Association Between Risk of COVID-19 Infection in Nonimmune Individuals and COVID-19 Immunity in Their Family Members.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2021.5814
Abstract: Importance The association between COVID-19 immunity within families and the risk of infection in nonimmune family members is unknown. Objective To investigate the association between risk of COVID-19 in nonimmune individuals and the number of… read more here.
Keywords: covid infection; family members; immunity; family ... See more keywords
SARS-CoV-2 Attack Rate and Population Immunity in Southern New England, March 2020 to May 2021
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.14171
Abstract: Key Points Question What proportion of individuals living in southern New England had immunity to SARS-CoV-2, either through past infection or vaccination, by May 31, 2021? Findings This case series analysis for Rhode Island, Massachusetts,… read more here.
Keywords: may 2021; new england; southern new; immunity ... See more keywords
Self-immunity to antibacterial peptides by ABC transporters.
Sign Up to like & getrecommendations! Published in 2020 at "FEBS letters"
DOI: 10.1002/1873-3468.13953
Abstract: Bacteria produce under certain stress conditions bacteriocins and microcins that display antibacterial activity against closely related species for survival. Bacteriocins and microcins exert their antibacterial activity by either disrupting the membrane or inhibiting essential intracellular… read more here.
Keywords: abc transporters; bacteriocins microcins; immunity; antibacterial peptides ... See more keywords
The immunity-related GTPase IRGC mediates interaction between lipid droplets and mitochondria to facilitate sperm motility.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14640
Abstract: The immunity-related GTPases (IRGs) belong to the interferon-inducible GTPase protein family, which mediates cell-autonomous and innate immunity response to intracellular pathogens. Yet, the cellular and physiological function of IRGC, a member of the IRG subfamily,… read more here.
Keywords: immunity related; lipid droplets; immunity; sperm motility ... See more keywords
Rapid Screen for Antiviral T‐Cell Immunity with Nanowire Electrochemical Biosensors
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202109661
Abstract: The ability to rapidly assess and monitor patient immune responses is critical for clinical diagnostics, vaccine design, and fundamental investigations into the presence or generation of protective immunity against infectious diseases. Recently, findings on the… read more here.
Keywords: cell; screen antiviral; immunity; rapid screen ... See more keywords
Extracellular‐Vesicle‐Based Drug Delivery Systems for Enhanced Antitumor Therapies through Modulating the Cancer‐Immunity Cycle
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202201054
Abstract: Although immunotherapy harnessing activity of the immune system against tumors has made great progress, the treatment efficacy remains limited in most cancers. Current anticancer immunotherapy is primarily based on T‐cell‐mediated cellular immunity, which highly relies… read more here.
Keywords: cancer immunity; immunity; immunity cycle; drug delivery ... See more keywords
Nanomaterials‐Mediated Co‐Stimulation of Toll‐Like Receptors and CD40 for Antitumor Immunity
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202207486
Abstract: Toll‐like receptors (TLRs) and CD40‐related signaling pathways represent critical bridges between innate and adaptive immune responses. Here, an immunotherapy regimen that enables co‐stimulation of TLR7/8‐ and CD40‐mediated pathways is developed. TLR7/8 agonist resiquimod (R848) derived… read more here.
Keywords: toll like; immunity; stimulation; nanomaterials mediated ... See more keywords
A DNA/DMXAA/Metal–Organic Framework Activator of Innate Immunity for Boosting Anticancer Immunity
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210440
Abstract: Immunotherapy has achieved revolutionary success in clinics, but it remains challenging for treating hepatocellular carcinoma (HCC) characterized by high vascularization. Here, it is reported that metal–organic framework‐801 (MOF‐801) can be employed as a stimulator of… read more here.
Keywords: dna dmxaa; organic framework; immunity; metal organic ... See more keywords
Albumin-Hitchhiking Drug Delivery to Tumor-draining Lymph Nodes Precisely Boosts Tumor-Specific Immunity through Autophagy Modulation of Immune Cells.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202211055
Abstract: Tumor-draining lymph nodes (TDLNs) are the first sites where tumor components reach and dendritic cells (DCs) present tumor-associated antigens to T cells. DCs rely on autophagy to process tumor antigens into epitope peptides to form… read more here.
Keywords: draining lymph; immunity; tumor draining; lymph nodes ... See more keywords
Biomimetic Nanocarriers Guide Extracellular ATP Homeostasis to Remodel Energy Metabolism for Activating Innate and Adaptive Immunity System
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105376
Abstract: Metabolic interventions via targeting intratumoral dysregulated metabolism pathways have shown promise in reinvigorating antitumor immunity. However, approved small molecule immunomodulators often suffer from ineffective response rates and severe off‐target toxicity. ATP occupies a crucial role… read more here.
Keywords: metabolism; energy metabolism; immunity; tumor ... See more keywords
Cancer Nanobombs Delivering Artoxplatin with a Polyigniter Bearing Hydrophobic Ferrocene Units Upregulate PD-L1 Expression and Stimulate Stronger Anticancer Immunity.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300806
Abstract: Poor immunogenicity seriously hampers the broader implementation of antitumor immunotherapy. Enhanced immunogenicity capable of achieving greater antitumor immunity is urgently required. Here, a novel polymer that contains hydrophobic ferrocene (Fc) units and thioketal bonds in… read more here.
Keywords: cancer; ferrocene units; immunity; antitumor immunity ... See more keywords