Human cancer evolution in the context of a human immune system in mice
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12374
Abstract: Immunotherapy is one of the most promising cancer treatment modalities, but the lack of appropriate preclinical in vivo models hampers the development of novel immunotherapeutic strategies. Here, we studied the ability of transplanted human cancer… read more here.
Keywords: human cancer; system mice; immune system; cancer ... See more keywords
The immune system in multiple myeloma and precursor states: Lessons and implications for immunotherapy and interception
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26752
Abstract: Multiple myeloma (MM) and its precursor monoclonal gammopathy of undetermined significance (MGUS) are distinct disorders that likely originate in the setting of chronic immune activation. Evolution of these lesions is impacted by cross‐talk with both… read more here.
Keywords: myeloma precursor; multiple myeloma; immune system;
Effects of C‐section on the human microbiota
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Human Biology"
DOI: 10.1002/ajhb.23196
Abstract: Humans and other animals have coevolved with microbes that colonize the epithelia that covers the body’s surfaces, both outside (the skin) and inside (the invaginations and gut). As such, the composite of a vertebrate’s cells… read more here.
Keywords: microbiota; effects section; immune system; section human ... See more keywords
How microplastic components influence the immune system and impact on children health: Focus on cancer
Sign Up to like & getrecommendations! Published in 2020 at "Birth Defects Research"
DOI: 10.1002/bdr2.1779
Abstract: As a result of human socioeconomic activity, industrial wastes have increased distressingly. Plastic pollution is globally distributed across the world due to its properties of buoyancy and durability. A big health hazard is the sorption… read more here.
Keywords: influence immune; immune system; health; microplastic components ... See more keywords
Associations between the human immune system and gut microbiome with neurodevelopment in the first 5 years of life: A systematic scoping review.
Sign Up to like & getrecommendations! Published in 2023 at "Developmental psychobiology"
DOI: 10.1002/dev.22360
Abstract: The aim of this review was to map the literature assessing associations between maternal or infant immune or gut microbiome biomarkers and child neurodevelopmental outcomes within the first 5 years of life. We conducted a PRISMA-ScR… read more here.
Keywords: review; immune system; system gut; gut microbiome ... See more keywords
Social dilemma in the external immune system of the red flour beetle? It is a matter of time
Sign Up to like & getrecommendations! Published in 2017 at "Ecology and Evolution"
DOI: 10.1002/ece3.3198
Abstract: Abstract Sociobiology has revolutionized our understanding of interactions between organisms. Interactions may present a social dilemma where the interests of individual actors do not align with those of the group as a whole. Viewed through… read more here.
Keywords: social dilemma; secretion; system red; external immune ... See more keywords
The function of the immune system according to The Other Side of Bob Dylan
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201770075
Abstract: In the course Functional Anatomy, a bachelor course which I teach at University College Roosevelt, I have tried to introduce each organ system with an appropriate fragment of a Bob Dylan song. In preparation of… read more here.
Keywords: immune system; system; bob dylan;
The bidirectional interaction of the gut microbiome and the innate immune system: Implications for chemotherapy‐induced gastrointestinal toxicity
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.31836
Abstract: Chemotherapy‐induced gastrointestinal toxicity (CIGT) occurs in up to 80% of all patients undergoing cancer treatment, and leads to symptoms such as diarrhoea, abdominal bleeding and pain. There is currently limited understanding of how to predict… read more here.
Keywords: gastrointestinal toxicity; toxicity; immune system; gut microbiome ... See more keywords
A decoy strategy to activate the immune system
Sign Up to like & getrecommendations! Published in 2021 at "IUBMB Life"
DOI: 10.1002/iub.2548
Abstract: An approach comprising a novel fusion protein and inactivated virus, as a more efficacious vaccine against invading viruses is presented, using SARS‐CoV‐2 as a most prominent example. The fusion protein consists of the Hepatitis B… read more here.
Keywords: fusion protein; immune system; would bind;
Modulating inflammation through the negative regulation of NF‐κB signaling
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3mir0817-346rrr
Abstract: Immune system activation is essential to thwart the invasion of pathogens and respond appropriately to tissue damage. However, uncontrolled inflammation can result in extensive collateral damage underlying a diverse range of auto‐inflammatory, hyper‐inflammatory, and neoplastic… read more here.
Keywords: modulating inflammation; inflammation; regulation signaling; immune system ... See more keywords
Embracing microbial exposure in mouse research
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4ri0718-273r
Abstract: Research using mouse models have contributed essential knowledge toward our current understanding of how the human immune system functions. One key difference between humans and typical laboratory mice, however, is exposure to pathogens in their… read more here.
Keywords: research; mouse; immune system; mouse models ... See more keywords