Abstract PR16: Specific activation of the G protein-coupled estrogen receptor inhibits melanoma and other cancers and potentiates immune and targeted therapies
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.mel2019-pr16
Abstract: Modern immune and targeted therapies appear more effective against advanced melanoma in women than in men. Melanoma incidence is also lower in women. Similar sex differences are observed in other tumors that are not classically… read more here.
Keywords: activation; protein coupled; melanoma; targeted therapies ... See more keywords
Immunomodulation by the Commensal Microbiome During Immune-Targeted Interventions: Focus on Cancer Immune Checkpoint Inhibitor Therapy and Vaccination
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DOI: 10.3389/fimmu.2021.643255
Abstract: Emerging evidence in clinical and preclinical studies indicates that success of immunotherapies can be impacted by the state of the microbiome. Understanding the role of the microbiome during immune-targeted interventions could help us understand heterogeneity… read more here.
Keywords: immune; interventions focus; microbiome immune; immunomodulation ... See more keywords
Epigenetic Mechanisms Underlying Melanoma Resistance to Immune and Targeted Therapies
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DOI: 10.3390/cancers14235858
Abstract: Simple Summary Despite major recent therapeutic advances, melanoma remains the deadliest form of skin cancer due to the capacity of melanoma cells to adapt to drug treatment and become resistant. Improved understanding of melanoma suggests… read more here.
Keywords: targeted therapies; melanoma; resistance; immune targeted ... See more keywords
Molecular Immune Targeted Imaging of Tumor Microenvironment
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DOI: 10.7150/ntno.66556
Abstract: Novel targeted therapies are rapidly emerging for the treatment of cancer. With the advent of new immune targeting agents, understanding the changes in the tumor microenvironment (TME) is critical. Given the complexity and several cellular… read more here.
Keywords: imaging tumor; tme; targeted imaging; molecular immune ... See more keywords