Importance of antibody isotypes in antitumor immunity by monocytes and complement using human‐immune tumor models
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202048885
Abstract: Monoclonal antibodies (mAbs) have revolutionized clinical medicine, especially in the field of cancer immunotherapy. The challenge now is to improve the response rates, as immunotherapy still fails for many patients. Strategies to enhance tumor cell… read more here.
Keywords: immune tumor; human immune; importance antibody; immunology ... See more keywords
Dysfunctions of innate and adaptive immune tumor microenvironment in Waldenström macroglobulinemia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34405
Abstract: Waldenström macroglobulinemia (WM) is a rare subtype of non‐Hodgkin lymphoma characterized by malignant lymphoplasmacytic cells in the bone marrow (BM). To dissect the pathophysiology of WM, we evaluated clonal cells by mapping of B cell… read more here.
Keywords: waldenstr macroglobulinemia; tumor microenvironment; innate adaptive; adaptive immune ... See more keywords
Characterization of the immune tumor microenvironment of HER2-positive breast cancer following treatment with entinostat and immune checkpoint inhibition.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e15061
Abstract: e15061Background: HER2+ breast cancers are known to be less-immunogenic and associated with low response rates to immune checkpoint inhibitors (ICIs). A combination of immunosuppressive signals tha... read more here.
Keywords: immune checkpoint; breast; immune tumor; characterization immune ... See more keywords
Ultrasound and laser-promoted dual-gas nano-generator for combined photothermal and immune tumor therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1005520
Abstract: The combination of photothermal therapy (PTT) and immune tumor therapy has emerged as a promising avenue for cancer treatment. However, the insufficient immune response caused by inefficient immunogenic cell death (ICD) inducers and thermal resistance,… read more here.
Keywords: tumor therapy; therapy; laser promoted; ultrasound laser ... See more keywords
Extracellular Vesicles Orchestrate Immune and Tumor Interaction Networks
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DOI: 10.3390/cancers12123696
Abstract: Simple Summary Significant strides have been made to describe the pervasive role of extracellular vesicles (EVs) in health and disease. This work provides an insightful and unifying mechanistic understanding of EVs in immunity and tumorigenesis.… read more here.
Keywords: extracellular vesicles; interaction networks; tumor interaction; immune tumor ... See more keywords