Vaccine‐induced immune thrombotic thrombocytopenia after vaccination against Covid‐19: A clinical dilemma for clinicians and patients
Sign Up to like & getrecommendations! Published in 2021 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2273
Abstract: Summary The coronavirus disease 2019 (Covid‐19) pandemic has had devastating effects on public health worldwide, but the deployment of vaccines for Covid‐19 protection has helped control the spread of SARS Coronavirus 2 (SARS‐CoV‐2) infection where… read more here.
Keywords: immune thrombotic; covid; induced immune; vaccine induced ... See more keywords
Pregnancy and non-pregnancy related immune thrombotic thrombocytopenic purpura in women of reproductive age
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-020-02133-4
Abstract: Pregnancy is a precipitating factor for immune thrombotic thrombocytopenic purpura (iTTP). We compared the clinical course and outcomes of iTTP in women of reproductive age, between those with pregnancy- and non-pregnancy-related iTTP. A review of… read more here.
Keywords: pregnancy; non pregnancy; pregnancy non; immune thrombotic ... See more keywords
Von Willebrand factor assays in patients with acquired immune thrombotic thrombocytopenia purpura treated with caplacizumab
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18080
Abstract: Acquired immune thrombotic thrombocytopenic purpura (iTTP) is a rare disease with a poor prognosis if undiagnosed. It is caused by autoantibody production to the von Willebrand factor (VWF) cleaving protease, A disintegrin and metalloproteinase with… read more here.
Keywords: immune thrombotic; vwf; factor; activity ... See more keywords
COVID‐19: Vaccine‐induced immune thrombotic thrombocytopenia
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Haematology"
DOI: 10.1111/ejh.13855
Abstract: In late February 2021, a prothrombotic syndrome was encountered for the first time in some of the recipients of ChAdOx1 CoV‐19 vaccine (AstraZeneca, University of Oxford, and Serum Institute of India). Since the hallmark of… read more here.
Keywords: immune thrombotic; thrombocytopenia; vaccine induced; covid vaccine ... See more keywords
Recommendations for the clinical and laboratory diagnosis of vaccine‐induced immune thrombotic thrombocytopenia (VITT) for SARS‐CoV‐2 infections: Communication from the ISTH SSC Subcommittee on Platelet Immunology.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.15341
Abstract: Vaccine campaigns are currently underway worldwide to combat the COVID-19 pandemic. The newly developed vaccines are highly effective with minimal adverse effects. Recently, the AstraZeneca vaccine has raised public alarm with concerns regarding the rare,… read more here.
Keywords: immune thrombotic; thrombocytopenia; vaccine; immunology ... See more keywords
Characterization of efficacy and safety of pathogen inactivated and quarantine plasma in routine use for treatment of acquired immune thrombotic thrombocytopenic purpura
Sign Up to like & getrecommendations! Published in 2018 at "Vox Sanguinis"
DOI: 10.1111/vox.12663
Abstract: Auto‐immune thrombotic thrombocytopenic purpura (TTP) is a morbid multi‐organ disorder. Cardiac involvement not recognized in initial disease descriptions is a major cause of morbidity. Therapeutic plasma exchange (TPE) requires exposure to multiple plasma donors with… read more here.
Keywords: thrombotic thrombocytopenic; thrombocytopenic purpura; plasma; immune thrombotic ... See more keywords
Thrombus Distribution in Vaccine-induced Immune Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Radiology"
DOI: 10.1148/radiol.220365
Abstract: Vaccination strategies have been at the forefront of controlling the COVID-19 pandemic. An association between vaccine-induced immune thrombotic thrombocytopenia (VITT) and one of these vaccines, the ChAdOx1 nCov-19 vaccine, is now recognized. The purpose of… read more here.
Keywords: radiology; immune thrombotic; vaccine; vaccine induced ... See more keywords
Vaccine-induced immune thrombotic thrombocytopenia with atypical vein thrombosis: Implications for clinical practice
Sign Up to like & getrecommendations! Published in 2022 at "Phlebology"
DOI: 10.1177/02683555211068948
Abstract: Objectives Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a new and rare syndrome resulting from the largest vaccination campaign against SARS-CoV-2 in the history of mankind. The aim of this review is to clarify underlying mechanisms,… read more here.
Keywords: immune thrombotic; vaccine induced; treatment; thrombotic thrombocytopenia ... See more keywords
ADAMTS13 Autoantibodies and Burden of Care in Immune Thrombotic Thrombocytopenic purpura: New Evidence and Future Implications
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Applied Thrombosis/Hemostasis"
DOI: 10.1177/10760296221125785
Abstract: The introduction Caplacizumab in the management of Immune thrombotic thrombocytopenic purpura (iTTP) has raised different questions, considering its cost-efficacy and the optimal immunosuppressive treatment (IST) to associate. A retrospective multicenter collection of 42 first iTTP… read more here.
Keywords: immune thrombotic; care; thrombotic thrombocytopenic; thrombocytopenic purpura ... See more keywords
Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know
Sign Up to like & getrecommendations! Published in 2021 at "Blood"
DOI: 10.1182/blood.2021012152
Abstract: In this timely Blood Spotlight, Arepally and Ortel discuss the latest information about VITT and highlight key “knowns” as well as pertinent “unknowns.” They also review appropriate treatments for this rare, but important complication of… read more here.
Keywords: immune thrombotic; induced immune; thrombocytopenia know; vaccine induced ... See more keywords
Mechanisms of Inhibition of Human Monoclonal Antibodies in Immune Thrombotic Thrombocytopenic Purpura.
Sign Up to like & getrecommendations! Published in 2023 at "Blood"
DOI: 10.1182/blood.2022019252
Abstract: Antibody binding to a plasma metalloprotease ADAMTS13 is necessary for the development of immune thrombotic thrombocytopenic purpura (iTTP). Inhibition of ADAMTS13-mediated VWF cleavage by such antibodies clearly plays a role in the pathophysiology of the… read more here.
Keywords: inhibition; immune thrombotic; human monoclonal; thrombotic thrombocytopenic ... See more keywords