas with RNA sequencing data, and to noninvasively predict this subtype… read more here.
Keywords: rna sequencing; immune subtypes; radiomic signature; subtype ... See more keywords
Identification of tumor antigens and immune subtypes of glioma for mRNA vaccine development
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DOI: 10.1002/cam4.4633
Abstract: Recent evidence suggested that the mRNA vaccine has been effective for many tumors, but its progress in gliomas was slow. In this study, we screened potential tumor antigens and suitable populations for mRNA vaccine to… read more here.
Keywords: mrna vaccine; immune subtypes; tumor antigens; vaccine ... See more keywords
Personalized immune subtypes based on machine learning predict response to checkpoint blockade in gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac554
Abstract: Immune checkpoint inhibitors (ICI) show high efficiency in a small fraction of advanced gastric cancer (GC). However, personalized immune subtypes have not been developed for the prediction of ICI efficiency in GC. Herein, we identified… read more here.
Keywords: personalized immune; immune subtypes; checkpoint; gastric cancer ... See more keywords
Prognostic significance of immune landscape in tumour microenvironment of endometrial cancer
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DOI: 10.1111/jcmm.15408
Abstract: Tumour microenvironment (TME) is crucial to tumorigenesis. This study aimed to uncover the differences in immune phenotypes of TME in endometrial cancer (EC) using Uterine Corpus Endometrial Carcinoma (UCEC) cohort and explore the prognostic significance.… read more here.
Keywords: endometrial cancer; immune subtypes; cancer; tumour microenvironment ... See more keywords
Identification of tumour antigens and immune subtypes in the development of an anti‐cancer vaccine for endometrial carcinoma
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DOI: 10.1111/sji.13250
Abstract: Therapeutic application of vaccines to endometrial carcinoma (EC) remains uncertain. In this study, we aimed to identify potential tumour antigens for use in the development of an anti‐tumour mRNA vaccine and clarify immune subtypes and… read more here.
Keywords: tumour antigens; endometrial carcinoma; immune subtypes; tumour ... See more keywords
Analysis of the Heterogeneity of the Tumor Microenvironment and the Prognosis and Immunotherapy Response of Different Immune Subtypes in Hepatocellular Carcinoma
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DOI: 10.1155/2022/1087399
Abstract: Purpose The current clinical classification of hepatocellular carcinoma (HCC) cannot well predict the patient's possible response to the treatment plan, nor can it predict the patient's prognosis. We use the gene expression patterns of patients… read more here.
Keywords: hepatocellular carcinoma; prognosis; immune subtypes; different immune ... See more keywords
Defining Diffuse Large B-Cell Lymphoma Immunotypes by CD8+ T Cells and Natural Killer Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/3168172
Abstract: Background There is a poor prognosis for diffuse large B-cell lymphoma (DLBCL), one of the most common types of non-Hodgkin lymphoma (NHL). Through gene expression profiles, this study intends to reveal potential subtypes among patients… read more here.
Keywords: lymphoma; cell lymphoma; immune subtypes; large cell ... See more keywords
Identification of tumor antigens and immune subtypes of pancreatic adenocarcinoma for mRNA vaccine development
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DOI: 10.1186/s12943-021-01310-0
Abstract: Background Although mRNA vaccines have been effective against multiple cancers, their efficacy against pancreatic adenocarcinoma (PAAD) remains undefined. Accumulating evidence suggests that immunotyping can indicate the comprehensive immune status in tumors and their immune microenvironment,… read more here.
Keywords: mrna vaccine; pancreatic adenocarcinoma; immune subtypes; vaccine development ... See more keywords
Identification of tumor antigens and immune subtypes in lower grade gliomas for mRNA vaccine development
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DOI: 10.1186/s12967-021-03014-x
Abstract: Background As an important part of tumor immunotherapy for adjunct, therapeutic tumor vaccines have been effective against multiple solid cancers, while their efficacy against lower grade glioma (LGG) remains undefined. Immunophenotyping of tumors is an… read more here.
Keywords: tumor antigens; potential antigens; immune subtypes; lower grade ... See more keywords
A novel immune subtype classification of ER-positive, PR-negative and HER2-negative breast cancer based on the genomic and transcriptomic landscape
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-021-03076-x
Abstract: Background The diversity and plasticity behind ER+/PR−/HER2− breast cancer have not been widely explored. It is essential to identify heterogeneous microenvironment phenotypes and investigate specific genomic events driving the formation of these phenotypes. Methods Based… read more here.
Keywords: breast; breast cancer; immune subtypes; her2 ... See more keywords
Identification of immune subtypes and their prognosis and molecular implications in colorectal cancer
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DOI: 10.1371/journal.pone.0278114
Abstract: Immune composition is commonly heterogeneous and varies among colorectal cancer (CRC) patients. A comprehensive immune classification may act as important characteristics to predict CRC prognosis. Thus, we aimed to identify novel immune specific subtypes to… read more here.
Keywords: across immune; prognosis; immune subtypes; colorectal cancer ... See more keywords