Novel Murine Model of Immune Thrombocytopaenia through Immunized CD41 Knockout Mice.
Sign Up to like & getrecommendations! Published in 2019 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0038-1677032
Abstract: Immune thrombocytopaenia (ITP) is the most common autoimmune bleeding disorder, where platelets are destroyed by auto-antibodies and/or cell-mediated mechanisms. To understand the pathogenesis of ITP and explore novel therapeutics, three types of animal models have… read more here.
Keywords: immune thrombocytopaenia; model; mice; cd41 ... See more keywords
Platelet and immune characteristics of immune thrombocytopaenia patients non‐responsive to therapy reveal severe immune dysregulation
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Haematology"
DOI: 10.1111/bjh.16459
Abstract: Multifactorial mechanisms leading to diminished platelet counts in immune thrombocytopaenia (ITP) might condition the ability of patients with ITP to respond to treatments. Examining their platelet and immune features, we aimed to detect singular characteristics… read more here.
Keywords: characteristics immune; immune thrombocytopaenia; platelet immune; immune characteristics ... See more keywords
Antinuclear antibodies in childhood immune thrombocytopaenia: An increased risk for development of autoimmune disorders?
Sign Up to like & getrecommendations! Published in 2023 at "British journal of haematology"
DOI: 10.1111/bjh.18795
Abstract: Antinuclear antibodies (ANA) have been detected in children with primary immune thrombocytopaenia (ITP), but the effect of ANA titres on clinical outcomes is unclear. Liu et al. retrospectively analysed a cohort of 324 children with… read more here.
Keywords: thrombocytopaenia; increased risk; children primary; immune thrombocytopaenia ... See more keywords
Australian and New Zealand consensus guideline for paediatric newly diagnosed immune thrombocytopaenia endorsed by Australian New Zealand Children's Haematology and Oncology Group
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Paediatrics and Child Health"
DOI: 10.1111/jpc.16395
Abstract: In children, the majority of cases are self‐limiting and thus many paediatric patients can be managed conservatively with minimal complications. This varies considerably compared to adult newly diagnosed immune thrombocytopaenia (NDITP) where, in most cases,… read more here.
Keywords: australian new; oncology; new zealand; immune thrombocytopaenia ... See more keywords
Immunomodulatory cytokine interleukin-35 and immune thrombocytopaenia
Sign Up to like & getrecommendations! Published in 2020 at "Journal of International Medical Research"
DOI: 10.1177/0300060520976477
Abstract: Considerable attention has been paid to interleukin (IL)-35 because of its immunosuppressive effects in a variety of autoimmune diseases. IL-35, a recently identified cytokine of the IL-12 family, is a negative regulatory factor secreted by… read more here.
Keywords: immune thrombocytopaenia; cytokine interleukin; interleukin immune; thrombocytopaenia ... See more keywords